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Prions and prion diseases : new developments /
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York :
Nova Biomedical/Nova Science Publishers, Inc.,
[2012]
|
| Colección: | Protein biochemistry, synthesis, structure, and cellular functions series.
Protein science and engineering. |
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 003 | OCoLC | ||
| 005 | 20231017213018.0 | ||
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| 008 | 111223s2012 nyu ob 001 0 eng | ||
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| 082 | 0 | 0 | |a 573.8/639929 |2 23 |
| 049 | |a UAMI | ||
| 245 | 0 | 0 | |a Prions and prion diseases : |b new developments / |c Jean-Michel Verdier, editor. |
| 264 | 1 | |a New York : |b Nova Biomedical/Nova Science Publishers, Inc., |c [2012] | |
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Protein biochemistry, synthesis, structure, and cellular functions | |
| 490 | 1 | |a Protein science and engineering | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 505 | 0 | |a PRIONS AND PRION DISEASES -- PRIONS AND PRION DISEASES -- CONTENTS -- PREFACE -- NEUROPATHOLOGY OF HUMAN PRION DISEASES -- ABSTRACT -- INTRODUCTION -- THE ROLE OF NEUROPATHOLOGY -- PERFORMING THE AUTOPSY -- NEUROPATHOLOGICAL EXAMINATION -- A.) Macroscopy -- B.) Work-Up for Histological Evaluation -- C.) Microscopic Assessment -- I.) Spongiform Change of the Neuropil -- a) In Sporadic Forms -- b.) In Genetic Forms -- c.) In Acquired Forms -- II) Neuronal Death -- a.) In Sporadic Forms -- b.) In Genetic Forms -- c.) In Acquired Forms | |
| 505 | 8 | |a SYNAPTIC PATHOLOGY III.) Astroglial Proliferation -- IV.) Microglial Activation -- V.) PrP Amyloid Plaques -- a.) In Sporadic Forms -- b.) In Genetic Forms -- c.) In Acquired Forms -- VI.) Cerebellar Pathology -- a.) In Sporadic Forms -- b.) In Genetic Forms -- c.) In Acquired Forms -- RELATIVE RESISTANCE OF HIPPOCAMPUS IN CJD -- VII.) Detection of PrP -- VIIa.) By Immunohistochemistry -- a.) In Sporadic Forms -- b.) In Genetic Forms -- c.) In Acquired Forms -- VIIb.) By histoblot and Paraffin-Embedded Tissue Blot | |
| 505 | 8 | |a VIId.) By Western blota.) In Sporadic Forms -- b.) In Genetic Forms -- c.) In Acquired Forms -- VIII.) Co-deposition of other Abnormal Protein Aggregates in CJD -- a) In Sporadic Forms -- b) In Genetic Forms -- c) In Acquired Forms -- IX.) Differential Diagnoses from Autopsy Series -- X.) Neuronal Systems and Their Clinico-Pathological Correlates -- CONCLUSION -- ACKNOWLEDGMENTS -- REFERENCES -- THE NATURE OF THE INFECTIOUS AGENTS: PRP MODELS OF RESISTANT SPECIES TO PRION DISEASES (DOG, RABBIT AND HORSES) -- Abstract -- 1. Introduction | |
| 505 | 8 | |a 2. MaterialsandMethods3. ResultsandDiscussion -- 4. Conclusion -- Acknowledgments -- References -- INDUCING TRANSMISSIBLE PRION DISEASES WITH RECOMBINANT FIBRILS: A NEW CONCEPT ON GENESIS AND EVOLUTION OF INFECTIOUS PRIONS -- ABSTRACT -- GENERATING TRANSMISSIBLE PRION DISEASES DE NOVO -- THE MECHANISM OF TRIGGERING PRION DISEASE BY RPRP AMYLOID FIBRILS -- EXPERIMENTAL EVIDENCE SUPPORT THE SECOND MODEL -- THE HYPOTHESIS OF DEFORMED TEMPLATING -- CONFORMATIONAL SWITCHING WITHIN INDIVIDUAL AMYLOID FIBRILS AND STRAIN ADAPTATION PHENOMENON | |
| 505 | 8 | |a CROSS-TALK BETWEEN AMYLOIDOGENIC PROTEINS REFERENCES -- SYNTHETIC PRIONS -- ABSTRACT -- 1. INTRODUCTION -- 2. STRATEGIES FOR DE NOVO MAMMALIAN PRIONS GENERATION -- 2.1. Cell-Free Assay Using Mammalian Prions -- 2.2. De Novo Generation of Prions by Mouse Transgenesis -- 2.3. In Vitro De Novo Prions by PMCA -- 2.4. De Novo Prions by Amyloid Seeding Assay -- 2.5. De Novo Prions by Annealing Technique -- 2.6. Concluding Remarks and New Emerging Techniques for Prion Detection and Generation -- 3. STRUCTURAL BIOLOGY OF NATURAL AND SYNTHETIC PRIONS | |
| 546 | |a English. | ||
| 590 | |a eBooks on EBSCOhost |b EBSCO eBook Subscription Academic Collection - Worldwide | ||
| 650 | 0 | |a Prions. | |
| 650 | 0 | |a Prion diseases. | |
| 650 | 6 | |a Prions (Virologie) | |
| 650 | 6 | |a Maladies à prions. | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Biology. |2 bisacsh | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Microbiology. |2 bisacsh | |
| 650 | 7 | |a Prion diseases. |2 fast |0 (OCoLC)fst01076975 | |
| 650 | 7 | |a Prions. |2 fast |0 (OCoLC)fst01076986 | |
| 700 | 1 | |a Verdier, Jean-Michel, |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Prions and prion diseases. |d New York : Nova Biomedical/Nova Science Publishers, Inc., [2012] |z 9781621000273 |w (DLC) 2011946079 |
| 830 | 0 | |a Protein biochemistry, synthesis, structure, and cellular functions series. | |
| 830 | 0 | |a Protein science and engineering. | |
| 856 | 4 | 0 | |u https://ebsco.uam.elogim.com/login.aspx?direct=true&scope=site&db=nlebk&AN=541053 |z Texto completo |
| 938 | |a ProQuest Ebook Central |b EBLB |n EBL3017951 | ||
| 938 | |a ebrary |b EBRY |n ebr10654922 | ||
| 938 | |a EBSCOhost |b EBSC |n 541053 | ||
| 938 | |a YBP Library Services |b YANK |n 7422494 | ||
| 994 | |a 92 |b IZTAP | ||