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Vincristine : clinical uses, pharmacokinetics, and impacts on health /

Vincristine is a naturally occurring alkaloid isolated from the leaves of the plant Catharanthus roseus. It has a wide range of clinical applications. Extracts of the plant have found application in wound healing, in the treatment of diabetic ulcers and diabetes mellitus, and in cancer chemotherapy....

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Coello, Juan M. (Editor ), Sabres, Yolanda D. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : Nova Biomedical, [2013]
Colección:Pharmacology-research, safety testing, and regulation series.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • ""VINCRISTINE: CLINICAL USES, PHARMACOKINETICS AND IMPACTS ON HEALTH""; ""VINCRISTINE: CLINICAL USES, PHARMACOKINETICS AND IMPACTS ON HEALTH""; ""Library of Congress Cataloging-in-Publication Data""; ""Contents""; ""Preface""; ""Chapter 1: Vincristine as an Inductor of Drug Resistance Marker Expression in Neoplastic Cells""; ""Abstract""; ""Biochemical Characterization of P-Glycoprotein and Multidrug Resistance Associated Proteins""; ""Vincristine As Inductor of P-gp and MRPs â€? Insight to Drug Sensitivity of Cells""
  • ""Cellular Modification of Vincristine and Vincristine-Induced Free Radical Formation â€? Insight into the Drug Sensitivity of Cells""""Effects of Vincristine on Cell Signalization â€? Insight to the Drug Sensitivity of Cells""; ""Conclusion""; ""Acknowledgments""; ""References""; ""Chapter 2: Clinical Utility of Vincristine in the Treatment of Human Carcinomas""; ""Abstract""; ""Introduction""; ""History of Vincristine""; ""Molecular Characteristics of Vincristine""; ""Clinical Pharmacology of Vincristine""; ""Clinical Use of Vincristine""; ""Vincristine Toxicity""; ""Conclusion""