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Lung cancer : a comprehensive overview /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Gately, Kathy (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : Nova Biomedical, [2013]
Colección:Cancer etiology, diagnosis, and treatments.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Lung cancer :  |b a comprehensive overview /  |c Kathy Gately, editor. 
264 1 |a New York :  |b Nova Biomedical,  |c [2013] 
300 |a 1 online resource 
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337 |a computer  |b c  |2 rdamedia 
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490 1 |a Cancer etiology, diagnosis and treatments 
504 |a Includes bibliographical references and index. 
588 |a Description based on print version record. 
505 0 |a Intro -- LUNG CANCER: A COMPREHENSIVE OVERVIEW -- Library of Congress Cataloging-in-Publication Data -- Contents -- Preface -- Chapter I: The Pathology of Lung Cancer -- Abstract -- Introduction -- Common Lung Cancers -- Adenocarcinoma -- Squamous Cell Carcinoma -- Distinction of Adenocarcinoma from Squamous Cell Carcinoma on Biopsy Specimens -- Small Cell Carcinoma -- Large Cell Carcinoma -- Neuroendocrine Tumours -- Metastases -- Other Tumours -- Staging -- Molecular Analysis -- Conclusion -- References -- Chapter II: Introduction to Lung Cancer, its Epidemiology and Diagnosis -- Abstract -- Introduction -- International Variation in Lung Cancer Prevalence -- Age and Lung Cancer -- Host Factors and Lung Cancer Risk from Smoking -- Gender Differences in Lung Cancer Incidence -- Race -- Second-Hand Tobacco Smoke -- Non-Smoking Related Exposures for Lung Cancer -- Radon -- Occupational Exposures -- Air Pollutants -- Body Mass Index as a Risk Factor for Lung Cancer -- Non-Cancer Lung Disease -- Genetic Factors in Lung Cancer Risk -- Diagnosis of Lung Cancer -- Symptomatic Lung Cancer Detection -- Asymptomatic Disease: Incidental and Screening Detection -- Diagnosis of Suspected Lung Cancer -- Diagnosis Based on Imaging Characteristics -- Diagnostic Strategies -- Conclusion -- References -- Chapter III: The Effect of Smoking Habit Intensity, Occupation and Diet on Lung Cancer Risk in Males -- Abstract -- Introduction -- Risk Factors -- Tobacco Smoking -- Occupational Exposure -- Diet -- Case Report -- Methods -- Results -- Conclusion -- References -- Chapter IV: Lung Cancer: Treatment in Early Stage -- Abstract -- Introduction -- Adjuvant and Neoadjuvant Therapy for Resectable Non-Small Cell Lung Cancer -- Evidence for Adjuvant CT -- Preoperative CT for Early-Stage NSCLC -- The Role of Adjuvant RT. 
505 8 |a Future Directions: Targeted Therapies and Genetic Predictive and Prognostic Biomarkers -- Conclusion -- References -- Chapter V: Lung Cancer: Treatment in Advanced Stages -- Abstract -- Introduction -- Treatment of Stage III Non-Small Cell Lung Cancer (NSCLC) -- Treatment of Metastatic Non-Small Cell Lung Cancer -- Initial Systemic Therapy for Advanced NSCLC without an EGFR Mutation or the ALK Fusion Oncogene -- Initial Treatment with Targeted Agents -- Second Line Therapy -- Conclusion -- References -- Chapter VI: Management of Stage III N2 NSCLC -- Abstract -- Introduction -- Staging -- Proving N2 Disease -- Treatment -- Goals of Neoadjuvant Therapy -- Current Controversies -- Conclusion -- References -- Chapter VII: Targeted Therapies in Non-Small Cell Lung Cancer -- Abstract -- Introduction -- Targeted Therapy in Lung Cancer -- EGFR -- Targeting EGFR -- VEGF and VEGFR -- Targeting VEGFR with Bevacizumab -- Targeting VEGFR with TKIs -- EML4-ALK -- Targeting EML4-ALK -- KRAS -- Targeting KRAS -- HER2 -- Targeting HER2 -- B-RAF -- Targeting B-RAF -- C-Met -- Targeting C-Met -- PI3K -- Targeting PI3K -- MEK -- Targeting MEK -- PI3K and MEK Co-Targeted Inhibition -- IGF1R -- Targeting IGF1R -- The Future of Targeted Therapy -- Conclusion -- References -- Chapter VIII: Molecular Mechanisms of Cisplatin Resistance in Lung Cancer -- Abstract -- Introduction -- Resistance Mechanisms -- Epigenetic Regulation and Cisplatin Resistance -- Novel Strategies for Overcoming Cisplatin Resistance -- Conclusion -- References -- Chapter IX: Inflammation in Lung Carcinogenesis -- Abstract -- Introduction -- Cancer Related Inflammation -- Lung Cancer and Inflammation -- Inflammatory Mediators In Lung Cancer -- Targeting Inflammation as a Therapeutic Option -- Conclusion -- References. 
505 8 |a Chapter X: The Link between Chronic Obstructive Pulmonary Disease and Lung Cancer: Novel Molecular Insights -- Abstract -- Introduction -- Hazardous Effects of Cigarette Smoking -- Carcinogenic Compounds in the Side-Stream Smoke -- Chronic Inflammation in COPD and Lung Cancer -- Genetics of COPD and Lung Cancer -- Epigenetic Phenomena and Cigarette Smoke -- Conclusion -- References -- Chapter XI: Diagnosis, Treatment and Follow-Up of Neoplastic Pericardial Disease in Lung Cancer -- Abstract -- Introduction -- Diagnosis -- Treatment -- Conclusion -- References -- Chapter XII: The Role of Claudin Proteins in Lung Tumorigenesis -- Abstract -- Introduction -- Claudin Family Proteins -- Post-Translational Modifications of Tight Junction Proteins -- Tight Junction Proteins and Lung Cancer -- Crosstalk of Claudins and Occludin with Other Signaling Pathways in Lung Cancer -- Claudins as Therapeutic Targets -- Conclusion -- Acknowledgments -- References -- Chapter XIII: The Role of the Arachidonic Acid Pathway in NSCLC Development and Progression: Novel Approaches for Therapeutic Intervention -- Abstract -- Introduction -- 1. Arachidonic Acid Metabolism: Generation and Classification of Eicosanoids -- 2. Altered Expression of Arachidonic Acid Signalling in NSCLC -- 3. Effect of the Arachidonic Acid Pathway on Tumour Cell Signalling and Proliferation -- 4. Arachidonic Acid Mediated Regulation of Tumour Cell Death -- 5. The Role of Arachidonic Acid Signalling in NSCLC Tumour Angiogenesis -- 6. Regulation of Adhesion, Migration and Invasion of NSCLC by Arachidonic Acid Pathways -- 7. Modulation of the Immune System in NSCLC by Arachidonic Acid -- 8. Targeting Arachidonic Acid Pathways Using Pharmacological and Natural Agents -- Conclusion -- References -- Index. 
590 |a eBooks on EBSCOhost  |b EBSCO eBook Subscription Academic Collection - Worldwide 
650 0 |a Lungs  |x Cancer. 
650 1 2 |a Lung Neoplasms 
650 6 |a Poumons  |x Cancer. 
650 7 |a HEALTH & FITNESS  |x Diseases  |x Cancer.  |2 bisacsh 
650 7 |a MEDICAL  |x Oncology.  |2 bisacsh 
650 7 |a Lungs  |x Cancer  |2 fast 
700 1 |a Gately, Kathy,  |e editor. 
776 0 8 |i Print version:  |t Lung cancer  |d New York : Nova Science Publishers, [2013]  |z 162618447X (hbk.)  |w (DLC) 2013935077 
830 0 |a Cancer etiology, diagnosis, and treatments. 
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