|
|
|
|
| LEADER |
00000cam a2200000 i 4500 |
| 001 |
EBSCO_ocn960906126 |
| 003 |
OCoLC |
| 005 |
20231017213018.0 |
| 006 |
m o d |
| 007 |
cr ||||||||||| |
| 008 |
161017s2016 nyu ob 001 0 eng |
| 010 |
|
|
|a 2016047714
|
| 040 |
|
|
|a DLC
|b eng
|e rda
|c DLC
|d N$T
|d OCLCF
|d EBLCP
|d SNK
|d DKU
|d AUW
|d INTCL
|d IGB
|d D6H
|d VTS
|d AGLDB
|d G3B
|d S8J
|d S9I
|d STF
|d DLC
|d OCLCO
|d YDX
|d OCLCO
|d OCLCQ
|
| 019 |
|
|
|a 965737418
|
| 020 |
|
|
|a 9781536102611
|q (ebk)
|
| 020 |
|
|
|a 153610261X
|
| 020 |
|
|
|z 9781536102444
|q (hardcover)
|
| 020 |
|
|
|z 153610244X
|
| 029 |
1 |
|
|a AU@
|b 000058859084
|
| 035 |
|
|
|a (OCoLC)960906126
|z (OCoLC)965737418
|
| 042 |
|
|
|a pcc
|
| 050 |
1 |
0 |
|a QP624.5.M46
|
| 060 |
|
4 |
|a QU 58.5
|
| 072 |
|
7 |
|a SCI
|x 007000
|2 bisacsh
|
| 082 |
0 |
0 |
|a 572.8/6
|2 23
|
| 049 |
|
|
|a UAMI
|
| 245 |
0 |
0 |
|a DNA methylation :
|b patterns, functions and roles in disease /
|c Kathleen Holland, editor.
|
| 264 |
|
1 |
|a New York :
|b Nova Biomedical,
|c [2016]
|
| 300 |
|
|
|a 1 online resource.
|
| 336 |
|
|
|a text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a computer
|b c
|2 rdamedia
|
| 338 |
|
|
|a online resource
|b cr
|2 rdacarrier
|
| 490 |
1 |
|
|a Genetics - research and issues
|
| 504 |
|
|
|a Includes bibliographical references and index.
|
| 588 |
|
|
|a Description based on print version record and CIP data provided by publisher.
|
| 505 |
0 |
|
|a Preface; Chapter 1; Disruption of DNA Methylation Patterns Caused by Exposure to Environmental Factors during the Developmental Period; Abstract; Introduction; Endocrine-Disrupting Chemicals; Heavy Metals; Particulate Matter; Food and Alcohol Intake; Cigarette Smoke; Possible Mechanism of Dysregulation of DNA Methylation; Conclusion; Acknowledgments; References; Chapter 2; Cytosine Modifications Affect Biological Significance by a Multifactorial Network; Abstract; Abbreviations; 1. Introduction; 2. Structures of Cytosine Modifications and Active Demethylation Process
|
| 505 |
8 |
|
|a 3. Classification of DNA Methylation in Terms of Genetic Materials and Genomic Regions3.1. Nucleic Acid Type; 3.1.1. Nuclear DNA Methylation; 3.1.2. Organelle DNA Methylation; 3.1.3. RNA Methylation; 3.2. Cytosine-Guanine (CpG) Repeats; 3.2.1. CpG Content; 3.2.2. CpG Islands; 3.3. Intergenic Locations; 4. 3D DNA Structure and Interaction with Methylation; 5. Chemical Characteristics of DNA and Its Relation with Methylation; 6. Proteins Binding to Methylated DNA; 6.1. Methylated DNA-Specific Proteins; 6.1.1. MBD Proteins; 6.1.2. Kaiso-Like Zinc Finger Protein Group
|
| 505 |
8 |
|
|a 6.1.3. Set and Ring Finger-Associated (SRA) Domain Proteins6.2. Relationship between Methyl-Binding Proteins and DNA Methylation in Different Genomic Regions; 6.3. Histones; 6.4. Transcription Factors; 7. Biological Significance of Cytosine Modifications; 7.1. In Eukaryotes; 7.2. In Prokaryotes; Conclusion; References; Biographical Sketch; Chapter 3; Targeting Aberrant IGF2 Epigenetics as a Novel Anti-Tumor Approach; Abstract; Introduction; Loss of IGF2 Imprinting as a Molecular Hallmark in Tumors; Epigenetic Mechanisms Underlying Loss of IGF2 Imprinting in Tumors
|
| 505 |
8 |
|
|a Correction of Aberrant Imprinting by Polycomb Repressive Complex 2 Docking Factor SUZ12An Oncolytic Viral Therapy Using the IGF2/H19 Enhancer-Insulator-Promoter System; Conclusion; Acknowledgments; References; Bibliography; Related Nova Publications; DNA Methylation: Principles, Mechanisms and Challenges; Global DNA Methylation in Obesity, Diabetes and Cardiovascular Diseases and the Influence of Environmental Factors*; The Link between MTHFR C677T Polymorphism, Folate Metabolism and Global DNA Methylation: A Literature Review*
|
| 505 |
8 |
|
|a The Role of DNA Methylation in the Genetics and Epigenetics of Multiple Myeloma*Detecting DNA Methylation for Cancer Diagnostics and Prognostics*; Index
|
| 590 |
|
|
|a eBooks on EBSCOhost
|b EBSCO eBook Subscription Academic Collection - Worldwide
|
| 650 |
|
0 |
|a DNA
|x Methylation.
|
| 650 |
|
2 |
|a DNA Methylation
|
| 650 |
|
6 |
|a ADN
|x Méthylation.
|
| 650 |
|
7 |
|a SCIENCE
|x Life Sciences
|x Biochemistry.
|2 bisacsh
|
| 650 |
|
7 |
|a DNA
|x Methylation.
|2 fast
|0 (OCoLC)fst00886570
|
| 700 |
1 |
|
|a Holland, Kathleen Mary,
|e editor.
|
| 776 |
0 |
8 |
|i Print version:
|t DNA methylation : patterns, functions and roles in disease
|d New York : Nova Biomedical, [2016]
|z 9781536102444
|w (DLC) 2016043773
|
| 830 |
|
0 |
|a Genetics--research and issues series.
|
| 856 |
4 |
0 |
|u https://ebsco.uam.elogim.com/login.aspx?direct=true&scope=site&db=nlebk&AN=1406307
|z Texto completo
|
| 938 |
|
|
|a EBSCOhost
|b EBSC
|n 1406307
|
| 938 |
|
|
|a ProQuest Ebook Central
|b EBLB
|n EBL4743747
|
| 938 |
|
|
|a YBP Library Services
|b YANK
|n 13188061
|
| 994 |
|
|
|a 92
|b IZTAP
|
