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Leprosy : epidemiology, treatment strategies and current challenges in research /
Leprosy is a chronic granulomatous infectious disease that affects the skin and peripheral nerves; its causative agent is the obligate intracellular bacillus Mycobacterium leprae. The etiological diagnosis of the disease in its paucibacillary (PB) form still needs to be improved, because the bacillu...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York :
Nova Biomedical,
[2014]
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| Colección: | Allergies and infectious diseases.
Nova biomedical. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- LEPROSY: EPIDEMIOLOGY, TREATMENT STRATEGIES AND CURRENT CHALLENGES IN RESEARCH; LEPROSY: EPIDEMIOLOGY, TREATMENT STRATEGIES AND CURRENT CHALLENGES IN RESEARCH; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Chapter 1: Leprosy: From Clinical Diagnosis to Benchwork; Abstract; PCR with Primers for MntH (ML2098) Gene Amplification Sensitively and Specifically Identifies M. Leprae in Human Samples; References; Leprosy and Thromboembolic Phenomena; References; Genetic Markers on Leprosy.
- Association of the Solute Carrier Family 11 Member 1 Gene (SLC11A1/NRAMP1) polymorphisms with Susceptibility to LeprosyReferences; Genetic Polymorphisms of Innate and Adaptive Immune Response and Susceptibility to Leprosy; Conclusion; Acknowledgments; References; Chapter 2: In Vivo and In Vitro Evidence on the Relationship between Antiphospholipid Antibodies and Leprosy; Abstract; Introduction; Prevalence of aPL in Leprosy; Specificity of aPL in Leprosy Patients; Do aPL Positive Leprosy Patients Share Páthogenic Mechanisms with APS Patients?; In Vivo Studies Linking aPL with Leprosy.
- ConclusionReferences; Chapter 3: Leprosy and Pregnancy: A Epidemiological and Social Study in the Pará State, North of Brazil; Abstract; Introduction; Concept and Etiology; Classification
- Clinic
- Reactions; Treatment and Prophylactic Actions; Surveillance of Leprosy; Leprosy and Pregnancy; References; Chapter 4: The Potential of Antimicrobial Peptide Inhibitors (APIs) and Elicitors (APEs) in Leprosy Treatment; Abstract; Introduction; Side Effects in the Traditional; Treatment of Leprosy; The Role of Antimicrobial Peptides in Leprosy; Role of Defensins; Role of Hepcidin.
- Role of Cathelicidin LL-37Antimicrobial Peptide Inhibitors; As Potential Treatment of Leprosy; Antimicrobial Peptide Elicitors; As Potential Treatment of Leprosy; Conclusion; Acknowledgments; References; Index.