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|a 995357828
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|a UAMI
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|a Montgomery, Marion.
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| 245 |
1 |
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|a Triple-Negative Breast Cancer.
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| 260 |
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|a Hauppauge :
|b Nova Science Publishers, Inc.,
|c 2017.
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| 300 |
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|a 1 online resource (132 pages)
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| 336 |
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|a text
|b txt
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|a online resource
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1 |
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|a Cancer Etiology, Diagnosis and Treatments
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|a Print version record.
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|a Preface; Chapter 1; The Role of Exosomes in Breast Cancer: What Have We Learned in Ten Years?; Abstract; Introduction; Exosomes: An Overview; Exosomes: In Cancer; Cancer-Associated Exosomes Containing Proteins; Cancer-Associated Exosomes Containing Nucleic Acids; miRNA-containing Exosomes; mRNA-Containing Exosomes; DNA-containing Exosomes; Cancer-Associated Exosomes Containing Lipids; Exosomes in the Breast Tumor Microenvironment; Exosomes in Hypoxia, Epithelial -- Mesenchymal Transition, ROS Production and Autophagy; Exosomes in Metastasis; Exosomes and Drug Resistance.
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| 505 |
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|a Conclusion and Future PerspectivesReferences; Chapter 2; Correlations between BRCA Gene Mutations and the High Risk of TNBC as Defined by the Defect of Estrogen Signaling; Abstract; Introduction; Interplay Between Endogenous Estrogens and Wild-Type BRCA Genes; Correlations between BRCA Gene Mutations and Defective Estrogen Signaling; Decreased ER-Alpha Expression in BRCA Gene Mutation Carrier Cells; Decreased Estradiol-Liganded Transcriptional Activity of ERs in BRCA Gene Deficient Cells; Defensive Counteractions Against BRCA Gene Defects.
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| 505 |
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|a Increased Aromatase Activity Associated with BRCA Gene MutationHyperestrogenism as a Compensatory Mechanism in Women with BRCA Gene Mutation; Increased Ligand-Independent Transcriptional Activity in Cells with BRCA1 Mutation; Hormonal Risk Factors for Overall Breast Cancer and TNBC; Correlations between Menopausal Status and TNBC Risk; Correlations between Reproductive History and the Risk of Different Breast Cancer Subtypes; Conclusion; References; Chapter 3; The Role of Tumor Infiltrating Lymphocytes (TILs) in Triple Negative Breast Cancer (TNBC); Abstract; Introduction.
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| 505 |
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|a Pathologic and Molecular Heterogeneity of TNBCTumor-Infiltrating Lymphocytes in TNBC; a. TILs as a Prognostic Factor; b. TILs as a Predictive Factor; c. TILs as Biomarkers of Residual Disease; Targeting the Immune System in Triple-Negative Breast Cancer: Potential Role of the PD-1/PD-L1 Pathway as a Biomarker; Conclusion; References; Index; Blank Page.
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| 504 |
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|a Includes bibliographical references and index.
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| 590 |
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|a eBooks on EBSCOhost
|b EBSCO eBook Subscription Academic Collection - Worldwide
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| 650 |
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0 |
|a Breast
|x Cancer.
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| 650 |
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2 |
|a Breast Neoplasms
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| 650 |
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6 |
|a Sein
|x Cancer.
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| 650 |
|
7 |
|a HEALTH & FITNESS
|x Diseases
|x General.
|2 bisacsh
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| 650 |
|
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|a MEDICAL
|x Clinical Medicine.
|2 bisacsh
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|a MEDICAL
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|a MEDICAL
|x Evidence-Based Medicine.
|2 bisacsh
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|a MEDICAL
|x Internal Medicine.
|2 bisacsh
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| 650 |
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|a Breast
|x Cancer.
|2 fast
|0 (OCoLC)fst00838260
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|i Print version:
|a Montgomery, Marion.
|t Triple-Negative Breast Cancer: Biomarkers, Emerging Therapeutic Strategies and Clinical Challenges.
|d Hauppauge : Nova Science Publishers, Inc., ©2017
|z 9781536123722
|
| 830 |
|
0 |
|a Cancer etiology, diagnosis, and treatments.
|
| 856 |
4 |
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