Tumor necrosis factor : structure, enzyme regulation & role in health & disease /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Escarra, Agueda (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : Nova Science Publishers, ©2013.
Colección:Cell biology research progress.
Temas:
Tumor necrosis factor.
Tumor necrosis factor > Inhibitors.
MEDICAL > Immunology.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • TUMOR NECROSIS FACTOR. STRUCTURE, ENZYME REGULATION AND ROLE IN HEALTH AND DISEASE; TUMOR NECROSIS FACTOR. STRUCTURE, ENZYME REGULATION AND ROLE IN HEALTH AND DISEASE; Library of Congress Cataloging-in-Publication Data; CONTENTS; PREFACE; Chapter 1: TUMOR NECROSIS FACTOR-ALPHA RELATED SIGNAL PATHWAYS AND NEURONAL DISEASES; ABSTRACT; 1. STRUCTURE AND ENZYME REGULATION; 2. THE MOLECULAR MECHANISMS OF TNF- SIGNAL TRANSDUCTION; 3. THERAPEUTIC STRATEGIES IN THE FUTURE STUDIES; REFERENCES; Chapter 2: ROLE OF TNF- IN RHEUMATOID ARTHRITIS; ABSTRACT.
  • PROINFLAMMATORY CYTOKINES IN RHEUMATOID JOINT AND THE IMPORTANCE OF TNFTNF- AND OSTEOCLASTS; TNF- AND TREGS; TNF- AND TH17; TNF- AND MACROPHAGES; TNF- AND FIBROBLASTS; ANTI-TNF- TREATMENT EFFICACY IN HUMANS; THE MECHANISMS IN ANTI-TNF- THERAPY; WHY ARE ANTI-TNF- TREATMENT NON-RESPONDERS?; REFERENCES; Chapter 3: THE ROLE OF TUMOR NECROSIS FACTOR ALPHA IN AUTOIMMUNITY; ABSTRACT; INTRODUCTION; TNF- Ü SIGNAL TRANSDUCTION; TNF- IN RHEUMATOID ARTHRITIS; TNF- IN SYSTEMIC LUPUS ERYTHEMATOSUS; TNF- IN MULTIPLE SCLEROSIS; TNF- INHIBITORS; GRANTS; CONFLICT OF INTEREST; REFERENCES.
  • Chapter 4: THE PRESENCE OF -308A TNF ALLELE IS ASSOCIATED WITH CLINICAL PARAMETERS OF MYELODYSPLASTIC SYNDROMESABSTRACT; INTRODUCTION; MATERIALS AND METHODS; RESULTS; DISCUSSION; ACKNOWLEDGMENTS; REFERENCES; Chapter 5: SIGNIFICANCE OF TNF IN THE IMMUNE RESPONSE AGAINST TUBERCULOSIS; ABSTRACT; INTRODUCTION; MACROPHAGES; TNF POLYMORPHISM; ANTI-TNF TERAPHY AND THE RISK OF TB; CONCLUSION; REFERENCES; Chapter 6: TNF-Ü SIGNALING AND CATHEPSIN B; ABSTRACT; INTRODUCTION; INVOLVEMENT OF CATB IN TNF-Ü-INDUCED APOPTOSIS; INVOLVEMENT OF CATB IN TNF-Ü TRAFFICKING AND SIGNALINGS.
  • INVOLVEMENT OF CATB IN TOLL-LIKE RECEPTOR SINGNALLINGANTI-TNF-Ü AND CATB INHIBITOR THERAPEUTIC APPROACHES; CONCLUSION; REFERENCES; INDEX.

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