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Tabla de Contenidos:
  • PREFACE; List of Contributors; Mesenchymal Stem Cells and Biomaterials for Cartilage Repair in Vivo with a Focus on Gene Therapy; Ana Rey-Rico, Janina Frisch and Magali Cucchiarini*; INTRODUCTION; ARTICULAR CARTILAGE; Structure; Injuries; Therapeutic Options; MESENCHYMAL STEM CELLS FOR CARTILAGE REPAIR; Definition; Endochondral Ossification; IN VIVO APPLICATIONS OF MSCS FOR CARTILAGE REPAIR; General Aspects; MSC Transplantation; Administration of MSCs via Biodegradable Scaffolds; ECM-derived Compounds; Natural Compounds; Hydrogels; Solid Scaffolds; Multiphasic Scaffolds.
  • Tissue Engineering and Gene Therapy as Combined Option for MSC ImplantationGenetic Modification of MSCs; Administration of Genetically Modified MSCs via Biodegradable Scaffolds; SUMMARY AND CONCLUSION; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Consequences of Inflammation within Neural Stem Cell Niches on Development and Regeneration; Stephanie Veerasammy, Ekta Kumari, Matthew T. Goodus, Eric J. Neuberger, Vijayalakshmi Santhakumar and Steven W. Levison*; INTRODUCTION; INFECTIONS AND PERINATAL BRAIN DEVELOPMENT.
  • Maternal Immune Activation, Chorioamnionitis and the Fetal Inflammatory ResponsePostnatal Neurogenesis in the Hippocampus; EFFECTS OF INFLAMMATION ON THE ENDOGENOUS STEM CELLS AND PROGENITORS OF THE DEVELOPING HIPPOCAMPUS; Interleukin-1 and Hippocampal Neurogenesis; The IL-1β-induced Systemic Inflammation Model in Neonatal Mice; Interleukin-6 and Hippocampal Neurogenesis; Vascular Endothelial Growth Factor and Hippocampal Neurogenesis; EFFECTS OF INFLAMMATION ON ENDOGENOUS STEM CELLS AND PROGENITORS IN THE SVZ; Maternal IL-6 Levels Affect Embryonic SVZ Neurogenesis.
  • IL-6 has a Different Role in Adult NeurogenesisIL-1β and SVZ Neurogenesis; VEGFs and SVZ Neurogenesis; Transforming Growth Factor-β 1 and SVZ Neurogenesis; IFNγ: A Negative Regulator of SVZ Neurogenesis; IFNγ Regulates Proliferation and Neuronal Differentiation by STAT1 in the SVZ; BDNF Affects SVZ Neurogenesis Through Nitric Oxide Production; Prostaglandins and SVZ Neurogenesis; EFFECTS OF NEONATAL H-I ON STEM CELLS AND PROGENITORS IN THE NEONATAL AND ADOLESCENT SVZ; Role of IL-6 in Neonatal H-I Induced Expansion of Neural Progenitors in the SVZ.
  • TGFÎ#x91; IN H-I INDUCED EXPANSION OF NEURAL PROGENITORS IN THE SVZVEGFs A and C in Neonatal H-I; TNF-α in H-I Induced Expansion of Neural Progenitors in the SVZ; EFFECTS OF TRAUMATIC BRAIN INJURIES ON STEM CELLS AND PROGENITORS IN THE NEONATAL AND ADOLESCENT SVZ; Age-Related Differences in SVZ Responses to Brain Injury; CONCLUDING THOUGHTS; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Cell-based Therapeutic Strategies for Treatment of Liver Diseases; Laia Tolosa1,2, Maria José Gómez-Lechón1,2,3 and Eugenia Pareja1,4,*; INTRODUCTION.