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Atlas of cilia bioengineering and biocomputing /

Cilia are microscopic finger-like cell-surface organelles possessed by a great many eukaryotic organisms, including humans, whose purposes include generating local fluid movements via rhythmic whip-like beating and environmental sensing. Despite intense research efforts since their discovery by van...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Mayne, Richard (Editor ), Toonder, Jaap M. J. den (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Gistrup, Denmark : River Publishers, [2018]
Colección:River Publishers series in biomedical engineering.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; Half Title Page; RIVER PUBLISHERS SERIES IN BIOMEDICALENGINEERING; Title Page; Copyright Page; Contents; Editor Foreword; List of Contributors; List of Figures; List of Tables; List of Abbreviations; PART I : Biology; Chapter 1
  • Biological Preliminaries for Cilia Study; 1.1 Introduction; 1.2 Primary Cilia; 1.3 Motile Cilia; 1.3.1 Structure; 1.3.2 The Ciliary Beat; References; Chapter 2
  • Genetic Engineering of Ciliated Cells; 2.1 Introduction; 2.2 Cell Selection and Growth; 2.2.1 Cells with Primary Cilia; 2.2.2 Cells with Motile Cilia; 2.3 Transfection of Cells.
  • 2.4 RNA Interference2.5 Fluorescent Protein Labeling; 2.6 Optogenetics; 2.7 Proximity-Dependent Biotinylation (BioID); 2.8 Tandem Affinity Purification (TAP); 2.9 Genome Editing Using TALENs, Zn Finger Nucleases, CRISPR/Cas9, and Base Editing; Acknowledgments; References; Chapter 3
  • Programming Ciliary Object Manipulation; 3.1 Introduction; 3.2 Sorting by Paramecium Cilia; 3.3 Reprogramming Paramecium Cilia; Reference; PART II : Engineering; Chapter 4
  • Robotic Cilia for Autonomous Parallel Distributed Sorting Platforms; 4.1 Introduction; 4.2 Engineering Sorting Ciliary Platforms; References.
  • Chapter 5
  • Artificial Pneumatic Cilia5.1 Introduction; 5.2 Base Actuated Pneumatic Cilia; 5.3 Body Actuated Pneumatic Cilia; 5.4 Conclusion; Acknowledgments; References; Chapter 6
  • Blinking-Vortex Inspired Mixing with Cilia; 6.1 Cilia Actuation Scheme; 6.2 Experiments and Simulations; 6.3 Results; References; Chapter 7
  • Magnetic Thin-film Cilia for Microfluidic Applications; 7.1 Introduction; 7.2 Fabrication of Magnetic Cilia; 7.3 Fluid Transport by An Array of Beating Magnetic Cilia; 7.4 Kinematics of Magnetic Cilia; 7.4.1 Counter-Clockwise Rotation of Magnetic Field.
  • 7.4.2 Clockwise Rotation of Magnetic Field7.5 Metachronal Motion; 7.6 Microfluidic Applications of Artificial Cilia; 7.6.1 Microfluidic Mixing; 7.6.2 Bacteria Capture; 7.7 Summary; Acknowledgments; References; Chapter 8
  • Artificial Cilia: Fabrication, Actuation, and Flow Generation; 8.1 Introduction; References; PART III : Theoretical and Computer Modelling; Chapter 9
  • Numerical Simulations of Fluid Transport by Magnetically Actuated Artificial Cilia; 9.1 Introduction; References; Chapter 10
  • Modeling Gel-based Artificial Cilia; 10.1 Introduction.
  • 10.2 Designing Chemo-responsive Cilial Systems10.2.1 Methodology: Gel Lattice Spring Model; 10.2.2 Self-oscillating Cilia; 10.3 Photo-responsive Gel-Fiber Systems; 10.4 Capturing Hydrodynamic Interactions in Complex Fluids; 10.4.1 Methodology; 10.4.2 Utilizing Oscillating Rods to "Catch and Release" Targeted Nanoparticles; 10.5 Artificial Cilia Based on Biological Aptamers; 10.5.1 Methodology; 10.5.2 Catch and Release with Aptamer-mimicking Cilia; 10.6 Conclusions; References; Index; About the Editors; Back Cover.