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Advanced textbook on gene transfer, gene therapy, and genetic pharmacology : principles, delivery, and pharmacological and biomedical applications of nucleotide-based therapies /
This unique advanced textbook provides a clear and comprehensive description of the field of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, along with safety considerations. The use of gene tra...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London :
Imperial College Press,
[2014]
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| Colección: | ICP textbooks in biomolecular sciences ;
1. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- pt. I. Basic definitions and principles. ch. 1. Introduction / Thierry VandenDriessche
- ch. 2. Basic definitions and general principles / Daniel Scherman
- ch. 3. History of gene therapy / Serge Braun
- ch. 4. Genetic pharmacology using synthetic deoxyribonucleotides / Jean-Christophe Francois and Carine Giovannangeli
- ch. 5. Principles of RNAi trigger expression for gene therapy / Lisa J. Scherer and John J. Rossi
- ch. 6. On demand alternative splicing for gene rescue / Stephanie Lorain and Luis Garcia
- ch. 7. Nuclease-mediated targeted genetic correction / Dieter C. Gruenert, Hamid Emamekhoo and R. Geoffrey Sargent
- pt. II. Vectors and gene delivery techniques. ch. 8. [symbol]-retrovirus- and lentivirus-derived vectors for gene transfer and therapy / Caroline Duros and Odile Cohen-Haguenauer
- ch. 9. Adenovirus vectors / Stefan Kochanek
- ch. 10. Adeno-Associated Virus (AAV) vectors / Aurelie Ploquin, Hildegard Buning and Anna Salvetti
- ch. 11. Herpes Simplex Virus (HSV-1)-based vectors: Applications for gene transfer, gene therapy, cancer virotherapy and vaccination / Matias E. Melendez [and others]
- ch. 12. Non-viral DNA vectors / Martin Schleef
- ch. 13. Macromolecular conjugates for non-viral nucleic acid delivery / Mark Ericson, Kevin Rice and Guy Zuber
- ch. 14. Auto-associative lipid-based systems for non-viral nucleic acid delivery / Virginie Escriou, Nathalie Mignet and Andrew Miller
- ch. 15. Hydrodynamic-pressure-based non-viral nucleic acid delivery / Takeshi Suda
- ch. 16. Electrotransfer/electroporation for non-viral nucleic acid delivery / Pascal Bigey, Richard Heller and Daniel Scherman
- ch. 17. Imaging of gene delivery / Georges Vassaux [and others]
- pt. III. Therapeutic applications. ch. 18. Oncolytic adenoviruses for cancer gene therapy / Gunnel Hallden [and others]
- ch. 19. Progress in DNA vaccine approaches for cancer immunotherapy / Geoffrey D. Hannigan and David B. Weiner
- ch. 20. Gene therapy of the beta-hemoglobinopathies / Emmanuel Payen [and others]
- ch. 21. Gene therapy for hemophilia A and B / Nisha Nair, Marinee Chuah and Thierry VandenDriessche
- ch. 22. Experimental and clinical ocular gene therapy / Alexis-Pierre Bemelmans and Jose-Alain Sahel
- ch. 23. Gene therapy of neurological diseases / Lisa M. Stanek, Lamya S. Shihabuddin and Seng H. Cheng
- ch. 24. Genetic therapy of muscle diseases: Duchenne muscular dystrophy / Takis Athanasopoulos [and others]
- ch. 25. Induced pluripotent stem cells and gene targeting for regenerative medicine / Jizhong Zou and Linzhao Cheng
- pt. IV. Gene vector production. ch. 26. Production and purification of viral vectors and safety considerations related to their use / Otto-Wilhelm Merten [and others]
- ch. 27. Production and purification of plasmid vectors / Martin Schleef.