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Dynamics of cancer : mathematical foundations of oncology /
The book aims to provide an introduction to mathematical models that describe the dynamics of tumor growth and the evolution of tumor cells. It can be used as a textbook for advanced undergraduate or graduate courses, and also serves as a reference book for researchers. The book has a strong evoluti...
| Clasificación: | Libro Electrónico |
|---|---|
| Autores principales: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
[Hackensack] New Jersey :
World Scientific,
2014.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- 1. Teaching guide
- 2. Cancer and somatic evolution
- 3. Mathematical modeling of tumorigenesis
- 4. Single species growth
- 5. Two-species competition dynamics
- 6. Competition between genetically stable and unstable cells
- 7. Chromosomal instability and tumor growth
- 8. Angiogenesis, inhibitors, promoters, and spatial growth
- 9. Evolutionary dynamics of tumor initiation through oncogenes: the gain-of-function model
- 10. Evolutionary dynamics of tumor initiation through tumor-suppressor genes: the loss-of-function model and stochastic tunneling
- 11. Microsatellite and chromosomal instability in sporadic and familial colorectal cancers
- 12. Evolutionary dynamics in hierarchical populations
- 13. Spatial evolutionary dynamics of tumor initiation
- 14. Complex tumor dynamics in space
- 15. Stochastic modeling of cancer growth, treatment, and resistance generation
- 16. Evolutionary dynamics of drug resistance in chronic myeloid leukemia
- 17. Evolutionary dynamics of stem-cell driven tumor growth
- 18. Tumor growth kinetics and disease progression
- 19. Epigenetic changes and the rate of DNA methylation
- 20. Telomeres and cancer protection
- 21. Gene therapy and oncolytic virus therapy
- 22. Immune responses, tumor growth, and therapy
- 23. Towards higher complexities: social interactions.