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EBSCO_ocn949912272 |
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160516s2016 nyu ob 001 0 eng |
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|a 957739686
|a 958083885
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|a 9781634847742
|q (ebook)
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|a 1634847741
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|z 9781634847438
|q (hardcover)
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|z (OCoLC)957739686
|z (OCoLC)958083885
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|a 915.9/42
|2 23
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| 049 |
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|a UAMI
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| 245 |
0 |
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|a Snake venoms and envenomation :
|b modern trends and future prospects /
|c editors, Yuri N. Utkin, and Arcadius V. Krivoshein (Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia, and others).
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| 264 |
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1 |
|a Hauppauge, New York :
|b Nova Science Publisher's, Inc.,
|c [2016]
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| 300 |
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|a 1 online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 347 |
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|a data file
|2 rda
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| 490 |
0 |
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|a Medicine and biology research developments
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| 504 |
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|a Includes bibliographical references and index.
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| 588 |
0 |
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|a Print version record and CIP data provided by publisher.
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| 505 |
0 |
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|a SNAKE VENOMS AND ENVENOMATION MODERN TRENDS AND FUTURE PROSPECTS; SNAKE VENOMS AND ENVENOMATION MODERN TRENDS AND FUTURE PROSPECTS; Library of Congress Cataloging-in-Publication Data; CONTENTS; PREFACE; SECTION ONE: GENERAL ASPECTS; Chapter 1: SNAKES: DIVERSITY, EPIDEMIOLOGY AND ENVENOMATION; ABSTRACT; GENERAL ASPECTS; EPIDEMIOLOGY AND ENVENOMATION; South Asia; Africa; Europe; Americas; Australia; CONCLUSION; REFERENCES; Chapter 2: VENOMS FROM "NON-VENOMOUS" SNAKES: REAR-FANGED SNAKE VENOMS AS SOURCES OF NOVEL COMPOUNDS; ABSTRACT; INTRODUCTION
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| 505 |
8 |
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|a BIOLOGY OF REAR-FANGED SNAKES: ITS RELEVANCE TO TOXINOLOGISTSDiversity; Gland Structure -- The Duvernoy's Venom Gland; Venom Yields; COMPOSITION OF VENOM FROM REAR-FANGED SNAKES; Analysis of Venoms; Mass Spectrometry, Proteomic Analysis and Transcriptomic Analyses ofRear-Fanged Snake Venoms; Enzymes; PIII Metalloprotease; Matrix Metalloproteinase; Serine Proteinase; Acetylcholinesterase (AChE); Phospholipase A2; Non-Enzymatic Toxins; Cysteine-Rich Secretory Proteins (CRiSPs); Three-Finger Toxins; Other Components; DRUG DEVELOPMENT POTENTIAL; CONCLUSION AND FUTURE DIRECTIONS; REFERENCES
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| 505 |
8 |
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|a Chapter 3: VENOM PRODUCTION IN THE 21ST CENTURYABSTRACT; INTRODUCTION; LEGAL CONSIDERATIONS; SAFETY; HUSBANDRY; Biology of the Animals; New Specimens; Feeding; Disease Control; Cleaning/Disinfecting; Record Keeping; Breeding; EXTRACTIONS; REFERENCES; SECTION TWO: CLINICAL AND PATHOPHYSIOLOGICAL ASPECTS; Chapter 4: EXTENDING THE USE OF SNAKE VENOMS TO THERAPEUTICS; ABSTRACT; INTRODUCTION; HISTORICAL USE; DRUG QUALITY; DRUG ENGINEERING; ROUTE OF ADMINISTRATION OPTIONS; PRODUCT PROTECTION STRATEGIES; Patent Term Extensions; Orphan Drug Status
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| 505 |
8 |
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|a New Chemical/Molecular Entities (NCE/NME) Market ExclusivityBiologic Exclusivity; PRECLINICAL ANIMAL STUDIES; REGULATORY STRATEGY; CLINICAL TRIALS; CONCLUSION; REFERENCES; Chapter 5: PATHOPHYSIOLOGICAL SIGNIFICANCE AND THERAPEUTIC IMPLICATIONS OF RUSSELL'S VIPER VENOM PROTEINS AND PEPTIDES AFFECTING BLOOD COAGULATION; ABSTRACT; INTRODUCTION; HEMOSTATICALLY ACTIVE PROTEINS AND PEPTIDES FROM RVV; Procoagulant Proteins Isolated from RVV: Structure-Functional Propertiesand Mechanisms of Action; Factor X Activators; Factor V Activators; Thrombin-Like Enzymes; Prothrombin Activators
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| 505 |
8 |
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|a Anticoagulant Proteins from RVV: Structure-Functional Properties andMechanisms of ActionAnticoagulant Proteins Possessing Enzymatic Activity; Phospholipase A2 (PLA2) Enzymes; Fibrino(geno)lytic Proteases; Non-Enzymatic Anticoagulant Proteins/Peptides; Kunitz-Type Serine Protease Inhibitors; C-Type Lectin Like Proteins; An Apoptosis-Inducing Anticoagulant Peptide; Pharmacological Properties and Toxicity of Procoagulant and Anticoagulant Proteins/Peptides Purified from RVV; Biomedical Applications of RVV Proteins/Peptides Affecting Hemostasis; CONCLUSION; ACKNOWLEDGMENTS; REFERENCES
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| 590 |
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|a eBooks on EBSCOhost
|b EBSCO eBook Subscription Academic Collection - Worldwide
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| 650 |
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0 |
|a Poisonous snakes
|x Venom.
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| 650 |
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0 |
|a Toxins.
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| 650 |
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0 |
|a Antivenins.
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| 650 |
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2 |
|a Snake Venoms
|x pharmacology
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| 650 |
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2 |
|a Snake Bites
|x pathology
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| 650 |
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2 |
|a Antivenins
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| 650 |
|
2 |
|a Snake Venoms
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| 650 |
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2 |
|a Toxins, Biological
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| 650 |
|
6 |
|a Serpents venimeux
|x Venin.
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| 650 |
|
6 |
|a Toxines.
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| 650 |
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6 |
|a Sérum antivenimeux.
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| 650 |
|
7 |
|a TRAVEL
|z Asia
|x General.
|2 bisacsh
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| 650 |
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7 |
|a Antivenins
|2 fast
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| 650 |
|
7 |
|a Poisonous snakes
|x Venom
|2 fast
|
| 650 |
|
7 |
|a Toxins
|2 fast
|
| 700 |
1 |
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|a Utkin, Yuri N.,
|e editor.
|
| 700 |
1 |
|
|a Krivoshein, Arcadius V.,
|e editor.
|
| 776 |
0 |
8 |
|i Print version:
|t Snake venoms and envenomation.
|d Hauppauge, New York : Nova Science Publisher's, Inc., [2016]
|z 9781634847438
|w (DLC) 2016004805
|
| 856 |
4 |
0 |
|u https://ebsco.uam.elogim.com/login.aspx?direct=true&scope=site&db=nlebk&AN=1258662
|z Texto completo
|
| 938 |
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|a EBSCOhost
|b EBSC
|n 1258662
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| 938 |
|
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|a YBP Library Services
|b YANK
|n 12882113
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| 994 |
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|a 92
|b IZTAP
|
