Cargando…
A prescription for change : the looming crisis in drug development /
The introduction of new medicines has dramatically improved the quantity and quality of individual and public health while contributing trillions of dollars to the global economy. In spite of these past successes -- and indeed because of them -- our ability to deliver new medicines may be quickly co...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Chapel Hill :
The University of North Carolina Press,
2016.
|
| Colección: | Luther H. Hodges, Jr. and Luther H. Hodges, Sr. series on business, entrepreneurship, and public policy.
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
| LEADER | 00000cam a2200000 a 4500 | ||
|---|---|---|---|
| 001 | EBSCO_ocn959609251 | ||
| 003 | OCoLC | ||
| 005 | 20231017213018.0 | ||
| 006 | m o d | ||
| 007 | cr |n||||||||| | ||
| 008 | 160930s2016 ncu ob 001 0 eng d | ||
| 040 | |a IDEBK |b eng |e pn |c IDEBK |d N$T |d JSTOR |d OCLCF |d ANG |d IDEBK |d OCLCQ |d EBLCP |d HV6 |d I3U |d YDX |d MERUC |d OCLCO |d P@U |d OCLCA |d WTU |d UAB |d DGU |d MYG |d VGM |d OTZ |d OCLCQ |d IGB |d IOG |d OCLCO |d AGLDB |d OCLCO |d CUS |d OCLCA |d D6H |d SGB |d STF |d OCLCQ |d VTS |d OCLCA |d WYU |d OCLCQ |d S9I |d TKN |d JBG |d OCLCQ |d OCLCO |d OCLCQ |d OCLCA |d VLY |d AJS |d OCLCA |d HUL |d OCLCO |d BIBBD |d OCLCO |d OCL |d INARC |d OCLCQ |d SFB |d OCLCQ |d TEFOD |d OCLCO | ||
| 019 | |a 960759013 |a 962125311 |a 966742721 |a 1162490948 |a 1241801512 | ||
| 020 | |a 1469630648 |q (electronic bk.) | ||
| 020 | |a 9781469630649 |q (electronic bk.) | ||
| 020 | |a 9781469630632 |q (electronic bk.) | ||
| 020 | |a 146963063X |q (electronic bk.) | ||
| 020 | |z 1469630621 | ||
| 020 | |z 9781469630625 | ||
| 029 | 1 | |a AU@ |b 000058946938 | |
| 029 | 1 | |a AU@ |b 000074150531 | |
| 035 | |a (OCoLC)959609251 |z (OCoLC)960759013 |z (OCoLC)962125311 |z (OCoLC)966742721 |z (OCoLC)1162490948 |z (OCoLC)1241801512 | ||
| 037 | |a 951907 |b MIL | ||
| 037 | |a 22573/ctt1bnjx1n |b JSTOR | ||
| 037 | |a 19D8A5F7-651D-4285-B193-A724533E82D9 |b OverDrive, Inc. |n http://www.overdrive.com | ||
| 050 | 4 | |a RM301.25 |b .K55 2016eb | |
| 060 | 4 | |a QV 745 | |
| 072 | 7 | |a MED |x 071000 |2 bisacsh | |
| 072 | 7 | |a BUS020000 |2 bisacsh | |
| 072 | 7 | |a MED009000 |2 bisacsh | |
| 072 | 7 | |a MED072000 |2 bisacsh | |
| 082 | 0 | 4 | |a 615.1/9 |2 23 |
| 049 | |a UAMI | ||
| 100 | 1 | |a Kinch, Michael, |d 1966- |e author. | |
| 245 | 1 | 2 | |a A prescription for change : |b the looming crisis in drug development / |c Michael S. Kinch. |
| 260 | |a Chapel Hill : |b The University of North Carolina Press, |c 2016. | ||
| 300 | |a 1 online resource (xi, 339 pages) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a data file | ||
| 490 | 1 | |a The Luther H. Hodges Jr. and Luther H. Hodges Sr. series on business, entrepreneurship, and public policy | |
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a Introduction: How Did We Reach This Point? -- Why Regulate Medicines? -- Trials and Tribulations -- Dreams of Greatness: The Birth of the Pharmaceutical Industry -- Triumph and Tragedy -- Ivory Tower of Power -- The DNA of Biotechnology -- Blockbusters and Bombs: Pressures on the Pharmaceutical Industry -- Sea Monsters, Immunauts, and Death Panels -- Drama on the I-270 Tech Corridor -- Autophagy -- Three Views of a Train Wreck -- Bridging the Valley. | |
| 520 | |a The introduction of new medicines has dramatically improved the quantity and quality of individual and public health while contributing trillions of dollars to the global economy. In spite of these past successes -- and indeed because of them -- our ability to deliver new medicines may be quickly coming to an end. Moving from the beginning of the twentieth century to the present, A Prescription for Change reveals how changing business strategies combined with scientific hubris have altered the way new medicines are discovered, with dire implications for both health and the economy. To explain how we have arrived at this pivotal moment, Michael Kinch recounts the history of pharmaceutical and biotechnological advances in the twentieth century. Kinch relates stories of the individuals and organizations that built the modern infrastructure that supports the development of innovative new medicines. He shows that an accelerating cycle of acquisition and downsizing is cannibalizing that infrastructure Kinch demonstrates the dismantling of the pharmaceutical and biotechnological research and development enterprises could also provide opportunities to innovate new models that sustain and expand the introduction of newer and better breakthrough medicines in the years to come. - Publisher. | ||
| 588 | 0 | |a Print version record. | |
| 590 | |a eBooks on EBSCOhost |b EBSCO eBook Subscription Academic Collection - Worldwide | ||
| 650 | 0 | |a Drug development. | |
| 650 | 0 | |a Drugs |x Research |x Economic aspects. | |
| 650 | 0 | |a Pharmaceutical industry. | |
| 650 | 0 | |a Drugs |x Design. | |
| 650 | 2 | |a Drug Design | |
| 650 | 2 | |a Drug Industry | |
| 650 | 6 | |a Médicaments |x Développement. | |
| 650 | 6 | |a Médicaments |x Recherche |x Aspect économique. | |
| 650 | 6 | |a Industrie pharmaceutique. | |
| 650 | 6 | |a Médicaments |x Conception. | |
| 650 | 7 | |a MEDICAL |x Pharmacology. |2 bisacsh | |
| 650 | 7 | |a BUSINESS & ECONOMICS |x Development |x Business Development. |2 bisacsh | |
| 650 | 7 | |a Drugs |x Design |2 fast | |
| 650 | 7 | |a Drug development |2 fast | |
| 650 | 7 | |a Drugs |x Research |x Economic aspects |2 fast | |
| 650 | 7 | |a Pharmaceutical industry |2 fast | |
| 776 | 0 | 8 | |i Print version: |a Kinch, Michael S. |t Prescription for change. |d Chapel Hill : University of North Carolina Press, [2016] |z 9781469630625 |w (DLC) 2016018224 |w (OCoLC)945745514 |
| 830 | 0 | |a Luther H. Hodges, Jr. and Luther H. Hodges, Sr. series on business, entrepreneurship, and public policy. | |
| 856 | 4 | 0 | |u https://ebsco.uam.elogim.com/login.aspx?direct=true&scope=site&db=nlebk&AN=1222280 |z Texto completo |
| 936 | |a BATCHLOAD | ||
| 938 | |a YBP Library Services |b YANK |n 20508348 | ||
| 938 | |a BiblioBoard |b BIBD |n 5a55f71a-3a37-4bd5-9390-6df51fa1ebd6 | ||
| 938 | |a EBL - Ebook Library |b EBLB |n EBL4525807 | ||
| 938 | |a EBSCOhost |b EBSC |n 1222280 | ||
| 938 | |a ProQuest MyiLibrary Digital eBook Collection |b IDEB |n cis35756030 | ||
| 938 | |a Internet Archive |b INAR |n prescriptionforc0000kinc | ||
| 938 | |a Project MUSE |b MUSE |n muse53342 | ||
| 938 | |a YBP Library Services |b YANK |n 12973832 | ||
| 994 | |a 92 |b IZTAP | ||