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Systems thinking in medicine and new drug discovery. Volume two /

This second book in a two-volume set tells how the healthcare community is working with patients and their caregivers to help improve health using P4 medicine, proper nutrition and a healthy lifestyle. The healthcare community is finding ways to predict one's susceptibility to diseases, so they...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Smith, Robert E., 1951- (Autor)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Newcastle upon Tyne : Cambridge Scholars Publishing, 2018.
Temas:
Acceso en línea:Texto completo

MARC

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245 1 0 |a Systems thinking in medicine and new drug discovery.  |n Volume two /  |c by Robert E. Smith. 
264 1 |a Newcastle upon Tyne :  |b Cambridge Scholars Publishing,  |c 2018. 
300 |a 1 online resource (xiv, 333 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references and index. 
588 0 |a Online resource; title from PDF title page (EBSCO, viewed January 8, 2019). 
505 0 |a Intro; Contents; Preface; Chapter One; 1.1 P4 medicine: predictive, preventive, personalized and participatory; 1.2 Systems primary care medicine; 1.3 Causality in P4SM; 1.4 Explanation, prediction and control in P4 me; 1.5 What P4 medicine does; 1.6 Examples of P4 medicine; 1.7 Important collaborations in P4 medicine; 1.8 P4 and evidence based medicine; 1.9 The Advancing Regulatory Science Initiative; 1.10 The voices of the people; 1.11 Limitations of P4 medicine; 1.12 Metabolomics; 1.12.1 Introduction; 1.12.2 Comparison of LC-MS and GC-MS; 1.12.3 NMR in metabolomics 
505 8 |a 1.12.4 Receiver operator characteristic (ROC) curves1.12.5 Acute kidney injury (AKI) metabolomics; 1.12.6 Chronic kidney disease (CKD) me; 1.12.7 Metabolomics of acute kidney injury; 1.12.8 Metabolomics of neonatal, pediatric and childhood kidney diseases; 1.12.9 Metabolomics of kidney cancer; 1.12.10 Proteomics; 1.13 Targeted radiation therapy; 1.14 Precision systems medicine that targets cancer stem cel; 1.15 Cancer prevention; 1.16 Systems medicine; References; Chapter Two; 2.1 Previous misconceptions caused by reductionist thinking; 2.2 Chemistry of free radicals and RONS 
505 8 |a 2.3 How antioxidants really work2.3.1 Poorly liganded iron and the Fenton reaction; 2.3.2 The Nrf2/ARE system; 2.4 The role of the Keap1-Nrf2-ARE signaling system in preventing cardiovascular diseases; 2.5 Role of the Nrf2/ARE antioxidant system in cancer and neurodegenerative diseases; 2.6 Smoldering inflammation; 2.7 The complement system and toll-like receptors in health and disease; References; Chapter Three; 3.1 Nutrition; 3.1.1 Fats; 3.1.2 Protein; 3.1.3 Carbohydrates; 3.1.4 Vitamins and; 3.1.5 Mother's milk -- the only true superfood; 3.2 Role of Lifestyle; References; Chapter Four 
505 8 |a 4.1 Introduction4.2 Epigenetic gene regulation; 4.3 Global climate change; References; Appendix; A1 Introduction; A2 The Nervous System; A2.1 Introduction; A2.2 Cells in the nervous system; A2.3 Regions of the brain; A2.4 Neurotransmitters, neurohormones and neuromodulators; A2.5 Small molecule neuroactive NO and CO; A3 The Endocrine System; A4 The Immune System; References; Abbreviations and Acronyms Used; Index 
520 |a This second book in a two-volume set tells how the healthcare community is working with patients and their caregivers to help improve health using P4 medicine, proper nutrition and a healthy lifestyle. The healthcare community is finding ways to predict one's susceptibility to diseases, so they can be prevented from occurring, when possible. When diseases do emerge, it is developing personalized therapies and ways for patients to participate in their own healthcare. At the same time, systems thinking dispels many misconceptions, such as 'natural' foods and 'superfoods'. In fact, the only true. 
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650 0 |a Human biology. 
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650 6 |a Médecine intégrative. 
650 6 |a Biologie humaine. 
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650 7 |a Drug development  |2 fast 
650 7 |a Human biology  |2 fast 
650 7 |a Integrative medicine  |2 fast 
650 7 |a Pharmaceutical chemistry  |2 fast 
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