Snake venoms and envenomation : modern trends and future prospects /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Utkin, Yuri N. (Editor ), Krivoshein, Arcadius V. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Hauppauge, New York : Nova Science Publisher's, Inc., [2016]
Colección:Medicine and biology research developments
Temas:
Poisonous snakes > Venom.
Toxins.
Antivenins.
Snake Venoms > pharmacology
Snake Bites > pathology
Antivenins
Snake Venoms
Toxins, Biological
Serpents venimeux > Venin.
Toxines.
Sérum antivenimeux.
TRAVEL > Asia > General.
Poisonous snakes > Venom
Toxins
Acceso en línea:Texto completo
Tabla de Contenidos:
  • SNAKE VENOMS AND ENVENOMATION MODERN TRENDS AND FUTURE PROSPECTS; SNAKE VENOMS AND ENVENOMATION MODERN TRENDS AND FUTURE PROSPECTS; Library of Congress Cataloging-in-Publication Data; CONTENTS; PREFACE; SECTION ONE: GENERAL ASPECTS; Chapter 1: SNAKES: DIVERSITY, EPIDEMIOLOGY AND ENVENOMATION; ABSTRACT; GENERAL ASPECTS; EPIDEMIOLOGY AND ENVENOMATION; South Asia; Africa; Europe; Americas; Australia; CONCLUSION; REFERENCES; Chapter 2: VENOMS FROM "NON-VENOMOUS" SNAKES: REAR-FANGED SNAKE VENOMS AS SOURCES OF NOVEL COMPOUNDS; ABSTRACT; INTRODUCTION
  • BIOLOGY OF REAR-FANGED SNAKES: ITS RELEVANCE TO TOXINOLOGISTSDiversity; Gland Structure
  • The Duvernoy's Venom Gland; Venom Yields; COMPOSITION OF VENOM FROM REAR-FANGED SNAKES; Analysis of Venoms; Mass Spectrometry, Proteomic Analysis and Transcriptomic Analyses ofRear-Fanged Snake Venoms; Enzymes; PIII Metalloprotease; Matrix Metalloproteinase; Serine Proteinase; Acetylcholinesterase (AChE); Phospholipase A2; Non-Enzymatic Toxins; Cysteine-Rich Secretory Proteins (CRiSPs); Three-Finger Toxins; Other Components; DRUG DEVELOPMENT POTENTIAL; CONCLUSION AND FUTURE DIRECTIONS; REFERENCES
  • Chapter 3: VENOM PRODUCTION IN THE 21ST CENTURYABSTRACT; INTRODUCTION; LEGAL CONSIDERATIONS; SAFETY; HUSBANDRY; Biology of the Animals; New Specimens; Feeding; Disease Control; Cleaning/Disinfecting; Record Keeping; Breeding; EXTRACTIONS; REFERENCES; SECTION TWO: CLINICAL AND PATHOPHYSIOLOGICAL ASPECTS; Chapter 4: EXTENDING THE USE OF SNAKE VENOMS TO THERAPEUTICS; ABSTRACT; INTRODUCTION; HISTORICAL USE; DRUG QUALITY; DRUG ENGINEERING; ROUTE OF ADMINISTRATION OPTIONS; PRODUCT PROTECTION STRATEGIES; Patent Term Extensions; Orphan Drug Status
  • New Chemical/Molecular Entities (NCE/NME) Market ExclusivityBiologic Exclusivity; PRECLINICAL ANIMAL STUDIES; REGULATORY STRATEGY; CLINICAL TRIALS; CONCLUSION; REFERENCES; Chapter 5: PATHOPHYSIOLOGICAL SIGNIFICANCE AND THERAPEUTIC IMPLICATIONS OF RUSSELL'S VIPER VENOM PROTEINS AND PEPTIDES AFFECTING BLOOD COAGULATION; ABSTRACT; INTRODUCTION; HEMOSTATICALLY ACTIVE PROTEINS AND PEPTIDES FROM RVV; Procoagulant Proteins Isolated from RVV: Structure-Functional Propertiesand Mechanisms of Action; Factor X Activators; Factor V Activators; Thrombin-Like Enzymes; Prothrombin Activators
  • Anticoagulant Proteins from RVV: Structure-Functional Properties andMechanisms of ActionAnticoagulant Proteins Possessing Enzymatic Activity; Phospholipase A2 (PLA2) Enzymes; Fibrino(geno)lytic Proteases; Non-Enzymatic Anticoagulant Proteins/Peptides; Kunitz-Type Serine Protease Inhibitors; C-Type Lectin Like Proteins; An Apoptosis-Inducing Anticoagulant Peptide; Pharmacological Properties and Toxicity of Procoagulant and Anticoagulant Proteins/Peptides Purified from RVV; Biomedical Applications of RVV Proteins/Peptides Affecting Hemostasis; CONCLUSION; ACKNOWLEDGMENTS; REFERENCES

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