Proteomics in Biomarker Identification /
Clasificación: | Libro Electrónico |
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Autor principal: | |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
Oakville, ON, Canada :
Society Publishing,
2019.
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Edición: | E-book edition. |
Temas: | |
Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Cover; Half Title Page; Title Page; Copyright Page; About The Author; Table of Contents; List of Figures; List of Tables; List of Abbreviations; Preface; Chapter 1 Biomarkers: An Overview; 1.1. Introduction; 1.2. Classification of Biomarkers; 1.3. Types of Biomarkers Based on Different "Omics; 1.4. Biomarker Specifications; 1.5. An Overview of Biomarkers In A Clinical Scenario; 1.6. Characters of Ideal Biomarkers; 1.7. Biomarkers or Clinical Endpoints; 1.8. Merits And Demerits of Biomarkers As Surrogate Endpoints; 1.9. Which Are The Biomarkers Used?; 1.10. Gist of Significance of Biomarkers
- 1.11. Case Studies of Analysis of Biomarkers In A Clinical Context1.12. Discovery and Validation of Biomarkers; 1.13. Biomarkers In A Clinical Scenario: Approach; 1.14. Valid Biomarkers and Clinical Research; 1.15. Case Study of Biomarkers Detected By Metabolomics; 1.16. Summary; References; Chapter 2 Proteomics: An Overview of Techniques Involved; 2.1. Design of Biomarkers; 2.2. Biobanking of Samples; 2.3. Proteomics And Discovery of Biomarkers; 2.4. A Quick Snapshot; 2.5. Techniques For Biomarker Discovery Using Proteomics; 2.6. The Mass Analyzers; 2.7. Variations of Ms
- 2.8. Variations In Ms Technologies In Proteomics2.9. Ief Fractionation Methods; 2.10. 2D Gel Electrophoresis (2-De); 2.11. 2D Difference Gel Electrophoresis (2D-Dige); 2.12. Stable Isotope Labeling by Amino Acids In Cell Culture (SILAC); 2.13. Isotope-Coded Affinity Tag (ICAT); 2.14. Western Blotting; 2.15. 18O Stable Isotope Labeling; 2.16. Isobaric Tagging Reagent For Absolute Quantitation (ITRAQ); 2.17. Ce-Ms; 2.18. Stable Isotope Dilution Mass Spectrometry (SID-MS); 2.19. Microarrays; 2.20. Multidimensional Protein Identification Technology (MUDPIT); 2.21. Label-Free Techniques
- 2.22. Another Proteomics For Biomarker Discovery2.23. Bioinformatics and Proteomics And Biomarkers; 2.24. Glimpses of Discovery of Biomarkers Using Proteomics; 2.25. Case Studies: Biomarkers of Bladder Cancer Using Proteomics; 2.26. Final Note; References; Chapter 3 Microbial Biomarkers Proteomics; 3.1. Typing Of Microbes; 3.2. Typing Methods; 3.3. Phenotypic Methods; 3.4. Genotypic Methods; 3.5. Diagnosis Of Microbial Infections Using Biomarkers; 3.6. What Is The Role Of A Biomarker From The Host?; 3.7. Biomarkers And Antibiotics: A Scenario; 3.8. Biomarkers That Are Routinely Analyzed
- 3.9. Biomarkers For The Future3.10. What's New?; 3.11. Proteome For Biomarkers Of Bacteria And Virus; 3.12. Host-Pathogen Protein-Protein Interactions; 3.13. Intact Proteins; 3.14. Direct Interactions And Their Detections; 3.15. Posttranslational Modifications That Are Regulated By Pathogen; 3.16. Summary; References; Chapter 4 Plant Biomarkers Discovery by Proteomics; 4.1. Introduction; 4.2. Why Proteomics For Plant Biomarkers?; 4.3. Approaches For Plant Biomarkers; 4.4. Proteomics For Reactive Oxygen Species Research; 4.5. Stress Responses In Two Plants: Proteomics For Biomarkers