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Progenitor cells : biology, characterization and potential clinical applications /
In this book, the authors present current research in the study of the biology, characterization and potential clinical application of progenitor cells. Topics discussed include endothelial progenitor cells and cardiovascular disease; isolation, expansion and clinical therapy of human corneal epithe...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York :
Nova Biomedical,
[2013]
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| Colección: | Cell biology research progress.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- PROGENITOR CELLS: BIOLOGY, CHARACTERIZATION AND POTENTIAL CLINICAL APPLICATIONS; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Chapter 1: Endothelial Progenitor Cells and Cardiovascular Disease; Abstract; 1. Introduction; 2. Correlation between EPCs and Other Cardiovascular Risk Markers; 3. EPCs in Patients with Established Cardiovascular Disease; 4. Reversible Defects in EPC Number and Function in Patients with an Increased Cardiovascular Risk; 5. Statins and EPC Biology; 6. The Effect on EPCs of Other Interventions Known to Reduce Cardiovascular Risk.
- 7. Beneficial Effects of Infusion of EPCs in Animal Models of Ischaemia8. Human Studies of EPC Administration; Conclusion; References; Chapter 2: Characterization, Isolation, Expansion and Clinical Therapy of Human Corneal Epithelial Stem/Progenitor Cells; Abstract; Concept of Tissue Specific Adult Stem Cells and Progenitor Cells; Human Corneal Epithelial Stem/Progenitor Cells; The Phenotype of Corneal Epithelial Progenitor Cells; Isolation and Expansion of Corneal Epithelial Progenitor Cells; Corneal Epithelial Stem Cell Deficiency.
- Progenitor Cell Therapy and Tissue Engineering for Corneal ReconstructionConclusion; References; Chapter 3: Genetically Engineered Blood Pharming: Generation of HLA Universal Platelets Derived from CD34+ Progenitor Cells; Abstract; Introduction; Generation of Platelets In Vitro; Platelet Transfusion Refractoriness; Isolation and Culture of CD34+ Progenitor Cells; Generation of HLA Universal Platelets; HLA-Universal Megakaryocytes Are Protected from Antibody-Mediated Complement-Dependent Cytotoxicity In Vitro.
- HLA-Universal Megakaryocytes Increase Human PLT Counts in Mice Refractory to Human PLTSConclusion; References; Chapter 4: Regulation of Neural Progenitor Cells by Wnt5a-Signaling in the Developmental Central Nervous System; Abstract; 1. Introduction; 2. Wnt5a-Ror signaling in Neocortical NPCs; 3. Cooperative Function of Wnt5a signaling with Wnt/b-catenin Signaling in Midbrain NPCs; 4. Function of Dlx-induced Expression of Wnt5a in GABAergic Interneuron Progenitors of the Olfactory Bulb (OB); Conclusion; Acknowledgments; References; Chapter 5: Endothelial Progenitor Cells in Clinical Settings.
- AbstractIntroduction; Contribution of EPC to Endothelial Cell Repair and Vascular Cell Senescence; Angiogenic Cytokines and Clinical Outcome; Vascular Endothelial Growth Factor (VEGF); Fibroblast Growth Factor (FGF); Hepatocyte Growth Factor (HGF); HGF, But Not VEGF and FGF, Prevent Inflammation, Cell Senescence, and Tissue Fibrosis; Future Perspective; Acknowledgment; Sources of Funding; Disclosures; References; Chapter 6: Role of MicroRNAs in Endothelial Progenitor Cells: Implication for Cardiac Repair; Abstract; 1. Introduction; 2. MicroRNAs; 3. Endothelial Progenitor Cells.