Cargando…
Microfluidics, nanotechnology and disease biomarkers for personalized medicine applications /
In recent years, thousands of cancer biomarkers have been discovered and described in scientific literature. The promise of personalized medicine, where diseases such as cancer are accurately diagnosed and treatments tailored specifically for individuals, is becoming a reality. Significant advances...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York :
Nova Biomedical,
[2013]
|
| Colección: | New developments in medical research.
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
| LEADER | 00000cam a2200000 i 4500 | ||
|---|---|---|---|
| 001 | EBSCO_ocn857878864 | ||
| 003 | OCoLC | ||
| 005 | 20231017213018.0 | ||
| 006 | m o d | ||
| 007 | cr ||||||||||| | ||
| 008 | 130506s2013 nyu ob 001 0 eng | ||
| 010 | |a 2020677817 | ||
| 040 | |a DLC |b eng |e rda |e pn |c DLC |d AUM |d N$T |d OCLCF |d EBLCP |d AGLDB |d OTZ |d VTS |d STF |d M8D |d VLY |d YDXCP |d OCLCO |d UV0 |d AJS |d OCLCQ |d OCLCO |d OCLCQ | ||
| 019 | |a 864793318 |a 923670657 |a 928194283 | ||
| 020 | |a 9781628080209 |q (hardcover) | ||
| 020 | |a 1628080205 | ||
| 020 | |a 9781628080391 |q (ebook) | ||
| 020 | |a 1628080396 |q (electronic bk.) | ||
| 020 | |a 9781628080391 |q (electronic bk.) | ||
| 029 | 1 | |a AU@ |b 000052305167 | |
| 029 | 1 | |a AU@ |b 000060903285 | |
| 029 | 1 | |a DEBBG |b BV043777204 | |
| 029 | 1 | |a DEBSZ |b 450736326 | |
| 029 | 1 | |a NZ1 |b 15212907 | |
| 035 | |a (OCoLC)857878864 |z (OCoLC)864793318 |z (OCoLC)923670657 |z (OCoLC)928194283 | ||
| 050 | 0 | 0 | |a TJ853.4.M53 |
| 072 | 7 | |a TEC |x 009000 |2 bisacsh | |
| 072 | 7 | |a TEC |x 035000 |2 bisacsh | |
| 082 | 0 | 4 | |a 620.1/06 |2 23 |
| 049 | |a UAMI | ||
| 245 | 0 | 0 | |a Microfluidics, nanotechnology and disease biomarkers for personalized medicine applications / |c Muhammad J.A. Shiddiky, Eugene J.H. Wee, Sakandar Rauf, and Matt Trau, editors. |
| 264 | 1 | |a New York : |b Nova Biomedical, |c [2013] | |
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a New Developments in Medical Research | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 505 | 0 | |a MICROFLUIDICS, NANOTECHNOLOGY AND DISEASE BIOMARKERS FOR PERSONALIZED MEDICINE APPLICATIONS -- MICROFLUIDICS, NANOTECHNOLOGY AND DISEASE BIOMARKERS FOR PERSONALIZED MEDICINE APPLICATIONS -- Library of Congress Cataloging-in-Publication Data -- CONTENTS -- PREFACE -- Chapter 1 BIO-MEMS (MICROFLUIDICS) FOR CTC DETECTION IN CANCER PATIENTS -- ABSTRACT -- 1. INTRODUCTION -- 1.1. Circulating Tumor Cells as Driving Force in Cancer Metastasis -- 1.2. Clinical Implications of CTCs -- 2. ADVENT OF MICROFLUIDICS FOR CTC ISOLATION AND DETECTION | |
| 505 | 8 | |a 2.1. Microfluidic Technologies for Isolation of Circulating Tumor Cells (CTCs) 2.1.1. Immunoaffinity-Based Isolation -- 2.1.2. Label-Free Separation -- 2.2. Integrated Technologies -- 3. APPLICATIONS FOR DIAGNOSIS, MONITORING, AND PROGNOSIS -- 3.1. Early Detection/Screening -- 3.2. Monitoring Patients for Treatment Efficacy and Relapse -- 3.3. Prognosis -- 4. UNDERSTANDING FUNDAMENTAL BIOLOGY OF CANCER -- 4.1. Functional CTC Assays for Cancer Biology -- 4.2. Therapeutic Targeting of CTCs -- 5. PREDICTIVE BIOMARKERS DISCOVERY AND PERSONALIZED THERAPIES | |
| 505 | 8 | |a 6. CURRENT CHALLENGES AND FUTURE DIRECTIONS CONCLUSION -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 2 MICROFLUIDIC FLOW FRACTIONATION FOR ISOLATION OF CIRCULATING TUMOR CELLS -- ABSTRACT -- 1. INTRODUCTION -- 2. SINGLE MULTI-ORIFICE FLOW FRACTIONATION (S-MOFF) -- 2.1. Theory and Mechanism of Separation -- 2.2. Analysis of Particle Distribution -- 2.2.1. Microparticles Migration through the Multi-Orifice Microchannel -- 2.2.2. Visualization and Analysis of Particle Distribution -- 3. MULTISTAGE MULTI-ORIFICE FLOW FRACTIONATION (MS-MOFF) | |
| 505 | 8 | |a 3.1. Development of MS-MOFF Device 3.2. Equivalent Circuit Analysis -- 3.3. Separation Yield of Multi-Stage Channel -- 4. MULTI-ORIFICE FLOW FRACTIONATION PLUS DIELECTROPHORESIS (MOFF+DEP) -- 4.1. Development of MOFF+DEP Device -- 4.2. Continuous Separation of Breast Cancer Cells from Blood Samples -- 4.2.1. Hydrophoretic Cell Separation -- 4.2.2. Dielectrophoretic Cell Separation -- 5. A PARALLEL MULTI-ORIFICE FLOW FRACTIONATION (P-MOFF) -- 5.1. Development of p-MOFF Device -- 5.2. Isolation and Enumeration of CTCs from Breast Cancer Patients | |
| 505 | 8 | |a CONCLUSION REFERENCES -- Chapter 3 MICRO/NANOSTRUCTURED SUBSTRATES FOR CELL TYPING, ISOLATION AND DISEASE DIAGNOSTICS -- ABSTRACT -- 1. INTRODUCTION -- 2. MECHANICAL AND HYDRODYNAMIC SEPARATION -- 3. AFFINITY BASED ASSAYS -- 4. DIELECTROPHORESIS (DEP) -- 5. MAGNETIC ISOLATION -- CONCLUSION -- REFERENCES -- Chapter 4 MICROFLUIDIC DEVICES FOR THE ANALYSIS OF DRUGS AND THEIR METABOLITES IN BIOLOGICAL FLUIDS -- ABSTRACT -- 1. INTRODUCTION -- LIST OF ABBREVIATIONS -- 2. POINT-OF-CARE DEVICES -- 3. MICROFLUIDICS FOR POC DEVICES | |
| 520 | |a In recent years, thousands of cancer biomarkers have been discovered and described in scientific literature. The promise of personalized medicine, where diseases such as cancer are accurately diagnosed and treatments tailored specifically for individuals, is becoming a reality. Significant advances in biomarker-based research methodologies such as Next Generation Sequencing (NGS) are at the cusp of ushering in a new era of personal medicine. However, unlike the spectacular advances in research technologies for disease biomarker discovery, biomarker-based technologies that can effectively be us. | ||
| 590 | |a eBooks on EBSCOhost |b EBSCO eBook Subscription Academic Collection - Worldwide | ||
| 650 | 0 | |a Microfluidics. | |
| 650 | 0 | |a Nanotechnology. | |
| 650 | 6 | |a Microfluidique. | |
| 650 | 7 | |a TECHNOLOGY & ENGINEERING |x Engineering (General) |2 bisacsh | |
| 650 | 7 | |a TECHNOLOGY & ENGINEERING |x Reference. |2 bisacsh | |
| 650 | 7 | |a Biochemical markers. |2 fast |0 (OCoLC)fst00831950 | |
| 650 | 7 | |a Microfluidics. |2 fast |0 (OCoLC)fst01736696 | |
| 650 | 7 | |a Nanotechnology. |2 fast |0 (OCoLC)fst01032639 | |
| 700 | 1 | |a Shiddiky, Muhammad J. A., |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Microfluidics, nanotechnology and disease biomarkers for personalized medicine applications. |d New York : Nova Biomedical, [2013] |z 9781628080209 |w (DLC) 2013939635 |
| 830 | 0 | |a New developments in medical research. | |
| 856 | 4 | 0 | |u https://ebsco.uam.elogim.com/login.aspx?direct=true&scope=site&db=nlebk&AN=635074 |z Texto completo |
| 938 | |a ProQuest Ebook Central |b EBLB |n EBL3023096 | ||
| 938 | |a EBSCOhost |b EBSC |n 635074 | ||
| 938 | |a YBP Library Services |b YANK |n 10794467 | ||
| 994 | |a 92 |b IZTAP | ||