Growth hormones : synthesis, regulation & health implications /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Andersdtr, Anne (Editor ), Anderssen, Jon (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : Nova Science Publishers, Inc., Ã2012.
Colección:Endocrinology research and clinical developments.
Metabolic diseases--laboratory and clinical research series.
Temas:
Peptide hormones.
Somatotropin.
Hormones peptidiques.
Somatotrophine.
SCIENCE > Life Sciences > Developmental Biology.
Peptide hormones
Somatotropin
Acceso en línea:Texto completo
Tabla de Contenidos:
  • GROWTH HORMONES: SYNTHESIS, REGULATION AND HEALTH IMPLICATIONS; GROWTH HORMONES: SYNTHESIS, REGULATION AND HEALTH IMPLICATIONS; LIBRARY OF CONGRESS CATALOGING-IN-PUBLICATION DATA; CONTENTS; PREFACE; Chapter 1: BIOTECH PLATFORM FOR DISCOVERY AND ASSESSMENT OF GROWTH HORMONES; 1. MODERN BIOTECHNOLOGY AND THE PRODUCTION OF PROTEIN HORMONES; 2. THE GROWTH HORMONE (GH) FAMILY; 3. GROWTH HORMONES OF ANIMAL ORIGIN; 4. BIOLOGICAL POTENTIAL OF GHS; 5. EXPRESSION SYSTEMS FOR GROWTH HORMONES; 6. TECHNOLOGICAL PLATFORM FOR CLONING GHS; 7. TECHNOLOGICAL PLATFORM FOR PRODUCING RECOMBINANT GHS.
  • 8. CONSTRUCTION OF GHS PRODUCING PICHIA PASTORIS STRAINS9. PRODUCTION AND ANALYSIS OF RECOMBINANT HORMONES IN ERLENMEYER FLASK; 10. PRODUCTION SCALING IN THE BIOREACTOR; 11. SEMIPURIFICATION OF RECOMBINANT HORMONES; 12. TESTING THE BIOLOGICAL ACTIVITY OF RECOMBINANT HORMONES; 13. CONTRIBUTIONS; 14. PERSPECTIVES; ACKNOWLEDGMENTS; REFERENCES; Chapter 2: THEORETICAL APPROACHESTO GROWTH HORMONE SIGNALING; Abstract; 1. Introduction; 2. Mathematical Modeling of Ligand-Receptor Systems; 3. 1:1 Interaction Model; 4. 1:2 Symmetric Interaction Model; 5. 1:2 Symmetric and Sequential Interaction Model.
  • 6. 1:2 Asymmetric and Sequential Interaction Model7. Self-Antagonist Effect; 8. Enhanced Efficiency of GH Ligand Homodimers; 9. Receptor Monomer Versus Receptor Dimer Hypotheses; 10. Conclusion; 11. Acknowledgments; References; Chapter 3: EFFECT OF GROWTH HORMONE ON LIPID METABOLISM
  • BASIC AND CLINICAL ASPECTS; ABSTRACT; ABBREVIATIONS; 1. INTRODUCTION; 2. GROWTH HORMONE: CHEMISTRY, GENE EXPRESSION AND SECRETION CONTROL; 3. GROWTH HORMONE RECEPTOR AND SIGNALING CASCADE; 4. EFFECTS OF GROWTH HORMONE ON LIPID METABOLISM IN THE ADIPOSE TISSUE, LIVER AND SKELETAL MUSCLE.
  • 5. STUDIES OF GROWTH HORMONE SECRETION AND ACTIONS IN HUMANS6. OBESITY, METABOLIC SYNDROME AND GROWTH HORMONE; 7. GROWTH HORMONE DEFICIENCY AND VISCERAL (TRUNCAL) OBESITY; 8. GROWTH HORMONE TREATMENT AND PERSPECTIVES; REFERENCES; Chapter 4: THE HUMAN GROWTH HORMONE: SYNTHESIS, REGULATION AND HEALTH IMPLICATIONS; ABSTRACT; I. INTRODUCTION; II. HGH SYNTHESIS AND REGULATION; III. BIOLOGICAL RELEVANCE AND IMPACT ON HEALTH; CONCLUSION; REFERENCES; Chapter 5: CIRCULATION CONCENTRATION OF ESTRADIOL, GROWTH HORMONE, INSULIN LIKE GROWTH FACTOR AFTER FOLLICLE ASPIRATION IN CATTLE; ABSTRACT.
  • 1. INTRODUCTION2. MATERIALS AND METHODS; 3. RESULT; 4. DISCUSSION; REFERENCES; Chapter 6: STABILITY STUDY OF SOMATROPIN BY CAPILLARY ZONE ELECTROPHORESIS; ABSTRACT; INTRODUCTION; EXPERIMENTAL; RESULTS AND DISCUSSION; CONCLUSION; REFERENCES; Chapter 7: CARDIAC EFFECTS OF GROWTH HORMONE TREATMENT IN PEDIATRIC POPULATIONS; INTRODUCTION; BACKGROUND; GROWTH HORMONE THERAPY IN THE CARDIAC SETTING; ISOLATED GH DEFICIENCY; TURNER SYNDROME; NOONAN SYNDROME; PRADER-WILLI SYNDROME; SMALL FOR GESTATIONAL AGE (SGA); INDUCED GH DEFICIENCY; CONCLUSION; REFERENCES.
  • Chapter 8: RECOMBINANT HUMAN GROWTH HORMONE TREATMENT IN PATIENTS WITH GROWTH DEFICIENCY AND CROHN'S DISEASE
  • NEW PERSPECTIVES.

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