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Fatal flaws : how a misfolded protein baffled scientists and changed the way we look at the brain /
"Discovered and identified as the cause of mad cow disease only three decades ago, the prion is a protein molecule that, when misshapen in the brain, becomes fatal. Novel and controversial, prions have provoked a scientific revolution. They challenge the very foundations of biology: A disease-c...
| Clasificación: | Libro Electrónico |
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| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New Haven :
Yale University Press,
2013.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- The mystery of kuru : a disease like no other
- Barflies and flatworms : how speculation and pure chance advance a new science
- Cannibalism : an answer guaranteed to stir things up
- Igor and Bill : the discoveries that bring kuru to world attention
- The life of a cell : a miraculous, and often precarious, complexity
- The death of a cell : by subterfuge, piracy, or out-and-out assault
- When is a virus not a virus? : when a disease-causing agent reproduces without genes
- Creutzfeldt-Jakob disease : waking up to the potential of a devastating affliction
- Magnificent molecules : the proteins that make life possible
- Protein origami : building the gothic cathedrals of life
- Stanley Prusiner's Heresy : an infectious agent that's a protein and nothing but
- An infectious idea : the campaign for the minds of researchers
- A portrait of the prion : and the experiments that point to their role in the human brain
- Mad cow disease : the uncertain ground where politics and science intersect
- Mad cow in humans : no barrier after all
- The Americas : mad mink, then cows
- Into the wild : deer, elk, moose, and caribou
- Origins : attempting to find where prions come from
- Cats but not dogs : when prions jump the species barrier
- Alzheimer's disease : plaques and tangles but so far no prions
- Parkinson's disease : looking more and more like a prion disease
- Lou Gehrig's disease : the emerging picture of a prion-like process in ALS
- Chronic traumatic encephalopathy : the athletes' plague
- And in the end ...