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Update on polymers for pulmonary drug delivery /

Pulmonary drug delivery has been a rapidly expanding field, moving from the traditional propellant based metered dose inhaler delivery of small asthma drugs, to a broader landscape of new devices and novel drugs for local and systemic delivery. The field has greatly expanded yet the tools for pulmon...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Smyth, Hugh D. C.
Otros Autores: El-Sherbiny, Ibrahim, McConville, Jason Thomas
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Shropshire : Smithers Rapra Technology Ltd., 2013.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • 9781847356550_Front Cover; 9781847356550_Contents; Preface; Contributors ; Chapter 01; 1 Pulmonary Drug Delivery, Concepts and Practice ; 1.1 History and Rationale of Pulmonary Drug Delivery ; 1.2 Diseases and Inhaled Products ; 1.2.1 Asthma ; 1.2.2 Chronic Obstructive Pulmonary Disease ; 1.2.3 Cystic Fibrosis ; 1.3 Rationale for Developing Polymer-based Pulmonary Delivery Systems ; 1.3.1 Drug Protection ; 1.3.2 Drug Release and Targeting ; 1.3.3 Vaccines [41] ; 1.4 Physiological Barriers to Lung Delivery ; 1.4.1 Aerodynamics ; 1.4.2 Mucociliary Clearance ; 1.4.3 Alveolar Macrophages.
  • 1.4.4 Drug Absorption Rates 1.5 Summary ; References ; Chapter 02; 2 Polymers for Pulmonary Drug Delivery based on their Interactions with the Lung: Biodegradation, C; 2.1 Introduction ; 2.1.1 Rationale for the Use of Polymeric Carriers for Pulmonary Drug Delivery ; 2.1.2 Selection Criteria of a Polymeric Carrier for Inhalation Therapy ; 2.1.3 B.