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EBSCO_ocn958984939 |
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160923s2016 nyu o 000 0 eng d |
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|a 965759738
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|a 9781634852067
|q (electronic bk.)
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|a 1634852060
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|z 9781634851725
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|a 616.831
|2 23
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|a UAMI
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|a Research progress in Alzheimer's disease and dementia.
|n Volume 6 /
|c Miao-Kun Sun, Editor.
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|a New York :
|b Nova Biomedical,
|c [2016]
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|a 1 online resource (viii, 255 pages)
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|a text
|b txt
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|a Print version record.
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|a RESEARCH PROGRESS IN ALZHEIMER'S DISEASE AND DEMENTIA VOLUME 6; RESEARCH PROGRESS IN ALZHEIMER'S DISEASE AND DEMENTIA VOLUME 6; Library of Congress Cataloging-in-Publication Data; CONTENTS; PREFACE; Chapter 1: "LOSS OF THE FUTURE": PROSPECTION IMPAIRMENTS IN THE DEMENTIAS; ABSTRACT; ABBREVIATIONS; 1. INTRODUCTION; 1.1. The Many Functions of Memory Retrieval; 1.2. Episodic Memory as a Constructive Endeavor; 1.3. What Is Prospection?; 1.4. Assessment of Prospection; 2. CHANGES IN PROSPECTION IN HEALTHY AGING; 3. EVIDENCE FOR PERVASIVE FUTURE THINKING DEFICITS IN DEMENTIA
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|a 3.1. Alzheimer's Disease3.1.1. Similarities across Past and Future Contexts in AD; 3.1.2. Neural Correlates of Prospection Deficits in AD; 3.1.3. Scene Construction in AD; 3.2. Amnestic Mild Cognitive Impairment; 3.2.1. Future Directions for Prospection Research In AD and aMCI; 3.3. Semantic Dementia; 3.3.1. Functional Neuroimaging of Future Simulation in SD; 3.3.2. Vulnerability of Contextual Details during Future Simulation in SD; 3.3.3. Reconfiguring of Details during Prospection; 3.4. Behavioral-Variant Frontotemporal Dementia; 3.5. Parkinson's Disease
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|a 3.6. Relationship between Prospection and Functional Impairment in Dementia3.6.1. Prospective Memory in Neurodegenerative Disorders; 3.6.2. Decision-Making Capacity and Prospection in Dementia; 3.6.3. How Loss of the Future Impacts the Self in Dementia; CONCLUSION; ACKNOWLEDGMENTS; REFERENCES; Chapter 2: MEMORY BINDING IN ALZHEIMER'S DISEASE; ABSTRACT; ABBREVIATIONS; 1. INTRODUCTION; 2. THE BINDING PROBLEM; 3. TYPES OF BINDING; 4. MEMORY BINDING IN HEALTHY AGING AND AD; 4.1. Memory Binding in Healthy Aging; 4.2. Memory Binding in AD; 5. MEMORY BINDING IN THE EARLY DIAGNOSIS OF AD
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|a 6. MEMORY BINDING IN THE DIFFERENTIAL DIAGNOSIS OF AD6.1. Studies in Depression; 6.2. Study in Non-AD Dementias; 7. MEMORY BINDING AND THE BRAIN: INSIGHTS INTO THE AD PATHOLOGY; 8. MEMORY BINDING AND PREVENTION INITIATIVES FOR AD; CONCLUSION; ACKNOWLEDGMENTS; REFERENCES; Chapter 3: ALZHEIMER'S DISEASE THERAPY TARGETING BACE1 AND NEPRILYSIN; ABSTRACT; ABBREVIATIONS; 1. INTRODUCTION; 2. APP PROCESSING, Ab PRODUCTION AND Ab DEGRADATION; 3. PRECLINICAL TESTING OF THERAPEUTIC BACE1 INHIBITION; 3.1. Memory Rescue by BACE1 Null Knockout in APP Mice; 3.2. Phenotypes of BACE1 Null Knockout per se
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|a 3.3. BACE1 Haploinsufficiency3.4. Benefits of BACE1 Haploinsufficiency Lessen in APP Mice with Disease Progression; 3.5. BACE1 Inhibitors; 3.6. Strategies to Block BACE1-Elevating Pathways; 3.7. Other Approaches to Inhibit BACE1 Processing of APP; 4. PRECLINICAL TESTING OF THERAPEUTIC NEPRILYSIN ACTIVATION; 4.1. Transgenic Overexpression of Neprilysin; 4.2. Gene Transfer and Pharmacological Strategies to Elevate Neprilysin Expression; 5. PRECLINICAL TESTING OF COMBINATION Ab-LOWERING THERAPIES; CONCLUSION; ACKNOWLEDGMENTS; REFERENCES; Chapter 4: ADVANCES IN TAU IMMUNOTHERAPY; ABSTRACT
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|a eBooks on EBSCOhost
|b EBSCO eBook Subscription Academic Collection - Worldwide
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650 |
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|a Alzheimer's disease.
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|a Alzheimer Disease
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|a Maladie d'Alzheimer.
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|a HEALTH & FITNESS
|x Diseases
|x General.
|2 bisacsh
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|a MEDICAL
|x Clinical Medicine.
|2 bisacsh
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|a MEDICAL
|x Diseases.
|2 bisacsh
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|a MEDICAL
|x Evidence-Based Medicine.
|2 bisacsh
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|a MEDICAL
|x Internal Medicine.
|2 bisacsh
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|a Alzheimer's disease.
|2 fast
|0 (OCoLC)fst00806532
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700 |
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|a Sun, Miao-Kun,
|e editor.
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776 |
0 |
8 |
|i Print version:
|t Research progress in Alzheimer's disease and dementia. Volume 6.
|d New York : Nova Biomedical, [2016]
|z 9781634851725
|w (OCoLC)957521778
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856 |
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|u https://ebsco.uam.elogim.com/login.aspx?direct=true&scope=site&db=nlebk&AN=1356698
|z Texto completo
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938 |
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|a ProQuest Ebook Central
|b EBLB
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