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Frontiers in Stem Cell and Regenerative Medicine Research.

Detalles Bibliográficos
Autor principal: Atta-ur-Rahman
Otros Autores: Anjum, Shazia
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Sharjah : Bentham Science Publishers, 2018.
Colección:Frontiers in Stem Cell and Regenerative Medicine Research Ser.
Acceso en línea:Texto completo

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245 1 0 |a Frontiers in Stem Cell and Regenerative Medicine Research. 
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490 1 |a Frontiers in Stem Cell and Regenerative Medicine Research Ser. ;  |v v. 8 
588 0 |a Print version record. 
505 0 |a Intro; CONTENTS; PREFACE; List of Contributors; Alternative Models of Cancer Stem Cells: Implications for Translational Oncology; Vivek Kaushik, Juan Sebastian Yakisich, Neelam Azad and Anand Krishnan V. Iyer*; INTRODUCTION; Normal Stem cells, Cancer Stem Cells and Stemness; Tumor Heterogeneity; Cancer Biology Models: Historical Overview; Clonal Evolution Model (CEM); Classical Cancer Stem Cell Model (CCSCM); Stemness Phenotype Model (SPM); Complex System Model (CSM); Reprogramming Model (RM); Dynamic Cancer Stem Cell Model (DCSCM); Plasticity Model (PM). 
505 8 |a The Epithelial-Mesenchymal Transition (EMT) in Cancer PlasticityBiological Implications: Plasticity, Origin of Intratumoral Heterogeneity and Chemoresistance; Clinical Implications for Targeted Therapy; Implications for Therapeutic Development; Future Directions in Preclinical & Clinical Research; CONCLUSIONS; CONSENT FOR PUBLICATION; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Unravelling Mesenchymal Stem Cell Signature in Regenerative Medicine; Genni Desiato1,2,3, Morris Losurdo1,2, Chiara A. Elia3, Anna Saccomano1 and Silvia Coco1,2,* 
505 8 |a A BIT OF HISTORY TO INTRODUCE REGENERATIVE MEDICINEMULTIPOTENT MESENCHYMAL STROMAL CELL POPULATIONS: ISOLATION, PHENOTYPE AND PROPERTIES; Stemness in Adult Tissues; The Discovery of Bone Marrow Source of Mesenchymal Stem Cells; Clarifying Mesenchymal Stem Cells Nomenclature; Hallmarks For Defining Human Mesenchymal Stem Cells; Drawing A Map Of Mesenchymal Stem Cells Tissues And Sources; Are All Mesenchymal Stem Cells Equivalent?; PARACRINE MODULATION VERSUS TRANSDIFFERENTIATION: REPARATIVE AND IMMUNOMODULATORY FEATURES. 
505 8 |a Exploiting Mesenchymal Stem Cell Paracrine Abilities for Tissue Regeneration and RepairThe Specific Interaction with Cells of the Immune System; The Specific Interaction of Mesenchymal Stem Cells with Tumorigenic Cells; EXTRACELLULAR VESICLES AS A TOOL FOR CLINICAL APPLICATIONS; MSC REGENERATIVE POTENTIAL; Why Mesenchymal Stem Cells?; Mesenchymal Stem Cells In Osteogenesis Imperfecta; Mesenchymal Stem Cells in Osteoarthritis; Mesenchymal Stem Cells in Acute Kidney Injury; Mesenchymal Stem Cells in Myocardial Infarction; Mesenchymal Stem Cells in Wound Healing. 
505 8 |a Mesenchymal Stem Cell In Neurodegenerative DiseasesMesenchymal Stem Cells in Clinical Trials at a Glance; GENETICALLY MODIFIED MSCS: TOWARDS INCREASING THEIR THERAPEUTIC POTENTIAL; Mesenchymal Stem Cell Migration and Homing; Mesenchymal Stem Cell Engineering to Improve their Abilities; Improvement of Mesenchymal Stem Cell Functionality; Overexpression of Regulatory Molecules; CONCLUSION; CONSENT FOR PUBLICATION; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Stem Cells in Orthopaedic Injuries; Bogdan A. Matache1,2, Stephanie C. Petterson1,* and Kevin D. Plancher1,3,4; INTRODUCTION. 
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