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Advances in structure of membrane proteins /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Stepanenko, Aleksei Anatoliyovych
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Oakville, ON : Delve Publishing, 2019.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Advances in structure of membrane proteins /  |c edited by: Aleksei Anatoliyovych Stepanenko. 
260 |a Oakville, ON :  |b Delve Publishing,  |c 2019. 
300 |a 1 online resource (450 pages) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
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505 0 |a Cover; Half Title Page; Title Page; Copyright Page; Declaration; About the Editor; Table of Contents; List of Contributors; List of Abbreviations; Preface; Chapter 1 Retinal Cyclic Nucleotide-Gated Channels: From Pathophysiology to Therapy; Abstract; Introduction; Structure, Basic Properties and Activation of CNG Channels; Signal Transduction in Photoreceptors; In Vivo Analysis of CNG Channel Function: Analysis of Genetic Mouse Models and Human Channelopathies; Gene Therapy for the Treatment of CNG Channelopathies; Gene Therapy for CNG Channel-Linked RP 
505 8 |a Gene Therapy for CNG Channel-Linked ACHMReferences; Chapter 2 Gonadotropin-Releasing Hormone (GnRH) Receptor Structure and GnRH Binding; Abstract; Introduction; Primary Structures of GnRH Receptors; The Three-Dimensional Structure of the GnRH Receptor; Ligand-Binding Interactions; Concluding Remarks; Author Contributions; Footnotes; References; Chapter 3 Exploring G Protein-Coupled Receptors (GPCRs) Ligand Space via Cheminformatics Approaches: Impact on Rational Drug Design; Abstract; Introduction; Booming Age of GPCR Structural Biology; Insights Into GPCR Ligand Space 
505 8 |a Chapter 5 Structural Probing and Molecular Modeling of the A3 Adenosine Receptor: A Focus on Agonist BindingAbstract; Introduction; Structural Probing of the A3 Adenosine Receptor; Molecular Modeling of the A3 Adenosine Receptor; Library Screening to Discover Novel Ligands of the A3 Adenosine Receptor; Receptor Dimerization; Conclusions; Acknowledgments; References; Chapter 6 Methods used to Study the Oligomeric Structure of G-protein-coupled Receptors; Abstract; Introduction; Methods to Study Oligomers of GPCRs; BN-PAGE; Concluding remarks; Abbreviations; Funding; References; Abstract. 
504 |a Includes bibliographical references and index. 
588 0 |a Print version record. 
590 |a eBooks on EBSCOhost  |b EBSCO eBook Subscription Academic Collection - Worldwide 
650 0 |a Membrane proteins  |x Structure. 
650 6 |a Protéines membranaires  |x Structure. 
700 1 |a Stepanenko, Aleksei Anatoliyovych. 
776 0 8 |i Print version:  |a Stepanenko, Aleksei Anatoliyovych.  |t Advances in structure of membrane proteins.  |d Ashland : Delve Publishing, ©2019 
856 4 0 |u https://ebsco.uam.elogim.com/login.aspx?direct=true&scope=site&db=nlebk&AN=2013988  |z Texto completo 
880 8 |6 505-00/(S  |a Cheminformatics-Based Paradigms In GPCR Drug DiscoverySummary of Cheminformatics Softwares/Tools Utilized In GPCR Drug Discovery; Conclusions; Author Contributions; Conflict of Interest Statement; Acknowledgments; References; Chapter 4 Application of Solution NMR to Structural Studies on α-Helical Integral Membrane Proteins; Abstract; Introduction; General Approaches to Structural Studies on Integral MPs; Illustration of Successful Structure Determination of Integral MPs; Conclusions; Acknowledgments; References 
880 8 |6 505-00/(S  |a Chapter 7 Spatial Intensity Distribution Analysis: Studies of G Protein-Coupled Receptor OligomerisationAbstract; Trends; SpIDA: An Approach to Detect Protein Oligomerisation State; Advantages and Limitations of SpIDA for Quantification of Protein Oligomeric State; Use of SpIDA to Define the Quaternary Structure of GPCRs; Using SpIDA to Examine Potential Ligand-Induced Alterations of GPCR Quaternary Structure; Concluding Remarks; Disclaimer Statement; Acknowledgments; Glossary; References; Chapter 8 Structure, Function, Pharmacology, and Therapeutic Potential of the G Protein, Gα/q,11 
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