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Frontiers in Stem Cell and Regenerative Medicine Research.
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| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Sharjah :
Bentham Science Publishers,
2018.
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| Colección: | Frontiers in Stem Cell and Regenerative Medicine Research Ser.
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| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Intro; CONTENTS; PREFACE; List of Contributors; Alternative Models of Cancer Stem Cells: Implications for Translational Oncology; Vivek Kaushik, Juan Sebastian Yakisich, Neelam Azad and Anand Krishnan V. Iyer*; INTRODUCTION; Normal Stem cells, Cancer Stem Cells and Stemness; Tumor Heterogeneity; Cancer Biology Models: Historical Overview; Clonal Evolution Model (CEM); Classical Cancer Stem Cell Model (CCSCM); Stemness Phenotype Model (SPM); Complex System Model (CSM); Reprogramming Model (RM); Dynamic Cancer Stem Cell Model (DCSCM); Plasticity Model (PM).
- The Epithelial-Mesenchymal Transition (EMT) in Cancer PlasticityBiological Implications: Plasticity, Origin of Intratumoral Heterogeneity and Chemoresistance; Clinical Implications for Targeted Therapy; Implications for Therapeutic Development; Future Directions in Preclinical & Clinical Research; CONCLUSIONS; CONSENT FOR PUBLICATION; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Unravelling Mesenchymal Stem Cell Signature in Regenerative Medicine; Genni Desiato1,2,3, Morris Losurdo1,2, Chiara A. Elia3, Anna Saccomano1 and Silvia Coco1,2,*
- A BIT OF HISTORY TO INTRODUCE REGENERATIVE MEDICINEMULTIPOTENT MESENCHYMAL STROMAL CELL POPULATIONS: ISOLATION, PHENOTYPE AND PROPERTIES; Stemness in Adult Tissues; The Discovery of Bone Marrow Source of Mesenchymal Stem Cells; Clarifying Mesenchymal Stem Cells Nomenclature; Hallmarks For Defining Human Mesenchymal Stem Cells; Drawing A Map Of Mesenchymal Stem Cells Tissues And Sources; Are All Mesenchymal Stem Cells Equivalent?; PARACRINE MODULATION VERSUS TRANSDIFFERENTIATION: REPARATIVE AND IMMUNOMODULATORY FEATURES.
- Exploiting Mesenchymal Stem Cell Paracrine Abilities for Tissue Regeneration and RepairThe Specific Interaction with Cells of the Immune System; The Specific Interaction of Mesenchymal Stem Cells with Tumorigenic Cells; EXTRACELLULAR VESICLES AS A TOOL FOR CLINICAL APPLICATIONS; MSC REGENERATIVE POTENTIAL; Why Mesenchymal Stem Cells?; Mesenchymal Stem Cells In Osteogenesis Imperfecta; Mesenchymal Stem Cells in Osteoarthritis; Mesenchymal Stem Cells in Acute Kidney Injury; Mesenchymal Stem Cells in Myocardial Infarction; Mesenchymal Stem Cells in Wound Healing.
- Mesenchymal Stem Cell In Neurodegenerative DiseasesMesenchymal Stem Cells in Clinical Trials at a Glance; GENETICALLY MODIFIED MSCS: TOWARDS INCREASING THEIR THERAPEUTIC POTENTIAL; Mesenchymal Stem Cell Migration and Homing; Mesenchymal Stem Cell Engineering to Improve their Abilities; Improvement of Mesenchymal Stem Cell Functionality; Overexpression of Regulatory Molecules; CONCLUSION; CONSENT FOR PUBLICATION; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Stem Cells in Orthopaedic Injuries; Bogdan A. Matache1,2, Stephanie C. Petterson1,* and Kevin D. Plancher1,3,4; INTRODUCTION.