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EBSCO_ocn960870871 |
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160901s2016 nyua ob 001 0 eng |
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|a 2020688124
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|z 9781536101805
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|2 23
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|a UAMI
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|a Aminoglycosides :
|b pharmacology, clinical uses and health effects /
|c Ruthie Alves, editor.
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|a New York :
|b Nova Biomedical,
|c [2016]
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| 300 |
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|a 1 online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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|a computer
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| 338 |
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|a online resource
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|a data file
|2 rda
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|a Pharmacology-research, safety testing, and regulation
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|a Includes bibliographical references (pages [97]-102) and index.
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|a Description based on print version record and CIP data provided by publisher.
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|a Preface; Chapter 1; Amphiphilic Analogues of Aminoglycosides as Antitubercular and Antimicrobial Agents; Abstract; 1. Introduction; 1.1. Background; 1.2. Drug Resistant Tuberculosis; 1.3. Tuberculosis Chemotherapy; 1.4. The DOTS Treatment Regimen; 1.5. Aminoglycosides; 1.6. Aminoglycoside Structure; 1.7. Bacterial Uptake of Aminoglycosides; 1.8. Molecular Mechanism of Action; 1.9. Mechanisms of Resistance; (i) Reduction of the Intracellular Drug Concentration -- A Result of Reduced Permeability or Action of Efflux Pumps; (ii) Spontaneous Mutation of the Ribosomal Target.
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|a (Iii) Modification of the Antibiotic by Aminoglycoside Modifying Enzymes (AMEs)2. Amphiphilic Aminoglycosides; 2.1. Neomycin; 2.2. Tobramycin; 2.3. Neamine; 2.4. Paromomycin; 2.5. Kanamycin; 2.6. Amikacin; 2.7. Netilmicin and Sisomicin; 2.8. Nebramine; 2.9. Arbekacin; Conclusion; References; Chapter 2; Aminoglycoside Use in Patients with Chronic Kidney Disease; Abstract; Introduction; Pharmacology; Pharmacokinetics; Mechanism of Action; Aminoglycoside Toxicity; Post-Antibiotic Effect; Adaptive Resistance; Key Points; Dosing, Monitoring and Clearance in Chronic Kidney Disease.
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|a Dosing and FormulaeMonitoring Aminoglycoside Levels; Inhaled Aminoglycosides; Key Points; Dosing, Monitoring and Clearance in Haemodialysis; Intermittent Haemodialysis; Continuous and Extended Dialysis Modalities; Aminoglycoside Catheter Locks; Key Points; Dosing, Monitoring and Clearance in Peritoneal Dialysis; Intraperitoneal Antibiotics; Topical Aminoglycosides for Exit Sites; Key Points; Conclusion; References; Chapter 3; Partial or Complete Vestibular Recovery Is Related to the Presence of mitDNA Specific Polymorphisms in Aminoglycoside Antibiotic Treated Female Patients.
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|a 1Division of Neurosciences and Molecular Biology Unit, Institute of Cellular Physiology, National Autonomous University of Mexico, Mexico City, Mexico2Audiology and Otoneurology Service, Hospital Angeles de las Lomas, Mexico, DF, Mexico; 3Building A-6, Department 102, Torres de Mixcoac, ; México, D.F. México; Abstract; Introduction; Material and Methodology; Results; Discussion; Conclusion; Acknowledgments; References; Commentary; Gentamicin-Induced Nephrotoxicity: Sesame Oil as a Potential; Protective Agent; References; Related Nova Publications.
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|a Use of Natural Products to Enhance the Antibiotic Activity of Gentamicin and Other Aminoglycosides: The Future of Antibiotictherapy*2Department of Biological Chemistry, Regional University of Cariri, Crato, CE, Brazi; Bibliography; Index.
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|a Aminoglycosides.
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|a Alves, Ruthie.
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|t Aminoglycosides
|d New York : Nova Biomedical, 2016.
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