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EBSCO_ocn959373869 |
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OCoLC |
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20231017213018.0 |
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m o d |
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160926s2016 nyua ob 001 0 eng |
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|a 2016044447
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| 040 |
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|a DLC
|b eng
|e rda
|c DLC
|d OCLCF
|d N$T
|d EBLCP
|d SNK
|d DKU
|d IGB
|d D6H
|d VTS
|d AGLDB
|d G3B
|d S8J
|d S9I
|d IDB
|d STF
|d DLC
|d OCLCO
|d OCLCQ
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| 020 |
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|a 9781536102604
|q ()
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|a 1536102601
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|z 9781536102475
|q (softcover)
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| 035 |
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|a (OCoLC)959373869
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| 042 |
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|a pcc
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1 |
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|a QH671
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| 072 |
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7 |
|a SCI
|x 056000
|2 bisacsh
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|a 571.9/36
|2 23
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| 049 |
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|a UAMI
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| 245 |
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|a Caspases :
|b roles and significance in cell death and disease /
|c Jeffrey Warren, editor.
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| 264 |
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1 |
|a Hauppauge, New York :
|b Nova Science Publisher's, Inc.,
|c [2016]
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| 300 |
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|a 1 online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
0 |
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|a Cell biology research progress
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| 504 |
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|a Includes bibliographical references and index.
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| 588 |
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|a Description based on print version record and CIP data provided by publisher.
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|a Preface; Chapter 1; Caspases: A Driver in Programmed Cell Death; Abstract; 1. Introduction; 2. History of Caspases; 3. Role of Caspases in Apoptosis; 4. Initiator Caspases; 5. Executioner Caspases; 6. Apoptosis Pathways; 6.1. The Extrinsic Route of Apoptosis; 6.1.1. Death Receptor (DR) Pathway of Apoptosis; 6.1.2. Ligand Death Receptor; 6.2. The Intrinsic Route of Apoptosis; 7. Types of Caspase; 7.1. Caspase-1; 7.2. Caspase-2; 7.3. Caspase-3; 7.4. Caspase-6; 7.5. Caspase-7; 7.6. Caspase-8; 7.7. Caspase-9; 7.8. Caspase-10; 7.9. Caspase-12; 7.10. Caspase-14
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| 505 |
8 |
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|a 8. Comparison of Caspase-1, -4, -59. Cellular Proliferation; 9.1. Cellular Differentiation; 9.2. Apoptosis and Immuno-Suppression; 10. General Caspase Inhibition In Vivo; 11. Caspases in Sub-Cellular Compartments; Conclusion and Future Perspectives; References; Chapter 2; Caspases Importance in Cell Death and Disease; Abstract; 1. Introduction; 2. Apoptosis; 3. Necrosis; 4. Caspases Structure; 5. Apoptotic Role; 6. Non Apoptotic Role; 7. Immune Function; 8. An Inflammatory Microenvironment; 9. Mechanisms of Substrate Recognition; 10. Human Caspases; 11. Activity of Caspases in Inflammation
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|a 12. Function of Pattern-Recognition Receptors13. Caspases in Proliferation; 14. Cell Migration; 15. Cell Differentiation; 16. Dimerisation; 17. Cleavage; 18. Caspases in Human Disease; 18.1. Cancer; 18.2. Inflammatory Diseases; 18.3. Gout; 18.4. Cryopyrin-Associated Periodic Syndromes; 18.5. Type 2 Diabetes; 18.6. Familial Mediterranean Fever; 18.7. Pyogenic Sterile Arthritis, Pyoderma Gangrenosum, and Acne Syndrome; 18.8. Hyperimmunoglobulinemia D with Periodic Fever Syndrome; 18.9. Trypanosoma Cruzi Infection; Conclusion and Future Perspectives; References; Chapter 3
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|a The Role of Executioner Caspases in Cancer Formation and MaintenanceAbstract; 1. Introduction; 2. Caspase Family; 2.1. Structural Considerations of Human Executioner Caspases; 2.2. Caspase Substrates; 2.3. Caspase Active Sites; 2.4. Caspase Exosites; 2.5. Caspase Dimerization; 2.6. Executioner Caspase Activation by Proteolysis; 2.7. Caspase Allosteric Sites; 2.8. Post-Translational Modification; 2.8.1. Ubiquitylation; 2.8.2. Phosphorylation; 2.8.3. Nitrosylation; 2.8.4. Acetylation; 2.9. Cellular Localization; 3. Caspase Gene Expression; 3.1. Splice Variants of Executioner Caspases
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| 505 |
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|a 4. Caspase Deficiencies in Cancer4.1. Expression of Caspase Inhibitory Pathways -- Upstream (MOMP) and Downstream (IAPs); 5. Mammalian Models Interrogating Pathophysiological Roles of Executioner Caspases; Conclusion; References; Supplementary Resources; Biographical Sketch; Chapter 4; The Unknown Caspase: The Role of Caspase-14 in Cell Death and Disease; Abstract; Introduction; Caspase-14: Discovery and Structure; The Role of Caspase-14 in Cell Death; The Role of Caspase-14 in Disease; Caspase-14 Protects Against Common Skin Conditions; Caspase-14 Is Implicated in Disorders of the Eye
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| 590 |
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|a eBooks on EBSCOhost
|b EBSCO eBook Subscription Academic Collection - Worldwide
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| 650 |
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0 |
|a Apoptosis.
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| 650 |
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0 |
|a Cell death.
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| 650 |
|
6 |
|a Apoptose.
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| 650 |
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|a Cellules
|x Mort.
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| 650 |
|
7 |
|a SCIENCE / Life Sciences / Anatomy & Physiology
|2 bisacsh
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| 650 |
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7 |
|a Apoptosis.
|2 fast
|0 (OCoLC)fst00811467
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| 650 |
|
7 |
|a Cell death.
|2 fast
|0 (OCoLC)fst00850180
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| 700 |
1 |
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|a Warren, Jeffrey S.,
|e editor.
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| 776 |
0 |
8 |
|i Print version:
|t Caspases
|d Hauppauge, New York : Nova Science Publisher's, Inc., [2016]
|z 9781536102475
|w (DLC) 2016043577
|
| 856 |
4 |
0 |
|u https://ebsco.uam.elogim.com/login.aspx?direct=true&scope=site&db=nlebk&AN=1419139
|z Texto completo
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| 938 |
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|a EBSCOhost
|b EBSC
|n 1419139
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| 938 |
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|a ProQuest Ebook Central
|b EBLB
|n EBL4745823
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| 994 |
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|a 92
|b IZTAP
|
