Horizons in cancer research. Volume 68 /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Watanbe, Hiroto S. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : Nova Biomedical, 2017.
Temas:
Cancer > Research.
Cancer > Treatment.
Cancer > Recherche.
Cancer > Traitement.
HEALTH & FITNESS > Diseases > General.
MEDICAL > Clinical Medicine.
MEDICAL > Diseases.
MEDICAL > Evidence-Based Medicine.
MEDICAL > Internal Medicine.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Preface; Chapter 1; Multimodal Treatment of High Grade Glioma; Federico Caporlingua1,*, MD, Alessandro Caporlingua1, MD, Alessandra Marongiu2, MD, Maria Pia Tropeano1, MD and Maurizio Salvati3; 1. Epidemiology; 2. Imaging of HGG; 3. Molecular Classification and Implications for Personalized Therapy in Glioma; 3.1. GBM Classification; 3.1.1. Primary versus Secondary GBM; 3.1.2. GBM Subtypes Based on Molecular Profiling; 3.2. Genetic and Epigenetic Mutations; 3.2.1. IDH1 and IDH2 Mutations; 3.2.2. O6-Methylguanine-DNA Methyltransferase (MGMT) Methylation
  • 3.2.3. Detection of 1p/19q Co-DeletionSurgical Treatment; 4.1. Surgery in the Elder Patient; 4.2. Surgical Management of Recurrences; 5. Principles of Chemotherapy and Radiotherapy; 5.1. Limitations of Chemotherapy; 5.2. Pharmacology of Commonly Used Agents; 5.2.1. Alkylating Agents; Temozolomide; Nitrosoureas; 5.2.2. Alkaloids; Vincristine; 5.2.3. Topoisomerase Inhibitors; Etoposide; 6. Epilepsy in HHGs; 6.1. Management of Epileptic Seizures in HGG; 6.1.1. Surgery; 6.1.2. Radiotherapy and Chemotherapy; 7. Future Scenarios; Conclusion; References; Chapter 2
  • Metastasis Suppressor Genes: Function and RegulationPatricio Barros-Núñez, Mónica Alejandra Rosales-Reynoso and Sofía Dumois-Petersen; Abstract; Introduction; Metastasis Development; Dissociation Phase; Invasion Phase; Intravasation Phase; Survival in Circulation Phase; Extravasation Phase; Dormancy Phase; Metastasis Suppression; Metastasis Suppressor Genes; Membrane-Bound Metastasis Suppressors; Nuclear Metastasis Suppressor Genes; Cytoplasmic Metastasis Suppressor Genes; Epigenetic Mechanisms and Metastasis Suppressor Genes; Clinical Implications; References; Chapter 3
  • Pineal Gland Secretion: The Regulation and Therapeutic Role in CancerMunibah Qureshi, Armughan Haider and Adeeb Shehzad*; Abstract; 1. Introduction; 1.1. Pineal Gland; 1.2. Anatomy; 1.3. Histology; 1.4. Innervations; 1.4.1. Sympathetic Innervations; 1.4.2. Non-Sympathetic Innervation of Pineal Gland; 1.4.3. Parasympathetic Innervations of Pineal Gland; 1.4.4. Trigeminal Ganglion; 1.5. Function of Pineal Body; 2. Secretion: Melatonin, Synthesis and Regulation; 2.1. Synthesis; 2.2. Regulation; 2.3. Elimination; 3. Therapeutic Implications; 3.1. Melatonin Therapeutic Role in Cancer
  • ConclusionReferences; Chapter 4; Oncolytic Virotherapies in Thoracic Cancers; Zeeshan Ahmad and Robert A. Kratzke*; Abstract; Introduction; Viral Targeting of Tumor Cells; Development of Attenuated Viruses; Oncolytic Viruses Induce Intrinsic Apoptosis in Cancer Cells; Oncolytic Virotherapy Combined with Immunotherapy; Oncolytic Virotherapy in Malignant Pleural Mesothileoma; Measles Virus; Measles-Induced Immune Suppression; Role of Dendritic Cells in Cancer Immunetherapy; Role of Type I Interferons; Sodium Ion Symporter; Newcastle Disease Virus; Oncolyic Virotherapy in Lung Cancer

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