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160108s2016 nyu o 001 0 eng |
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|a 960444054
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|a 572.8/65
|2 23
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| 049 |
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|a UAMI
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| 245 |
0 |
0 |
|a Epigenetics :
|b mechanisms and clinical perspectives /
|c Yildiz Dincer, editor.
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| 264 |
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1 |
|a New York :
|b Nova Biomedical,
|c [2016]
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| 300 |
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|a 1 online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 347 |
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|a data file
|2 rda
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| 490 |
1 |
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|a Genetics - research and issues
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| 500 |
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|a Includes index.
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| 588 |
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|a Description based on print version record and CIP data provided by publisher.
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| 504 |
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|a Includes bibliographical references and index.
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0 |
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|a EPIGENETICS MECHANISMS AND CLINICAL PERSPECTIVES; EPIGENETICS MECHANISMS AND CLINICAL PERSPECTIVES; CONTENTS; PREFACE ; Chapter 1 EPIGENETIC MODIFICATIONS AND DEVELOPMENTAL ORIGIN OF HEALTH AND DISEASES (DOHAD) ; Abstract; Abbreviations; 1. Introduction; 2. What Is Epigenetics?; 2.1. DNA Methylation; 2.2. MicroRNAs; 3. Evidence from Human Cohorts; 3.1. Fetal Programming Hypothesis; 3.2. DNA Methylation and Fetal Programming Hypothesis; 3.3. MicroRNAs and Fetal Programming Hypothesis; 4. Evidence from Animal Experiments; 4.1. DNA Methylation and Animal Experiments
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| 505 |
8 |
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|a 4.1.1. Maternal Nutrition4.1.2. Paternal Nutrition; 4.2. MicroRNAs and Animal Experiments; 4.2.1. Maternal Nutrition; 4.2.2. Paternal Nutrition; 5. Developmental Plasticity and Reversibility; Conclusion and Further Perspective; References; Chapter 2 EFFECTS OF OXIDATIVE STRESS ON EPIGENETIC MECHANISMS ; Abstract; Abbreviations; 1. Epigenetic Mechanisms; 1.1. DNA Methylation; 1.2. Histone Post-translational Modifications; 1.3. Micro RNAs and Epigenetic; 2. Oxidative Stress; 3. Interactions between Oxidative Stress and Epigenetic Mechanisms; 3.1. Oxidative Stress -- DNA Methylation
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| 505 |
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|a 3.2. Oxidative Stress -- Histone Post-Translational Modifications3.3. Oxidative Stress -- miRNAs; Conclusion; References; Chapter 3 EPIGENETIC MODIFICATIONS AND THEIR POTENTIAL ROLE IN TUMORIGENESIS ; Abstract; Abbreviations; 1. Introduction; 2. The Dysregulation of Epigenetic Factors in Various Cancers; 2.1. The Deregulation of DNA Methylation in Cancer; 2.2. The Deregulation of Histone Lysine Methylation in Cancer; 2.3. The Deregulation of Histone Lysine Demethylases in Cancer; 3. Histone Lysine Acetylation in Cancer
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| 505 |
8 |
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|a 3.1. The Deregulation of Histone Lysine Acetyltransferases in Tumor Proliferation and Metastasis3.2. The Deregulation of Histone Lysine Deacetylases (KDACs) in Cancer; 4. Histone Acetylation "Code" as a Diagnostic Marker for Cancer Progression; 5. Epigenetic Modifications in Oncogenes and Tumor Suppressor Genes; 6. Epigenetic Modifications in Cellular Signaling Pathways; 6.1. NF-(B Signaling Pathway; 6.2. STAT3 Signaling Cascade; 6.3. Wnt/(-Catenin Signaling Pathway; 7. Epigenetic Modification in Cancer Stem Cells
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| 546 |
|
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|a English.
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| 590 |
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|a eBooks on EBSCOhost
|b EBSCO eBook Subscription Academic Collection - Worldwide
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| 650 |
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0 |
|a Epigenetics.
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| 650 |
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0 |
|a Genetic regulation.
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| 650 |
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2 |
|a Epigenomics
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| 650 |
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2 |
|a Gene Expression Regulation
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| 650 |
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6 |
|a Épigénétique.
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| 650 |
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6 |
|a Régulation génétique.
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| 650 |
|
7 |
|a SCIENCE
|x Life Sciences
|x Biochemistry.
|2 bisacsh
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| 650 |
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7 |
|a Epigenetics.
|2 fast
|0 (OCoLC)fst01893642
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| 650 |
|
7 |
|a Genetic regulation.
|2 fast
|0 (OCoLC)fst00940086
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| 700 |
1 |
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|a Dincer, Yildiz,
|e editor.
|
| 776 |
0 |
8 |
|i Print version:
|t Epigenetics
|d Hauppauge, New York : Nova Science Publisher's, Inc., [2016]
|z 9781634844901
|w (DLC) 2015050167
|
| 830 |
|
0 |
|a Genetics--research and issues series.
|
| 856 |
4 |
0 |
|u https://ebsco.uam.elogim.com/login.aspx?direct=true&scope=site&db=nlebk&AN=1226247
|z Texto completo
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|b EBLB
|n EBL4586617
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|b IZTAP
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