Cargando…

Huntington's disease : symptoms, risk factors and prognosis /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Guillory, Kevin
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Hauppauge, NY : Nova Science Publishers, Inc., 2013.
Colección:Neurodegenerative diseases--laboratory and clinical research.
Temas:
Acceso en línea:Texto completo

MARC

LEADER 00000cam a2200000Ia 4500
001 EBSCO_ocn857060866
003 OCoLC
005 20231017213018.0
006 m o d
007 cr cnu---unuuu
008 111102s2013 nyua ob 001 0 eng d
040 |a E7B  |b eng  |e pn  |c E7B  |d OCLCO  |d N$T  |d YDXCP  |d OCLCA  |d OCLCF  |d GPM  |d EBLCP  |d OCLCQ  |d D6H  |d AGLDB  |d Z5A  |d OCLCQ  |d VTS  |d AU@  |d STF  |d M8D  |d OCLCQ  |d OCLCO  |d OCLCQ  |d OCLCO 
020 |a 9781628083170  |q (electronic bk.) 
020 |a 1628083174  |q (electronic bk.) 
020 |z 9781628083163 
020 |z 9781628083170 
029 1 |a DEBBG  |b BV041572600 
029 1 |a DEBSZ  |b 472796798 
029 1 |a NZ1  |b 15194916 
029 1 |a DEBBG  |b BV043777067 
029 1 |a AU@  |b 000056879262 
029 1 |a AU@  |b 000062327307 
029 1 |a AU@  |b 000065927712 
035 |a (OCoLC)857060866 
050 4 |a RC394.H85  |b G85 2013eb 
072 7 |a HEA  |x 039000  |2 bisacsh 
072 7 |a MED  |x 014000  |2 bisacsh 
072 7 |a MED  |x 022000  |2 bisacsh 
072 7 |a MED  |x 112000  |2 bisacsh 
072 7 |a MED  |x 045000  |2 bisacsh 
082 0 4 |a 616.851  |2 23 
049 |a UAMI 
100 1 |a Guillory, Kevin. 
245 1 0 |a Huntington's disease :  |b symptoms, risk factors and prognosis /  |c Kevin Guillory. 
260 |a Hauppauge, NY :  |b Nova Science Publishers, Inc.,  |c 2013. 
300 |a 1 online resource (ix, 131 pages) :  |b illustrations. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Neurodegenerative diseases - laboratory and clinical research 
504 |a Includes bibliographical references and index. 
505 0 |a HUNTINGTON'S DISEASE ; Library of Congress Cataloging-in-Publication Data ; Contents ; Preface ; Chapter I Huntington's Disease: From Disease Pathogenesisto Clinical Perspectives ; Abstract ; Clinical Features of Huntington's Disease ; Huntingtin's Structure and Post-Translational Modifications ; Htt Function; Molecular Mechanisms of HD Pathogenesis ; Clinical Perspectives in HD ; Conclusion ; Acknowledgments ; Conflict of Interest ; References ; Chapter II The Role of Brain-Derived Neurotrophic Factor (BDNF)in Huntington's Disease: Trophic Support as a Therapeutic Strategy ; Abstract. 
505 8 |a Abbreviations 1. Huntington's Disease ; 2. Brain-Derived Neurotrophic Factor (BDNF) ; 2.1. Neurotrophins ; 2.2. Neurotrophin Receptors and their Normal Functions ; 3. Wild-Type versus Mutant Huntingtin and BDNF ; 3.1. Regulation of BDNF Transcription by Huntingtin ; 3.2. Regulation of BDNF Transport by Huntingtin ; 4. Evidence for Reduced Trophic Support in the HD Brain ; 4.1. Reduction in BDNF Expression in HD Genetic Mouse Models ; 4.2. Reduction in BDNF Expression in the Human HD Brain ; 5. Increasing Trophic Support as a Therapeutic Intervention for HD. 
505 8 |a 5.1. Direct Up-Regulation of Striatal BDNF Levels 5.2. Up-Regulation of BDNF Levels by Pharmacological Strategies ; 5.3. Up-Regulation of BDNF Levels by Non-Invasive Strategies; 5.4. Future Directions ; Conclusion ; Acknowledgments ; References ; Chapter III The Legal Ramifications ofHuntington's Disease ; Author's Note ; Abstract ; Introduction ; Clinical Issues Relevant to the Law ; HD and Insurance ; Imposition of Involuntary Status ; Guardianship Hearings ; Family Law ; Criminal Law ; Probate ; Compensation ; Conclusion ; References ; Index. 
590 |a eBooks on EBSCOhost  |b EBSCO eBook Subscription Academic Collection - Worldwide 
650 0 |a Huntington's disease. 
650 0 |a Brain  |x Diseases. 
650 2 |a Huntington Disease 
650 2 |a Brain Diseases 
650 6 |a Chorée de Huntington. 
650 6 |a Cerveau  |x Maladies. 
650 7 |a HEALTH & FITNESS  |x Diseases  |x General.  |2 bisacsh 
650 7 |a MEDICAL  |x Clinical Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Diseases.  |2 bisacsh 
650 7 |a MEDICAL  |x Evidence-Based Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Internal Medicine.  |2 bisacsh 
650 7 |a Brain  |x Diseases  |2 fast 
650 7 |a Huntington's disease  |2 fast 
830 0 |a Neurodegenerative diseases--laboratory and clinical research. 
856 4 0 |u https://ebsco.uam.elogim.com/login.aspx?direct=true&scope=site&db=nlebk&AN=620153  |z Texto completo 
938 |a ProQuest Ebook Central  |b EBLB  |n EBL3022897 
938 |a ebrary  |b EBRY  |n ebr10740765 
938 |a EBSCOhost  |b EBSC  |n 620153 
938 |a YBP Library Services  |b YANK  |n 10906765 
994 |a 92  |b IZTAP