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Physiological engineering aspects of Penicillium chrysogenum /

The book gives a review of penicillin production by Penicillium chrysogenum, and also deals with a number of general aspects of fungal cultivations, e.g. primary metabolism of filamentous fungi, morphology, monitoring of fungal cultivations, and bioreactor performance (more than 750 references). The...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Nielsen, Jens Høiriis
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Singapore ; River Edge, NJ : World Scientific, ©1997.
Temas:
Acceso en línea:Texto completo

MARC

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100 1 |a Nielsen, Jens Høiriis. 
245 1 0 |a Physiological engineering aspects of Penicillium chrysogenum /  |c J. Nielsen. 
260 |a Singapore ;  |a River Edge, NJ :  |b World Scientific,  |c ©1997. 
300 |a 1 online resource (xvi, 269 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references and index. 
505 0 |a Ch. 1. History and Present Status of Penicillin Production -- Ch. 2. The Microorganism -- Ch. 3. Physiological Engineering -- Ch. 4. Primary Metabolism -- Ch. 5. Penicillin Biosynthesis -- Ch. 6. Morphology in Submerged Cultures -- Ch. 7. Bioreactor Performance -- Ch. 8. Penicillin Production in Fed-batch Cultures. 
588 0 |a Print version record. 
520 |a The book gives a review of penicillin production by Penicillium chrysogenum, and also deals with a number of general aspects of fungal cultivations, e.g. primary metabolism of filamentous fungi, morphology, monitoring of fungal cultivations, and bioreactor performance (more than 750 references). The first two chapters give an introduction to the area of penicillin production; with a review of the history and a survey of the present status of this industrially very important process in the first chapter. In the second chapter is given an introduction to the microorganism, i.e. its nutritional requirements, its taxonomy, and an overview of different strain development programmes. Chapter 3 gives an introduction to the concept of Physiological Engineering. This is followed by a review of various monitoring techniques and different theoretical techniques for analysis of cultivation processes, e.g. mathematic modeling, metabolic flux analysis, and metabolic control analysis. Chapters 4 and 5 give a review of the metabolism, with the primary metabolism being the topic of Chapter 4 and the secondary metabolism, i.e. penicillin biosynthesis, being the topic of Chapter 5. The review of the penicillin biosynthetic pathway is followed by a description of a number of results obtained using metabolic flux and metabolic control analysis. Chapter 6 is devoted to the morphology of the fungus, and it gives a detailed description of the growth mechanisms of filamentous fungi. Chapter 7 deals with the bioreactor performance during fungal cultivations, i.e. medium rheology, gas-liquid mass transfer, and mixing. Finally is the fed-batch process applied for penicillin production described in Chapter 8. It gives an overview of the most important factors influencing penicillin production. 
590 |a eBooks on EBSCOhost  |b EBSCO eBook Subscription Academic Collection - Worldwide 
650 0 |a Penicillium chrysogenum. 
650 0 |a Biotechnology. 
650 0 |a Bioengineering. 
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650 7 |a Biotechnology.  |2 fast  |0 (OCoLC)fst00832729 
650 7 |a Penicillium chrysogenum.  |2 fast  |0 (OCoLC)fst01056905 
650 7 |a Microbiologie industrielle.  |2 ram 
650 7 |a Biotechnologie.  |2 ram 
776 0 8 |i Print version:  |a Nielsen, Jens Høiriis.  |t Physiological engineering aspects of Penicillium chrysogenum.  |d Singapore ; River Edge, NJ : World Scientific, ©1997  |z 9810227655  |w (OCoLC)37548141 
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