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The antibody molecule : from antitoxins to therapeutic antibodies /
'The Antibody Molecule' follows the extraordinary journey of the medics and scientists who shaped the course of medical advances in the field of immunology which has seen chemists, physicists and biologists alike seeking to unravel the most complex system in the human body outside the brai...
| Clasificación: | Libro Electrónico |
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| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Oxford :
Oxford University Press,
2015.
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| Edición: | First edition. |
| Colección: | Oxford medical histories.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Cover; The Antibody Molecule; Copyright; Dedication; Contents; Abbreviations; 1 Antibody pre-history: The emergence of empirical immunology; 2 Pre-molecular immunology: The dawn of mechanism; 3 Structural chemistry: Locks, keys, and colloids; 4 The foundations of antibody-antigen recognition emerge; 5 The cellular reformation; 6 The molecular path unfolds; 7 Uncovering the origins of antibody diversity; 8 Immunoglobulin constant regions; 9 Effector functions of constant regions; 10 Transmission and catabolism of IgG; 11 The structural context of antibody diversity
- 12 Monoclonal antibodies and the mechanisms of hypermutation13 Antibody structure prediction and development of humanization strategies ; 14 Antibody engineering: Improving on natural immunity; 15 Therapeutic antibodies: Case study I: Prevention of respiratory syncytial virus illness; 16 Therapeutic antibodies: Case study II: Targeting breast cancer; 17 Antibodies: The therapeutic future; Author Index; Subject Index