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|a Whalley, Lawrence J.,
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|a Understanding brain aging and dementia :
|b a life course approach /
|c Lawrence J. Whalley.
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|a New York, NY :
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|a 1 online resource (xxxiv, 403 pages) :
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|a Includes bibliographical references and index.
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|a Introduction -- The life course approach -- The well-connected brain -- Evolution, aging, and dementia -- The aging brain -- The biology of the dementias -- The disconnected mind -- Emotional aging -- Dementia syndromes -- Dementia risk reduction, 1: concepts, reserve and early life opportunities -- Dementia risk reduction, 2: midlife opportunities to delay dementia onset -- Dementia risk reduction, 3: multidomain approaches.
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|a The life course method compares an individual's long-life and late-life behaviors to gauge one's mental decay. Arguing the life course approach is the best and simplest model for tracking mental development, Lawrence J. Whalley unlocks the mysteries of brain functionality, illuminating the processes that affect the brain during aging, the causes behind these changes, and effective coping strategies. Whalley identifies the genetic factors that determine the pace of aging and the behaviors, starting in childhood, that influence how we age. Through vignettes, charts, and tables, he composes an ac.
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|a Dementia
|x Diagnosis.
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|a Dementia
|x Treatment.
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|a Aging.
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1 |
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|a Aging
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|a Brain
|x growth & development
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1 |
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|a Dementia
|x prevention & control
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|a Démence
|x Traitement.
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|a Vieillissement.
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|a HEALTH & FITNESS
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|x Alzheimer's & Dementia.
|2 bisacsh
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|a Aging
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|a Dementia
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|a Dementia
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|i Print version:
|a Whalley, Lawrence J.
|t Understanding brain aging and dementia.
|d New York : Columbia University Press, [2015]
|z 9780231163828
|w (DLC) 2014036252
|w (OCoLC)890851066
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|6 505-00/(S
|a Introduction -- Life Histories and the Life Course Approach -- Greater Numbers of the Elderly -- The Role of Epigenetics in Brain Aging and Dementia -- Social Class and the Life Course -- The Study of Individual Differences -- Resilience and Social Capital -- Developmental Origins of Adult Disease -- Limitations of Association Studies and the Perils of Reductionism -- Systems Biology, Reductionism, and the Value of Visualization -- The Biology of the Aging Mind and Brain -- Social Cognition, Aging, and Dementia -- The Life Course Approach -- Influential Ideas -- Developmental Stages -- Critical Periods -- Programmed Development and Aging -- Three Lives -- The Developmental Origins of Aging and Adult Disease -- Bringing It All Together -- The Well-Connected Brain -- A Brief Introduction to the Nervous System -- Functional Organization -- Diffusion Tensor Imaging -- Brain Structures and Functions Relevant to Aging -- Blueprints for a Well-Connected Brain -- The Brain and Language -- Brain Maps -- Bringing It All Together -- Evolution, Aging, and Dementia -- Introduction -- Is AD Specific to Humans-- Human Evolution -- Are the Most Evolved Neural Networks More Vulnerable to AD-- Is Reactivation of Developmental Programs in the Course of AD Incompatible with the Mature Brain-- Brain Aging and the Evolution of Neurological Disease -- Bringing It All Together -- The Aging Brain -- Introduction -- The Frontal Lobes and Aging -- Brain Blood Vessels -- Genes, Diet, and Behavior -- Stress Responses and the Aging Brain -- Bringing It All Together -- The Biology of the Dementias -- Historical Trends -- The Modern Era: Focus on β-Amyloid -- Molecular Biology of Tau -- Vascular Cognitive Impairment and Dementia -- The Modern Era: Focus on the Biology of Aging -- Breakdown of Neural Networks in Dementia -- Bringing It All Together -- The Disconnected Mind -- Introduction -- Cognitive Aging -- Sensory Systems -- What Influences Rates of Cognitive Aging-- Attention -- Information Processing -- General Mental Ability -- Memory -- Vulnerable People -- Personality and Cognitive Aging -- Bringing It All Together -- Emotional Aging -- Emotional Life -- Older Adults as Emotional Experts -- Emotional States -- The Aging Brain and Emotional Aging -- The Anatomy of Emotion -- Emotional Intelligence -- Older Adults as Actors -- Life Narratives, Self-concept, and Possible Selves in Late Life -- Social Support, Social Cohesion, and Social Pain -- How Much Time Is Left-- Bringing It All Together -- Dementia Syndromes -- Introduction -- Alzheimer's Disease -- Brain Imaging in Early Dementia -- Frontotemporal Dementias -- Parkinsons Disease with Dementia -- Dementias Associated with Brain Blood Vessel Disease -- Bringing It All Together -- Dementia Risk Reduction, 1: Concepts, Reserve, and Early Life Opportunities -- The Dementia Epidemic -- Cognitive Reserve -- Biological Plausibility of Strategies to Reduce the Risk of Dementia -- Early Life Opportunities to Prevent Dementia -- Bringing It All Together -- Dementia Risk Reduction, 2: Midlife Opportunities to Delay Dementia Onset -- The Neurovascular Hypothesis -- The Inflammatory and Metabolic Hypotheses -- The Amyloid and Related Therapeutic Approaches Hypothesis -- Stress, Depression, and the Role of Growth Factors -- The Brain Activity Hypothesis -- Bringing It All Together -- Dementia Risk Reduction, 3: Multidomain Approaches -- Background -- Nutrients and Dementia -- The Multidomain Hypothesis -- Bringing It All Together.
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