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|a UAMI
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|a Progenitor cells :
|b biology, characterization and potential clinical applications /
|c Patrick M. Horton and Brett E. Lawrence, editors.
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|a New York :
|b Nova Biomedical,
|c [2013]
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|c Ã2013
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|a 1 online resource
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|a text
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|a Cell biology research progress
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|a Includes bibliographical references and index.
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|a Print version record.
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|a PROGENITOR CELLS: BIOLOGY, CHARACTERIZATION AND POTENTIAL CLINICAL APPLICATIONS; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Chapter 1: Endothelial Progenitor Cells and Cardiovascular Disease; Abstract; 1. Introduction; 2. Correlation between EPCs and Other Cardiovascular Risk Markers; 3. EPCs in Patients with Established Cardiovascular Disease; 4. Reversible Defects in EPC Number and Function in Patients with an Increased Cardiovascular Risk; 5. Statins and EPC Biology; 6. The Effect on EPCs of Other Interventions Known to Reduce Cardiovascular Risk.
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|a 7. Beneficial Effects of Infusion of EPCs in Animal Models of Ischaemia8. Human Studies of EPC Administration; Conclusion; References; Chapter 2: Characterization, Isolation, Expansion and Clinical Therapy of Human Corneal Epithelial Stem/Progenitor Cells; Abstract; Concept of Tissue Specific Adult Stem Cells and Progenitor Cells; Human Corneal Epithelial Stem/Progenitor Cells; The Phenotype of Corneal Epithelial Progenitor Cells; Isolation and Expansion of Corneal Epithelial Progenitor Cells; Corneal Epithelial Stem Cell Deficiency.
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|a Progenitor Cell Therapy and Tissue Engineering for Corneal ReconstructionConclusion; References; Chapter 3: Genetically Engineered Blood Pharming: Generation of HLA Universal Platelets Derived from CD34+ Progenitor Cells; Abstract; Introduction; Generation of Platelets In Vitro; Platelet Transfusion Refractoriness; Isolation and Culture of CD34+ Progenitor Cells; Generation of HLA Universal Platelets; HLA-Universal Megakaryocytes Are Protected from Antibody-Mediated Complement-Dependent Cytotoxicity In Vitro.
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|a HLA-Universal Megakaryocytes Increase Human PLT Counts in Mice Refractory to Human PLTSConclusion; References; Chapter 4: Regulation of Neural Progenitor Cells by Wnt5a-Signaling in the Developmental Central Nervous System; Abstract; 1. Introduction; 2. Wnt5a-Ror signaling in Neocortical NPCs; 3. Cooperative Function of Wnt5a signaling with Wnt/b-catenin Signaling in Midbrain NPCs; 4. Function of Dlx-induced Expression of Wnt5a in GABAergic Interneuron Progenitors of the Olfactory Bulb (OB); Conclusion; Acknowledgments; References; Chapter 5: Endothelial Progenitor Cells in Clinical Settings.
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|a AbstractIntroduction; Contribution of EPC to Endothelial Cell Repair and Vascular Cell Senescence; Angiogenic Cytokines and Clinical Outcome; Vascular Endothelial Growth Factor (VEGF); Fibroblast Growth Factor (FGF); Hepatocyte Growth Factor (HGF); HGF, But Not VEGF and FGF, Prevent Inflammation, Cell Senescence, and Tissue Fibrosis; Future Perspective; Acknowledgment; Sources of Funding; Disclosures; References; Chapter 6: Role of MicroRNAs in Endothelial Progenitor Cells: Implication for Cardiac Repair; Abstract; 1. Introduction; 2. MicroRNAs; 3. Endothelial Progenitor Cells.
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|a In this book, the authors present current research in the study of the biology, characterization and potential clinical application of progenitor cells. Topics discussed include endothelial progenitor cells and cardiovascular disease; isolation, expansion and clinical therapy of human corneal epithelial stem/progenitor cells; genetically engineered blood pharming; regulation of neural progenitor cells by Wnt5a-signaling in the developmental central nervous system; endothelial progenitor cells in a clinical setting; role of microRNAs in endothelial progenitor cells and their implication for car.
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|a Stem cells.
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|a Horton, Patrick M.,
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|a Lawrence, Brett E.,
|e editor.
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|i Print version:
|t Progenitor cells.
|d New York : Nova Biomedical, [2013]
|z 9781628089943
|w (DLC) 2013948183
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|a Cell biology research progress.
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