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Animal models in cancer research and human disease : applications, outcomes and controversies /
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York :
Nova Biomedical/Nova Science Publishers, Incorporated,
[2013]
|
| Colección: | Microbiology research advances series.
Animal science, issues, and professions series. |
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 049 | |a UAMI | ||
| 245 | 0 | 0 | |a Animal models in cancer research and human disease : |b applications, outcomes and controversies / |c Sean A. Murray, editor. |
| 264 | 1 | |a New York : |b Nova Biomedical/Nova Science Publishers, Incorporated, |c [2013] | |
| 264 | 4 | |c ©2013 | |
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Microbiology research andvances | |
| 490 | 1 | |a Animal science, issues and professions | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 505 | 0 | |a ANIMAL MODELS IN CANCER RESEARCH AND HUMAN DISEASE ; ANIMAL MODELS IN CANCER RESEARCH AND HUMAN DISEASE ; Contents ; Preface ; Murine Models of Sporadic and Inflammation-Related Colon Carcinogenesis with Particular Focus on the AOM/DSS Chemically Induced Colorectal Cancer Model ; Abstract ; Introduction ; A Variety of CRC Models: Benefits and Limits ; Chemically Induced Colon Carcinogenesis in Rodents ; The AOM/DSS Model in the Study of Colorectal Carcinogenesis ; Histogenesis of Colon Cancer in AOM/DSS Model -- from the Emergence of Precancerous Lesions to Late Carcinomas. | |
| 505 | 8 | |a Molecular Events Associated with Colon Carcinogenesis in the AOM/DSS Model and Relevance for Human CRC Wnt/APC/Ý-Catenin Pathway ; K-Ras ; c-Myc ; TGF-Ý ; Cox-2 ; iNOS ; p53 Pathway ; Epigenetic Modifications ; Pathogenesis and Molecular Biology of Colitis-Induced Carcinogenesis in the AOM/DSS Model; Proinflammatory Factors ; Regulatory Factors ; Chemokines ; Toll Like Receptors ; TIR8 ; Heparanase ; Oxidative Stress and DNA Damage; The AOM/DSS Model in Preclinical Studies ; Natural Plant Compounds ; Modulation of Physiological Molecules ; Synthetic Drugs ; Conclusion ; Acknowledgment. | |
| 505 | 8 | |a 3.3. Mechanical Injury Induced Neointimal Hyperplasia 4. Animal Models of Structural Heart Disease ; 4.1. Ischemic Mitral Regurgitation ; Conclusion ; Acknowledgment ; References ; Canine Breast Cancer and Lymphoma as Modelsin Cancer Research ; Abstract ; 1. Introduction ; 1.1. Dogs as Appropriate Animal Models of Human Cancers ; 2. Canine Mammary Tumor Model ; 2.1. Expression Defects of Cell Cycle Regulators in the CMT Model ; Deregulation of p16/INK4A/ARF/INK4B Locus in CMTs ; 2.2. Genome-Wide Comparative Analysis of the Role of Critical Genes Involved in Human and Canine Mammary Tumors. | |
| 505 | 8 | |a 2.3. Expression of miRNAs in Human Breast Cancer and the CMT Model 3. Canine Lymphoma Model ; Conclusion ; References ; Development of Cell Therapeutic Strategies for Alzheimer's Disease Using Animal Models ; Abstract ; Introduction ; Amyloid Cascade Hypothesis ; Transgenic Mice Models of AD ; Therapeutic Strategies Using Transgenic Mice Models of AD ; Microglia in the AD Brain ; Cell Therapeutic Strategies for AD ; Conclusion ; Acknowledgments ; References ; Animal Models for AntineoplasticChemotherapy-Induced Alopecia; Abstract ; Introduction ; The Biology of the Hair Follicles (HFs) | |
| 590 | |a eBooks on EBSCOhost |b EBSCO eBook Subscription Academic Collection - Worldwide | ||
| 650 | 0 | |a Carcinogenesis |x Animal models. | |
| 650 | 0 | |a Diseases |x Animal models. | |
| 650 | 0 | |a Animal models in research |x Moral and ethical aspects. | |
| 650 | 0 | |a Research. | |
| 650 | 0 | |a Carcinogenesis. | |
| 650 | 1 | 2 | |a Disease Models, Animal |
| 650 | 1 | 2 | |a Research |
| 650 | 2 | 2 | |a Ethics |
| 650 | 2 | 2 | |a Carcinogenesis |
| 650 | 6 | |a Cancérogenèse |x Modèles animaux. | |
| 650 | 6 | |a Maladies |x Modèles animaux. | |
| 650 | 6 | |a Modèles animaux dans la recherche |x Aspect moral. | |
| 650 | 6 | |a Recherche. | |
| 650 | 6 | |a Cancérogenèse. | |
| 650 | 7 | |a research (function) |2 aat | |
| 650 | 7 | |a MEDICAL |x Research. |2 bisacsh | |
| 650 | 7 | |a Research |2 fast | |
| 650 | 7 | |a Carcinogenesis |x Animal models |2 fast | |
| 650 | 7 | |a Diseases |x Animal models |2 fast | |
| 700 | 1 | |a Murray, Sean A., |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Animal models in cancer research and human disease. |d New York : Nova Biomedical/Nova Science Publishers, Inc., [2013] |z 1624175872 |w (DLC) 2012954583 |
| 830 | 0 | |a Microbiology research advances series. | |
| 830 | 0 | |a Animal science, issues, and professions series. | |
| 856 | 4 | 0 | |u https://ebsco.uam.elogim.com/login.aspx?direct=true&scope=site&db=nlebk&AN=570679 |z Texto completo |
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| 938 | |a ebrary |b EBRY |n ebr10686658 | ||
| 938 | |a EBSCOhost |b EBSC |n 570679 | ||
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| 994 | |a 92 |b IZTAP | ||