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Tabla de Contenidos:
  • ESTROGENS: BIOCHEMISTRY, THERAPEUTIC USES AND PHYSIOLOGICAL EFFECTS; ESTROGENS: BIOCHEMISTRY, THERAPEUTIC USES AND PHYSIOLOGICAL EFFECTS; Library of Congress Cataloging-in-Publication Data; CONTENTS; PREFACE; Chapter 1: ESTROGENS AS MEDIATORS OF OBESITY-INDUCED INFLAMMATION; ABSTRACT; ABBREVIATIONS; ADIPOSE TISSUE-RELATED INFLAMMATION; ESTROGEN SIGNALING; ESTROGEN TURNOVER IN THE ADIPOSE TISSUE; MODELS OF ESTROGEN INSUFFICIENCY; ESTROGENS AND ADIPOSE TISSUE MASS, DISTRIBUTION AND CELLULARITY; ESTROGENS AND AT INFLAMMATION; XENOESTROGENS AND OBESITY-ASSOCIATED COMPLICATIONS; CONCLUSION.
  • ACKNOWLEDGMENTSREFERENCES; Chapter 2: EFFECTS OF ESTROGEN USE, FOLLICLE-STIMULATING HORMONE AND LUTEINIZING HORMONE ON COGNITIVE TESTS DEMANDING ATTENTION IN POSTMENOPAUSAL WOMEN; INTRODUCTION; METHOD; Sustained Attention; Attention Span; Word Repetition Span; RESULTS; CONCLUSION; AUTHOR CONTRIBUTIONS; ACKNOWLEDGMENTS; REFERENCES; Chapter 3: THE ROLE OF ESTROGENS IN OSTEOARTHRITIS AND INFLAMMATION; ABSTRACT; INTRODUCTION; ESTROGEN RECEPTORS STRUCTURE AND CHARACTERISTICS; ESTROGEN ON INFLAMMATION; ESTROGEN AND AUTOIMMUNE DISEASES: RHEUMATOID ARTHRITIS AND SYSTEMIC LUPUS ERYTHEMATOSUS.
  • ESTROGEN AND OSTEOARTHRITISCONCLUSION; COMPETING INTERESTS; REFERENCES; Chapter 4: ESTROGEN IN REGULATING THE GENDER DISPARITY OF HEPATOCELLULAR CARCINOMA; ABSTRACT; INTRODUCTION; HCC OCCURS PREFERENTIALLY IN MALES, WITH THE SEX DIFFERENCE STARTING FROM CHRONIC HEPATITIS; THE INVOLVEMENT OF ANDROGEN AXIS IN PROMOTING MALE HCC; THE INVOLVEMENT OF ESTROGEN AXIS IN PROTECTING FEMALE HCC: EPIDEMIOLOGICAL EVIDENCE AND ANIMAL STUDIES; WILD TYPE AND VARIANT ESTROGEN RECEPTORSIN NORMAL AND HCC LIVER TISSUES; MOLECULAR MECHANISMS FOR THE PROTECTIVE ROLE OF ESTROGEN AXIS IN FEMALE HCC.
  • THE MECHANISMS OF ESTROGEN AXIS IN PREVENTING HEPATIC FIBROSIS AND STEATOSISTHE REGULATORY MECHANISMS FOR THE DOWN-REGULATION OF ERa IN FEMALE HCC; THE INTERACTION BETWEEN THE HEPATITISVIRUS B AND ESTROGEN PATHWAY; CONCLUSION; ACKNOWLEDGMENTS; REFERENCES; Chapter 5: POST-TRANSCRIPTIONAL EFFECTS OF ESTROGENS ON GENE EXPRESSION: MESSENGER RNA STABILITYAND TRANSLATION REGULATEDBY MICRORNAS AND OTHER FACTORS; ABSTRACT; INTRODUCTION; ESTROGENS STABILIZE AND DESTABILIZESPECIFIC MRNAS; ESTROGENS AFFECT MRNA TRANSLATION; ESTROGEN ACTIONS AND MICRORNAS.
  • MicroRNAs
  • Biogenesis and Regulation of Gene ExpressionEstrogens Regulate Expression of MicroRNA Genes in Responsive Tissues during Normal Physiology and Disease; MicroRNAs Regulate ER Gene Expression and Estrogen Actions; FUTURE THERAPEUTIC APPROACHES TO REGULATINGPOST-TRANSCRIPTIONAL ESTROGEN ACTIONS; CONCLUSION; REFERENCES; INDEX.