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Impedimetric biosensors for medical applications : current progress and challenges /

In this monograph, the authors discuss the current progress in the medical application of impedimetric biosensors, along with the key challenges in the field. First, a general overview of biosensor development, structure and function is presented, followed by a detailed discussion of impedimetric bi...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores principales: Rushworth, Jo V. (Autor), Hirst, Natalie A. (Autor), Goode, Jack A. (Autor), Pike, Douglas J. (Autor), Ahmed, Asif (Autor), Millner, Paul A. (Autor)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : ASME Press : Momentum Press, [2013]
Colección:Biomedical & nanomedical technologies.
Temas:
Acceso en línea:Texto completo

MARC

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100 1 |a Rushworth, Jo V.,  |e author. 
245 1 0 |a Impedimetric biosensors for medical applications :  |b current progress and challenges /  |c Jo V. Rushworth, Natalie A. Hirst, Jack A. Goode, Douglas J. Pike, Asif Ahmed, Paul A. Millner. 
264 1 |a New York, NY :  |b ASME Press :  |b Momentum Press,  |c [2013] 
300 |a 1 online resource (70 pages) :  |b illustrations 
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337 |a computer  |b c  |2 rdamedia 
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490 1 |a Biomedical and nanomedical technologies 
504 |a Includes bibliographical references (pages 57-70). 
505 0 |a 1. Introduction and scope. 
505 8 |a 2. Biosensors -- 2.1 Brief history of biosensor development -- 2.2 Applications of biosensors -- 2.3 Biosensor architecture, an overview -- 2.4 Biorecognition element -- 2.5 Transducer element -- 2.6 Summary. 
505 8 |a 3. Electrochemical impedance spectroscopy -- 3.1 Brief history of the development of impedimetric biosensors -- 3.2 An overview of impedance -- 3.3 Principles of impedimetric sensing -- 3.4 Presenting and analysing impedance data. 
505 8 |a 4. Fabrication of impedimetric biosensors -- 4.1 Electrode design and materials -- 4.2 Bioreceptor tethering to transducer surfaces. 
505 8 |a 5. Commercializing impedimetric biosensors: from laboratory to field -- 5.1 Components of a point-of-care diagnostic device -- 5.2 From research to point-of-care -- 5.3 Sample delivery & processing -- 5.4 Sensor regeneration -- 5.5 Barriers to commercialisation. 
505 8 |a 6. Case studies of impedimetric biosensors for medical applications -- 6.1 Whole cells and pathogenic microorganisms -- 6.2 Protein and peptide biomarkers of disease -- 6.3 Small molecules. 
505 8 |a 7. Conclusions and future perspectives. 
505 8 |a 8. Author biographies -- References. 
520 3 |a In this monograph, the authors discuss the current progress in the medical application of impedimetric biosensors, along with the key challenges in the field. First, a general overview of biosensor development, structure and function is presented, followed by a detailed discussion of impedimetric biosensors and the principles of electrochemical impedance spectroscopy. Next, the current state-of-the art in terms of the science and technology underpinning impedance-based biosensors is reviewed in detail. The layer- by-layer construction of impedimetric sensors is described, including the design of electrodes, their nano-modification, transducer surface functionalisation and the attachment of different bioreceptors. The current challenges of translating lab-based biosensor platforms into commercially-available devices that function with real patient samples at the POC are presented; this includes a consideration of systems integration, microfluidics and biosensor regeneration. The final section of this monograph describes case studies of successful impedance-based biosensors for the detection of a range of analytes from small molecules up to whole microorganisms. Finally, the authors put forward future perspectives for the clinical applications of impedimetric biosensors. 
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650 0 |a Biosensors. 
650 0 |a Impedance spectroscopy. 
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650 2 |a Electric Impedance 
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650 6 |a Spectroscopie d'impédance. 
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650 7 |a MEDICAL  |x Osteopathy.  |2 bisacsh 
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650 7 |a Impedance spectroscopy.  |2 fast  |0 (OCoLC)fst00968092 
700 1 |a Hirst, Natalie A.,  |e author. 
700 1 |a Goode, Jack A.,  |e author. 
700 1 |a Pike, Douglas J.,  |e author. 
700 1 |a Ahmed, Asif,  |e author. 
700 1 |a Millner, Paul A.,  |e author. 
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