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Tabla de Contenidos:
  • Intro; CONTENTS; PREFACE; List of Contributors; General Description of HPVs; Kimia Kardani and Azam Bolhassani*; INTRODUCTION; HPV and Cancer; HPV Classification; HPV Genome; CONCLUDING REMARKS; CONFLICT OF INTEREST; ACKNOWLEDGEMENT; REFERENCES; HPV Proteins and Their Functions; Kimia Kardani and Azam Bolhassani*; INTRODUCTION; Late Proteins; Major Capsid Protein (L1); Conserved Motifs of L1 Protein; Minor Capsid Protein (L2); The Role of L1 in Virus Entry; L2 Improves the Encapsidation of HPV Genome; L2 and Cell Host Entry; L2 and Vesicular Trafficking of Papillomavirus.
  • L2 and Endosomal EscapeNuclear Entry of HPV Genome by L2; Nuclear Activities of L2; Early or Regulatory Proteins; E1 Protein; E2 Protein; E4 Protein; E5 Protein; E6 Protein; E7 Protein; Regulation of Cellular miRNA Expression by Human Papillomaviruses; CONCLUDING REMARKS; CONFLICT OF INTEREST; ACKNOWLEDGEMENT; REFERENCES; Types of Benign or Malignant Diseases Associated with HPV Infections; Kimia Kardani and Azam Bolhassani*; INTRODUCTION; Five Genera of HPVs; Low-Risk HPV Types; High-Risk HPV Types; Novel Papillomaviruses; HPV125; HPV150 and HPV151; HPV120; HPV159; HPV174; HPV179 and HPV184.
  • HPV199HPV204; PsuPV1; HPV153; HPV154; HPV180; HPV155; HPV175; HPV178; HPV197; HPV198 and HPV203; HPV200, HPV201 and HPV202; Diseases Associated with HPV Infection; HPV in External Skin; Anogenital Warts; Laryngeal Papillomatosis; Common Warts of Hands and Face; Plantar Warts; Epidermodysplasia Verruciformis; Persistence and Malignant Conversion of Cutaneous Warts; HPV in Mucosal and Anogenital Skin; Systemic Lupus Erythematosus; HPV Associated Anogenital Pre-Cancers and Cancers; CONCLUDING REMARKS; CONFLICT OF INTEREST; ACKNOWLEDGEMENT; REFERENCES; The Life Cycle and Transmission of HPV Types.
  • Kimia Kardani, Niloofar Naderi and Azam Bolhassani*INTRODUCTION; Life Cycle of HPV; Maintenance of the Viral Genome and Cell Proliferation in the Lower Epithelial Layers; Genome Maintenance and Proliferation in the Upper Epithelial Layers; Virus Packaging and Release; Cancer Progression; Lesion Regression and Clearance; Papillomavirus Interaction with Cellular Chromatin; Episome Maintenance in Proliferating Basal Epithelial Cells; CONCLUDING REMARKS; CONFLICT OF INTEREST; ACKNOWLEDGEMENT; REFERENCES; Natural History of HPV Infections in Cancer Development.
  • Niloofar Naderi, Kimia Kardani and Azam Bolhassani*INTRODUCTION; Natural History of HPV-Related Neoplasia; Risk of CIN3+ Following a Positive HPV Test; Risk of CIN3+ Following a Negative HPV Test; Non-Viral Co-factors for HPV Persistence; Natural History of CIN2; Anal HPV Natural History in Men and Women; CONCLUDING REMARKS; CONFLICT OF INTEREST; ACKNOWLEDGEMENT; REFERENCES; HPV-Related Cancers; Kimia Kardani and Azam Bolhassani*; INTRODUCTION; Cervical Cancer; Anal Cancer; Head and Neck Cancer; Penile Cancer; Vaginal Cancer; Vulvar Cancer; Adenocarcinoma of Uterine Cervix; Ovarian Cancer.