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Advances in structure of membrane proteins /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Stepanenko, Aleksei Anatoliyovych
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Oakville, ON : Delve Publishing, 2019.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Cover; Half Title Page; Title Page; Copyright Page; Declaration; About the Editor; Table of Contents; List of Contributors; List of Abbreviations; Preface; Chapter 1 Retinal Cyclic Nucleotide-Gated Channels: From Pathophysiology to Therapy; Abstract; Introduction; Structure, Basic Properties and Activation of CNG Channels; Signal Transduction in Photoreceptors; In Vivo Analysis of CNG Channel Function: Analysis of Genetic Mouse Models and Human Channelopathies; Gene Therapy for the Treatment of CNG Channelopathies; Gene Therapy for CNG Channel-Linked RP
  • Gene Therapy for CNG Channel-Linked ACHMReferences; Chapter 2 Gonadotropin-Releasing Hormone (GnRH) Receptor Structure and GnRH Binding; Abstract; Introduction; Primary Structures of GnRH Receptors; The Three-Dimensional Structure of the GnRH Receptor; Ligand-Binding Interactions; Concluding Remarks; Author Contributions; Footnotes; References; Chapter 3 Exploring G Protein-Coupled Receptors (GPCRs) Ligand Space via Cheminformatics Approaches: Impact on Rational Drug Design; Abstract; Introduction; Booming Age of GPCR Structural Biology; Insights Into GPCR Ligand Space
  • Chapter 5 Structural Probing and Molecular Modeling of the A3 Adenosine Receptor: A Focus on Agonist BindingAbstract; Introduction; Structural Probing of the A3 Adenosine Receptor; Molecular Modeling of the A3 Adenosine Receptor; Library Screening to Discover Novel Ligands of the A3 Adenosine Receptor; Receptor Dimerization; Conclusions; Acknowledgments; References; Chapter 6 Methods used to Study the Oligomeric Structure of G-protein-coupled Receptors; Abstract; Introduction; Methods to Study Oligomers of GPCRs; BN-PAGE; Concluding remarks; Abbreviations; Funding; References; Abstract.