Advanced topics in forensic DNA typing : interpretation /

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The first edition of Forensic DNA Typing, published in 2001, by John Butler quickly established itself as the gold-standard reference for the field. Over the next ten years, the vast amount of new information uncovered has resulted in this new volume, Advanced Topics in Forensic DNA Typing: Interpre...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Butler, John M. (John Marshall), 1969-
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Oxford, England ; San Diego, California : Academic Press, 2015.
Temas:
DNA fingerprinting > Moral and ethical aspects.
DNA fingerprinting > Congresses.
DNA Fingerprinting > methods
Empreintes génétiques > Aspect moral.
Empreintes génétiques > Congrès.
MEDICAL > Forensic Medicine.
MEDICAL > Preventive Medicine.
MEDICAL > Public Health.
DNA fingerprinting
Conference papers and proceedings
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; Contributors; ADVANCED TOPICS IN FORENSIC DNA TYPING: INTERPRETATION; Copyright; Dedication; Contents; Foreword; Introduction; NEW MATERIAL IN THIS VOLUME; OVERVIEW OF BOOK CHAPTERS; References; Acknowledgments; Reference; About the Author; Reference; SECTION I -DATA INTERPRETATION; Chapter 1
  • Data Interpretation Overview; PURPOSE OF THIS BOOK; THE INTERPRETATION PROCESS; CHARACTERISTICS OF IDEAL DATA; GUIDANCE FOR DNA INTERPRETATION; A MATCH OR NOT A MATCH: THAT IS THE QUESTION ... ; STR LOCI, KITS, AND POPULATION DATA; SUMMARY; Reading List and Internet Resources.
  • Chapter 2
  • Data, Models, ThresholdsDATA COLLECTION IN ABI GENETIC ANALYZERS11CERTAIN COMMERCIAL EQUIPMENT, INSTRUMENTS, AND MATERIALS ARE IDENTIFIED IN ORDER ... ; MODELS; THRESHOLDS USED IN STR TYPING; SETTING AND USING ANALYTICAL THRESHOLDS; Reading List and Internet Resources; Chapter 3
  • STR Alleles and Amplification Artifacts; INTRODUCTION; OVERVIEW OF THE STR TYPING PROCESS; STR ALLELES AND THEIR MEASUREMENT; VARIANT AND "OFF-LADDER" ALLELES; ARTIFACTS OF STR ALLELE AMPLIFICATION; NON-TEMPLATE ADDITION; STUTTER PRODUCTS; NULL (SILENT) ALLELES; Reading List and Internet Resources.
  • Chapter 4
  • STR Genotypes: Heterozygote Balance, Stochastic Thresholds, Allele, and Concordance StudiesIMPORTANCE OF GENOTYPES VS. ALLELES; PEAK HEIGHT RATIOS; STOCHASTIC THRESHOLDS AND ALLELE DROP-OUT; CONCORDANCE STUDIES AND NULL ALLELES; Reading List and Internet Resources; Chapter 5
  • STR Profiles: Multiplex PCR, Tri-Alleles, Amelogenin, and Partial Profiles; INTRODUCTION; MULTIPLEX PCR CHALLENGES; STR PROFILE EVALUATION; TRI-ALLELIC PATTERNS; GENDER IDENTIFICATION WITH AMELOGENIN; PARTIAL DNA PROFILES; Reading List and Internet Resources; Chapter 6
  • DNA Mixtures; GENERAL INFORMATION.
  • TOOLS FOR MIXTURE INTERPRETATIONELEMENTS OF MIXTURE INTERPRETATION; RESOURCES AND GUIDANCE ON MIXTURE INTERPRETATION; COMPLICATING FACTORS IN MIXTURE DECONVOLUTION; Reading List and Internet Resources; Tools for Mixture Interpretation; Elements of Mixture Interpretation; Resources to Aid Mixture Interpretation; Chapter 7
  • Low-Level DNA and Complex Mixtures; INTERPRETATION CHALLENGES WITH LOW TEMPLATE DNA; LOW-QUANTITY AND LOW-QUALITY DNA; PROBABILISTIC GENOTYPING; HIGH-DENSITY SNP ARRAYS?; MORE POOR-QUALITY SAMPLES BEING SUBMITTED; A COMPLEXITY THRESHOLD?; Reading List and Internet Resources.
  • Chapter 8
  • Troubleshooting Data CollectionINTRODUCTION; PRINCIPLES AND PROCESSES INVOLVED WITH CAPILLARY ELECTROPHORESIS; INSTRUMENT MAINTENANCE & COMMON PROBLEMS; RECOMMENDED STEPS FOR TROUBLESHOOTING; SUMMARY; Reading List and Internet Resources; SECTION II
  • STATISTICALINTERPRETATION; Chapter 9
  • Statistical Interpretation Overview; ROLE OF STATISTICS IN FORENSIC DNA; PROBABILITY; STATISTICS; Reading List and Internet Resources; Chapter 10
  • STR Population Data Analysis; INTRODUCTORY GENETIC PRINCIPLES; POPULATION DATA; GENETIC MODELS AND FORMULAS; PRACTICAL CONSIDERATIONS; SUMMARY.

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