Aminoglycosides : pharmacology, clinical uses and health effects /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Alves, Ruthie (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : Nova Biomedical, [2016]
Colección:Pharmacology-research, safety testing, and regulation series.
Temas:
Aminoglycosides.
Aminoglycosides
Aminosides.
MEDICAL > Pharmacology.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Preface; Chapter 1; Amphiphilic Analogues of Aminoglycosides as Antitubercular and Antimicrobial Agents; Abstract; 1. Introduction; 1.1. Background; 1.2. Drug Resistant Tuberculosis; 1.3. Tuberculosis Chemotherapy; 1.4. The DOTS Treatment Regimen; 1.5. Aminoglycosides; 1.6. Aminoglycoside Structure; 1.7. Bacterial Uptake of Aminoglycosides; 1.8. Molecular Mechanism of Action; 1.9. Mechanisms of Resistance; (i) Reduction of the Intracellular Drug Concentration
  • A Result of Reduced Permeability or Action of Efflux Pumps; (ii) Spontaneous Mutation of the Ribosomal Target.
  • (Iii) Modification of the Antibiotic by Aminoglycoside Modifying Enzymes (AMEs)2. Amphiphilic Aminoglycosides; 2.1. Neomycin; 2.2. Tobramycin; 2.3. Neamine; 2.4. Paromomycin; 2.5. Kanamycin; 2.6. Amikacin; 2.7. Netilmicin and Sisomicin; 2.8. Nebramine; 2.9. Arbekacin; Conclusion; References; Chapter 2; Aminoglycoside Use in Patients with Chronic Kidney Disease; Abstract; Introduction; Pharmacology; Pharmacokinetics; Mechanism of Action; Aminoglycoside Toxicity; Post-Antibiotic Effect; Adaptive Resistance; Key Points; Dosing, Monitoring and Clearance in Chronic Kidney Disease.
  • Dosing and FormulaeMonitoring Aminoglycoside Levels; Inhaled Aminoglycosides; Key Points; Dosing, Monitoring and Clearance in Haemodialysis; Intermittent Haemodialysis; Continuous and Extended Dialysis Modalities; Aminoglycoside Catheter Locks; Key Points; Dosing, Monitoring and Clearance in Peritoneal Dialysis; Intraperitoneal Antibiotics; Topical Aminoglycosides for Exit Sites; Key Points; Conclusion; References; Chapter 3; Partial or Complete Vestibular Recovery Is Related to the Presence of mitDNA Specific Polymorphisms in Aminoglycoside Antibiotic Treated Female Patients.
  • 1Division of Neurosciences and Molecular Biology Unit, Institute of Cellular Physiology, National Autonomous University of Mexico, Mexico City, Mexico2Audiology and Otoneurology Service, Hospital Angeles de las Lomas, Mexico, DF, Mexico; 3Building A-6, Department 102, Torres de Mixcoac, ; México, D.F. México; Abstract; Introduction; Material and Methodology; Results; Discussion; Conclusion; Acknowledgments; References; Commentary; Gentamicin-Induced Nephrotoxicity: Sesame Oil as a Potential; Protective Agent; References; Related Nova Publications.
  • Use of Natural Products to Enhance the Antibiotic Activity of Gentamicin and Other Aminoglycosides: The Future of Antibiotictherapy*2Department of Biological Chemistry, Regional University of Cariri, Crato, CE, Brazi; Bibliography; Index.

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