Females are mosaics : X inactivation and sex differences in disease /

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Women can be described as genetic mosaics because they have two distinctly different types of cells throughout their bodies. Unlike males, who have one X chromosome, females have two X chromosomes in every cell. Much has been written about the Y chromosome and its role in inducing maleness. This is...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Migeon, Barbara R.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Oxford : Oxford University Press, 2014.
Edición:Second edition.
Temas:
X chromosome.
Mosaicism.
Genetic sex determination.
Sex-linkage (Genetics)
Sex factors in disease.
Mosaicism
X Chromosome Inactivation > physiology
Genetic Diseases, X-Linked
Sex Factors
X Chromosome
Chromosome X.
Mosaïcisme.
Sexe > Détermination génétique.
Hérédité liée au sexe.
Maladies > Facteurs sexuels.
HEALTH & FITNESS > Diseases > General.
MEDICAL > Clinical Medicine.
MEDICAL > Diseases.
MEDICAL > Evidence-Based Medicine.
MEDICAL > Internal Medicine.
Sex factors in disease
Genetic sex determination
X chromosome
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Sex differences in disease
  • Evolution of the human sex chromosomes and a portrait of the human X
  • X chromosome dosage compensation : an overview
  • The discovery of X chromosome inactivation
  • Experimental models for X inactivation studies
  • Theme 1 : the initial step : creating the active and inactive X
  • Theme 2 : subsequent steps : spreading and maintaining inactivation
  • Variations 1 : evolution of the X inactivation center
  • Variations 2 : stability of the inactive X
  • Variations 3 : choice of active X
  • The single active X
  • Mosaicism
  • Epimutations, chromatin disorders and sex differences in phenotype
  • Determinants of female phenotypes.

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