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Horizons in cancer research. Volume 66 /
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York :
Nova Science Publishers, Inc.,
2017.
|
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Preface; Chapter 1; Chronic Myeloid Leukemia: Diagnosis, Treatment Options and Clinical Approaches; Abstract; Introduction; Clinical and Laboratory Features; Disease Evolution; Molecular Pathogenesis; Diagnosis; Treatment Options; Disease Monitoring; Hematologic Responses; Cytogenetic Responses; Molecular Responses; Definition of Clinical Response and Withholding of TKI Therapy; TKI Resistance and Mutational Analysis; References; Biographical Sketches; Chapter 2; Self-Esteem and Social Relationships in Preadolescents and Adolescents Who Survived Pediatric Leukemia; Abstract.
- 1. Introduction1.1. Theoretical Framework; 1.2. Self-Esteem and Social Relationships in Childhood Cancer Survivors; 1.3. Study Aims and Hypothesis; 2. Method; 2.1. Participants; 2.2. Procedure; 2.3. Instruments; 2.3.1. Multidimensional Self-Esteem Test (TMA, Bracken, 1992; Italian version Mazzeo, 2003); 2.3.2. Ecocultural-Family Interview-Cancer, Pediatric Cancer Survivors' Version; 2.3.3. SES Questionnaire; 3. Results; 3.1. Self-Esteem Scoring, Present Well-being and Social Relationships in Preadolescents and Adolescents.
- 3.2. Associations between Self-Esteem Scoring and Illness Variables3.3. Associations between dimensions of EFI-C Pediatric Cancer Survivors' Version with Self-Esteem Scoring; 4. Discussion; References; Chapter 3; The Role of Lactoferrin Expression in Initiation and Progression of Most Common Hormone-Dependent Cancers; Abstract; Abbreviations; Introduction; Study of LF Expression in Benign and Malignant Breast and Prostate Tumors; Relationship between LF Expression in Benign and Malignant Breast Tumors Based on Clinical and Pathological Features of the Tumor Progression.
- LF Expression in Malignant and Benign Prostate Tumor TissuesConclusion; References; Chapter 4; ETS Transcription Factor FLI-1 as an Important Player in Human Cancer; Abstract; Introduction; Friend Leukemia Integration-1 (Fli-1); Fli-1 Target Genes; The Role of Fli-1 in Malignant Transformation; Fli-1 Inhibitors; Increased Level of Fli-1 Messenger RNA in Bone Marrow and Blood Mononuclear Cells of MDS Patients with 5q- Syndrome; Increased FLI-1 Transcriptional Activity can Inhibit Tumor Growth in Erythroleukemia and Probably Some Other Cancers; Conclusion and Perspectives; Acknowledgments.
- Conflict of InterestReferences; Chapter 5; From DNA Methylation Signature in Circulating DNA to Cancer Detection and Monitoring; Abstract; 1. Introduction; 2. Circulating Tumor Cells and Cell-Free Tumor DNA; 3. The Utility of DNA Methylation Signature as a Tumor Biomarker; 3.1. Tumor-Specific Gene Methylations; 4. Analytical Methods; 5. DNA Methylation Biomarkers in ctDNA for Clinical Use; 5.1. Cancer Screening and Early Detection; 5.2. Prediction of Response to Chemotherapy; 5.2.1. Therapies with Demethylating Drugs; 5.3. Determination of Prognosis; 6. Future Perspective; References.