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EBSCO_ocn921216860 |
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OCoLC |
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20231017213018.0 |
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m o d |
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150914s2015 enk ob 001 0 eng d |
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|a 920820521
|a 945873236
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|a 1910242128
|q (electronic bk.)
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|a 9781910242124
|q (electronic bk.)
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|a 9781680158939
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|z 191024211X
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|b BV044060035
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|a DEBSZ
|b 493168176
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|a (OCoLC)921216860
|z (OCoLC)920820521
|z (OCoLC)945873236
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|a 828635
|b MIL
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4 |
|a RS192
|b .P73 2015eb
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|a MED
|x 071000
|2 bisacsh
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| 082 |
0 |
4 |
|a 615.19
|2 23
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| 049 |
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|a UAMI
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| 245 |
0 |
0 |
|a Practical guide to hot-melt extrusion :
|b continuous manufacturing and scale-up.
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| 260 |
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|a London :
|b Smithers Rapra,
|c 2015.
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| 300 |
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|a 1 online resource
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 504 |
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|a Includes bibliographical references and index.
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| 505 |
0 |
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|a Preface; Contents; Contributors; 1 Introduction to Hot-Melt Extrusion, Continuous Manufacturing: Scale-up via Hot-Melt Extrusion; 1 Background; 1.1 Introduction; 1.1.1 Hot-Melt Extrusion Process Technology; 1.1.2 Equipment; 1.1.3 Benefits and Drawbacks to Hot-Melt Extrusion; 1.1.4 Application of Hot-Melt Extrusion; 1.1.5 Materials used in Hot-Melt Extrusion Processes; 1.1.6 Development of Sustained-release Formulations; 1.1.7 Marketed Products; 1.2 Continuous Manufacturing; 1.3 Scale-up via Hot-Melt Process; 1.3.1 Case Study: Scale-up of a Hot-Melt Extrusion Process using Soluplus as Carrier.
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|a 1.4 ConclusionsReferences; 2 Hot-Melt Extrusion as Continuous Manufacturing Technique, Current Trends and Future Perspectives; 2.1 Hot-Melt Extrusion as Continuous Manufacturing Technique; 2.1.1 Hot-Melt Extrusion Equipment; 2.1.2 Single-screw Extruder; 2.1.3 Twin-screw Extruders; 2.1.4 Role of Glass Transition Temperature; 2.1.5 Role of Mechanical Parameters; 2.1.6 Use of Plasticisers or Surfactants; 2.1.7 Challenges and Opportunities; 2.2 Background Information on Batch Processing; 2.2.1 Past and Future Trends of Continuous Manufacturing; 2.2.2 Conventional Batch Process Design.
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|a 2.2.3 Production Parameters2.2.4 Production Parameters in Batch Processing; 2.2.4.1 Active Pharmaceutical Ingredient(s) Manufacturing Site; 2.2.4.2 Formulation Development; 2.2.4.3 Industrial Scale-up; 2.2.4.4 Regulatory Guidelines; 2.2.5 Validation of Batch Processing; 2.2.6 In-line Continuous Monitoring Techniques; 2.3 Assimilation of Complete Quality-by-Design Models; 2.3.1 Chief Modification in Procedural Expertise for Continuous Manufacturing; 2.3.2 Process Parameters for Preformulation for Hot-Melt Extrusion; 2.3.3 Implementation of a New Product Development Process.
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| 505 |
8 |
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|a 2.3.3.1 Modelling Simulation of Hot-Melt Extrusion Process2.3.4 Flow Chart Model for Continuous Hot-Melt Extrusion based Pharmaceutical Manufacturing Process; 2.3.5 Foremost Alteration in Structural Provisions for Quality and Technical Operations; 2.3.6 Potential Benefits of Continuous Hot-Melt Extrusion Manufacturing; 2.3.7 Regulatory Issues Related to Hot-Melt Extrusion; 2.3.8 Process Analytical Technology Framework; 2.4 Conclusion; References; 3 Co-extrusion as a Novel Approach in Continuous Manufacturing Compliance; 3 Background; 3.1 Introduction.
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| 505 |
8 |
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|a 3.2 Applications of Co-extrusion via Hot-Melt Extrusion in Continuous Manufacturing3.2.1 Problem Encountered During Co-extrusion; 3.2.2 Variation of the Die Temperature; 3.2.3 Swelling of the Die; 3.2.4 Viscosity Matching; 3.2.5 Adhesion; 3.2.6 Interdiffusion; 3.2.7 Delamination; 3.3 Pharmaceutical Applications; 3.3.1 Pharmaceutical Significance of the Co-extrusion Technique; 3.4 Case Study; 3.5 Conclusions; References; 4 Solid-state Engineering of Drugs using Melt Extrusion in Continuous Process; 4 Introduction; 4.1 Dissolution Enhancement; 4.1.1 Use of Novel Inorganic Excipients.
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| 590 |
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|a eBooks on EBSCOhost
|b EBSCO eBook Subscription Academic Collection - Worldwide
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| 650 |
|
0 |
|a Pharmaceutical technology.
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| 650 |
|
0 |
|a Drugs
|x Extrusion.
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| 650 |
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2 |
|a Technology, Pharmaceutical
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| 650 |
|
6 |
|a Techniques pharmaceutiques.
|
| 650 |
|
6 |
|a Médicaments
|x Extrusion.
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| 650 |
|
7 |
|a MEDICAL
|x Pharmacology.
|2 bisacsh
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| 650 |
|
7 |
|a Pharmaceutical technology
|2 fast
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| 700 |
1 |
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|a Maniruzzaman, Mohammed,
|e editor.
|
| 776 |
0 |
8 |
|i Print version:
|z 9781910242124
|
| 856 |
4 |
0 |
|u https://ebsco.uam.elogim.com/login.aspx?direct=true&scope=site&db=nlebk&AN=1061142
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|a Askews and Holts Library Services
|b ASKH
|n AH33814633
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|a ProQuest Ebook Central
|b EBLB
|n EBL4394769
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| 938 |
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|a EBSCOhost
|b EBSC
|n 1061142
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|a ProQuest MyiLibrary Digital eBook Collection
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