Carnosine : physiological effects and research insights /
Clasificación: | Libro Electrónico |
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Otros Autores: | |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
New York :
Nova Science Publisher's, Inc.,
[2016]
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Colección: | Biochemistry research trends series.
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Temas: | |
Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Preface; Carnosine: Benefits in Meat and; Meat Products Quality and Consumer Health; Abstract; Introduction; Oxidation in Meat and Meat Products; Lipid Oxidation; Protein Oxidation; Factors Influencing Lipid and Protein Oxidation; Antioxidant Strategies against Oxidation of Meat and Meat Products; Mechanisms Mediating the Antioxidant Capacity of Carnosine; Carnosine Content in Meat and Meat Products; Conclusion; References; Biographical Sketches; Perspective Role of Carnosine in Tumor-Related Phenomena; Abstract; 1. Introduction; 1.1. Tumor Microenvironment; 1.1.1. Tumor Hypoxia
- 1.1.2. Hypoxia Induced Carbonic Anhydrase IX1.2. Basic Features of Carnosine; 2. Influence of Carnosine on Tumor Related Acidosis and Its Consequences; 2.1. Suppression of Extracellular Acidosis and Transport Metabolon Formation; 2.2. Effect of Carnosine on Tumor Cells Migration and Invasion; 2.2.1. Interactions between Carnosine and Matrix Metalloproteases; 3. The Impact of Carnosine on Tumor Cell Metabolism; 3.1. Modulation of Cell Hypoxic Response by Carnosine; 3.2. Antioxidative Effect of Carnosine; 3.3. Glycolysis Pathway as a Target of Carnosine Action
- 3.3.1. Glycolytic Enzymes Regulated by Hypoxia3.3.2. Possible Mechanisms of Carnosine Control of Glycolysis; 3.4. Carnosine and Mitochondrial Respiration; 4. Different Ways of the Carnosine Influence on Tumor Cell Proliferation; 4.1. Carnosine and Cell Cycle Regulation; 4.2. Carnosine as a Mimic of Rapamycin in mTOR Signaling Pathway; 5. Possible Use of Carnosine during Anticancer Therapy; 5.1. Platinum Based Drugs and Carnosine; 5.2. Intercalating Chemotherapeutics and Carnosine; 5.3. Protective Effects of Carnosine during Chemotherapy and Radiotherapy; Conclusion; Acknowledgments
- Carnosine: A Regulator of Metal Homeostasis in the SynapseConclusion; References; Neurotropic and Protective Effects of L-carnosine: Studies In Vitro; Abstract; Introduction; Material and Methods; Results; Neurotropic Effects of L-Carnosine; Effects L-Carnosine on Plasticity in Olfactory Cortex Slices; The Protective Effect of L-Carnosine in the Model of Hemorrhagic Stroke in Vitro; The Protective Effect of L-Carnosine on the Activity of Ionotropic Glutamatergic Receptor Mechanisms after Freezing/Rewarming of Brain Slices