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Ribavirin : biochemistry, clinical applications and potential side effects /
Ribavirin has been studied for over 20 years as a potential therapy against a number of RNA and DNA viruses. It is well known that Ribavirin in combination with Interferon is a key antiviral component in the treatment of Hepatitis C virus infection. In this book, the authors discuss the biochemistry...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
[Hauppauge] New York :
Nova Biomedical,
[2013]
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| Colección: | Pharmacology-research, safety testing, and regulation series.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- RIBAVIRIN. BIOCHEMISTRY, CLINICAL APPLICATIONS AND POTENTIAL SIDE EFFECTS; RIBAVIRIN. BIOCHEMISTRY, CLINICAL APPLICATIONS AND POTENTIAL SIDE EFFECTS; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Chapter 1: Optimizing Ribavirin Usefor the Treatment of Hepatitis C; Abstract; Introduction; Hepatitis C (HCV); The Evolution of HCV Treatment -The Importance of RBV; Why Was New Treatment Discovery for HCV Hampered?; The Direct Acting Antiviral (DAA) Era; Pharmacokinetics of RBV; RBV -Induced Hemolytic Anemia; Identification of the Inosine Triphosphatase Gene.
- Mechanism of Action of Ribavirin in HCVThe Importance of RBV Adherence; The Importance of Pill Burden and Dosing Frequency on Medication Adherence; RBV QD vs. BID Dosing; Summary of Once Daily DAA trials; Conclusion; References; Chapter 2: Ribavirin and its Great Potentials in Infectious Diseases; Abstract; Introduction; Structure; History; Metabolism; Mechanism of Action; Spectrum of Action; Anticancer Role; Ribavirin Derivatives; Ribavirin and HCV; Ribavirin Side Effects; References; Chapter 3: Antiviral Actions of Ribavirin; Abstract; Introduction.
- 1. Biochemistry, Pharmacokinetics and Mechanism of Action2. Clinical Applications; 3. Potential Side Effects; References; Chapter 4: A Novel Prediction Method for the Responsiveness of Hepatitis C Patients to Drug Treatment; Abstract; 1. Introduction; 2. Materials and Methods; 3. Results and discussion; Acknowledgments; References; Chapter 5: Ribavirin Intolerable Cough during HCV Combination Therapy Can Be Overcome by Nitazoxanide Replacement; Abstract; Introduction; Case Presentation; Discussion; Conclusion; References; Index.