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The spectrum of mineral and bone disorders in chronic kidney disease /

This new edition is fully updated to reflect the most current thinking and understanding in the field, as presented by a team of international clinical experts.

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Olgaard, Klaus, Salusky, Isidro B., Silver, Justin, 1943-
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Oxford ; New York : Oxford University Press, [2010]
Edición:Second edition.
Colección:Oxford clinical nephrology series.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 4 |a The spectrum of mineral and bone disorders in chronic kidney disease /  |c edited by Klaus Olgaard, Isidro B. Salusky, Justin Silver. 
250 |a Second edition. 
264 1 |a Oxford ;  |a New York :  |b Oxford University Press,  |c [2010] 
264 4 |c ©2010 
300 |a 1 online resource (xxvi, 590 pages) :  |b illustrations (some color) 
336 |a text  |b txt  |2 rdacontent 
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490 1 |a Oxford clinical nephrology series 
500 |a Revised edition of: The spectrum of renal osteodystrophy / edited by Tilman Drüeke, Isidro B. Salusky. c2001. 
504 |a Includes bibliographical references and index. 
588 0 |a Print version record. 
520 8 |a This new edition is fully updated to reflect the most current thinking and understanding in the field, as presented by a team of international clinical experts. 
505 0 |a Contributors; List of Abbreviations; Introduction; 1 Definition and classification of renal osteodystrophy and chronic kidney disease-mineral bone disorder (CKD-MBD); Renal osteodystrophy; Chronic kidney disease-mineral bone disorder; Conclusion; References; 2 New aspects of normal bone biology; Introduction; Osteoclasts; Osteoblasts; Osteocytes; Systemic hormones; Summary; References; 3 Osteocytes and mineral metabolism; Introduction; The osteoblast/osteocyte lineage; Osteocyte role in mineralization; Roles of osteocytes in the control of Pi homeostasis 
505 8 |a Osteocytes' role in phosphate dysregulation associated with CKDThe influence of CKD on osteocyte function; Summary; References; 4 Calcium-sensing receptors (CaSR) in kidney, bone, and vessels; Introduction; Expression, structure, and signaling of the extracellular CaSR; CaSR in the kidney; CaSR and bone; The CaSR and blood vessels; Summary; References; 5 Regulation of parathyroid hormone biosynthesis and gene expression; Introduction; Regulation of PTH expression by 1,25(OH)[sub(2)] vitamin D; Post-transcriptional regulation of PTH gene expression by calcium, phosphate, and CKD 
505 8 |a Fibroblast growth factor-23 and PTH gene expressionConclusions; References; 6 Abnormal parathyroid gland function in CKD; Introduction; Regulation of PTH gene transcription in CKD; Regulation of PTH release in CKD; Phosphate and abnormal PTH synthesis and secretion in CKD; Vitamin D and abnormal PTH synthesis and secretion in CKD; Abnormal PTH synthesis and secretion due to other factors; Post-transcriptional modulation of PTH synthesis in CKD; Changes in the intracellular and peripheral metabolism of PTH in CKD; Hyperplasia of parathyroid glands in CKD 
505 8 |a Parathyroid function and VDR polymorphismsControl of increased parathyroid mass; Parathyroid tissue apoptosis and necrosis; Summary; References; 7 PTHrP physiology and pathophysiology, and the PTH/PTHrP receptor; Introduction; Characteristics of the PTHrP gene; Regulation of PTHrP production; Processing and degradation of PTHrP; Physiological actions of PTHrP; Mechanisms of action of PTHrP; PTH/PTHrP receptor expression in renal osteodystrophy; Summary; References; 8 Vitamin D metabolism and action in CKD; Introduction; 25-Hydroxyvitamin D deficiency in CKD; Calcitriol production in CKD 
505 8 |a The vitamin D receptorEffects of declining 1,25-dihydroxyvitamin D on mineral metabolism; Non-traditional actions of vitamin D; Cardiac effects of calcitriol; Vitamin D and the immune system; Additional effects of vitamin D; Vitamin D and survival in CKD; Summary; References; 9 Growth factors and cytokines in renal bone disease; Introduction; The cells of bone; Bone remodeling; Effects of uremia on skeletal biology; References; 10 Bone histomorphometry in renal osteodystrophy; Historical perspective of renal osteodystrophy; Pathology of different forms of renal osteodystrophy 
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650 0 |a Renal osteodystrophy. 
650 1 2 |a Chronic Kidney Disease-Mineral and Bone Disorder 
650 2 2 |a Renal Insufficiency, Chronic  |x complications 
650 6 |a Ostéodystrophie rénale. 
650 7 |a HEALTH & FITNESS  |x Diseases  |x General.  |2 bisacsh 
650 7 |a MEDICAL  |x Clinical Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Diseases.  |2 bisacsh 
650 7 |a MEDICAL  |x Evidence-Based Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Internal Medicine.  |2 bisacsh 
650 7 |a Renal osteodystrophy  |2 fast 
650 7 |a Chronische Niereninsuffizienz  |2 gnd 
650 7 |a Knochenstoffwechsel  |2 gnd 
650 7 |a Mineralstoffwechselstörung  |2 gnd 
700 1 |a Olgaard, Klaus. 
700 1 |a Salusky, Isidro B. 
700 1 |a Silver, Justin,  |d 1943- 
730 0 |a Spectrum of renal osteodystrophy. 
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