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Systems thinking in medicine and new drug discovery. Volume two /
This second book in a two-volume set tells how the healthcare community is working with patients and their caregivers to help improve health using P4 medicine, proper nutrition and a healthy lifestyle. The healthcare community is finding ways to predict one's susceptibility to diseases, so they...
| Clasificación: | Libro Electrónico |
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| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Newcastle upon Tyne :
Cambridge Scholars Publishing,
2018.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Intro; Contents; Preface; Chapter One; 1.1 P4 medicine: predictive, preventive, personalized and participatory; 1.2 Systems primary care medicine; 1.3 Causality in P4SM; 1.4 Explanation, prediction and control in P4 me; 1.5 What P4 medicine does; 1.6 Examples of P4 medicine; 1.7 Important collaborations in P4 medicine; 1.8 P4 and evidence based medicine; 1.9 The Advancing Regulatory Science Initiative; 1.10 The voices of the people; 1.11 Limitations of P4 medicine; 1.12 Metabolomics; 1.12.1 Introduction; 1.12.2 Comparison of LC-MS and GC-MS; 1.12.3 NMR in metabolomics
- 1.12.4 Receiver operator characteristic (ROC) curves1.12.5 Acute kidney injury (AKI) metabolomics; 1.12.6 Chronic kidney disease (CKD) me; 1.12.7 Metabolomics of acute kidney injury; 1.12.8 Metabolomics of neonatal, pediatric and childhood kidney diseases; 1.12.9 Metabolomics of kidney cancer; 1.12.10 Proteomics; 1.13 Targeted radiation therapy; 1.14 Precision systems medicine that targets cancer stem cel; 1.15 Cancer prevention; 1.16 Systems medicine; References; Chapter Two; 2.1 Previous misconceptions caused by reductionist thinking; 2.2 Chemistry of free radicals and RONS
- 2.3 How antioxidants really work2.3.1 Poorly liganded iron and the Fenton reaction; 2.3.2 The Nrf2/ARE system; 2.4 The role of the Keap1-Nrf2-ARE signaling system in preventing cardiovascular diseases; 2.5 Role of the Nrf2/ARE antioxidant system in cancer and neurodegenerative diseases; 2.6 Smoldering inflammation; 2.7 The complement system and toll-like receptors in health and disease; References; Chapter Three; 3.1 Nutrition; 3.1.1 Fats; 3.1.2 Protein; 3.1.3 Carbohydrates; 3.1.4 Vitamins and; 3.1.5 Mother's milk
- the only true superfood; 3.2 Role of Lifestyle; References; Chapter Four
- 4.1 Introduction4.2 Epigenetic gene regulation; 4.3 Global climate change; References; Appendix; A1 Introduction; A2 The Nervous System; A2.1 Introduction; A2.2 Cells in the nervous system; A2.3 Regions of the brain; A2.4 Neurotransmitters, neurohormones and neuromodulators; A2.5 Small molecule neuroactive NO and CO; A3 The Endocrine System; A4 The Immune System; References; Abbreviations and Acronyms Used; Index