Engineering of chemical complexity /
This second review volume is a follow-up to the book "Engineering of Chemical Complexity" that appeared in 2013. Co-edited by the Nobel laureate Gerhard Ertl, this book provides a broad perspective over the current research aimed at understanding, the design and control of complex chemical...
Clasificación: | Libro Electrónico |
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Otros Autores: | , |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
New Jersey :
World Scientific,
[2013]
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Colección: | World Scientific lecture notes in complex systems ;
v. 11. |
Temas: | |
Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Preface; CONTENTS; 1. From Simple to Complex Oscillatory Behavior in Cellular Regulatory Networks; 1. Introduction; 2. From Simple to Complex Oscillatory Dynamics in a Prototype Biochemical Model; 3. Simple Periodic Behavior in the Cdk Regulatory Network Driving the Mammalian Cell Cycle; 4. Complex Oscillatory Behavior in the Cdk Network; 5. Comparison with Other Oscillatory Cellular Networks; Acknowledgments; References; 2. Time Dependent Michaelis-Menten Equations for Open Enzyme Networks; 1. Introduction; 2. The Michaelis-Menten Equation.
- 3. Perturbation Analysis of the Michaelis-Menten Equations4. Basic Open-Enzyme Network; 4.1. Perturbation analysis; 4.2. Time-dependent Michaelis-Menten equations for a larger network; 4.3. Accuracy of the perturbation scheme; 4.4. Simulation results and discussion; 5. Conclusion; Acknowledgments; References; 3. Environmental Dependence of the Activity and Essentiality of Reactions in the Metabolism of Escherichia Coli; 1. Introduction; 1.1. Structure: Metabolism as a complex network; 1.2. Function: Flux Balance Analysis; 1.3. Previous work on activity and essentiality of reactions in silico.
- 2. Methods2.1. Genome-scale representation of metabolism; 2.2. Media composition; 2.3. FBA implementation; 2.4. Quantitative definition of activity and essentiality; 3. Results and Discussion; 3.1. Essential whenever active reactions; 3.2. Always active reactions; 3.3. Never essential reactions; 3.4. Partially essential reactions; 4. Conclusions; Acknowledgments; References; 4. Chemically-Driven Biological Brownian Machine; 1. Introduction; 2. Dynamics of Single Myosin Motor Proteins; 3. Mechano-Chemical Coupling of Myosin-V and -VI; 4. Strain-Sensor Mechanism.
- 4.1. Quantification of mechano-sensitivity for the weak-to-strong transition4.2. Strain sensor as a rectifier of Brownian motion; 4.3. Inhibition of ATP synthesis; 5. Energetics of Myosin Motor; 5.1. Single molecule force measurement using DNA handle; 5.2. Fluctuation between lever-arm swing and the reversal under load; 5.3. Lever-arm swing versus Brownian search-and-catch; 6. Physiological Advantages of the Brownian Machine; Acknowledgments; References; 5. Diffusiophoretic Nano and Microscale Propulsion and Communication; 1. Introduction; 1.1. Reynold's number and Brownian motion.
- 2. Mechanisms of Motility2.1. Electrolyte diffusiophoresis; 3. Diffusiophoresis-Based Systems; 3.1. Externally triggered diffusiophoretic systems; 3.1.1. "On/off" micro-pump and photo-colloidal diode; 3.1.2. Triggered crack-detection, targeting and repair using ion gradients; 3.2. Self-triggered diffusiophoretic system: Collective behaviors of micromotors in response to orthogonal stimuli; 3.2.1. Reversible transition between "exclusion" and "schooling"; 3.2.2. "Exclusion" in response to UV light; 3.2.3. Design of logic gate based on orthogonal stimuli; 4. Conclusion; References.