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Alzheimer's disease research compendium /
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York :
Nova Biomedical,
[2013]
|
| Colección: | Neurodegenerative diseases-laboratory and clinical research
Neuoroscience Research Progress |
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 008 | 130405s2013 nyu ob 001 0 eng | ||
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| 020 | |a 1622575113 | ||
| 020 | |z 9781622575107 |q (hardback) | ||
| 020 | |z 1622575105 |q (hardback) | ||
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| 245 | 0 | 0 | |a Alzheimer's disease research compendium / |c Miao-Kun Sun, editor. |
| 264 | 1 | |a New York : |b Nova Biomedical, |c [2013] | |
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 0 | |a Neurodegenerative diseases-laboratory and clinical research | |
| 490 | 0 | |a Neuoroscience Research Progress | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record and CIP data provided by publisher. | |
| 505 | 0 | |a ALZHEIMER'S DISEASE RESEARCH COMPENDIUM; ALZHEIMER'S DISEASE RESEARCH COMPENDIUM; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Chapter 1: SSAO and AÝ in the Vascular Damage of the Temporal Cortex from Alzheimer and Alzheimer with Diabetes Patients; Abstract; Introduction; Experimental Procedures; Human Brain Samples; Immunohistochemistry Technique; Immunopositive Vessels and Neurons Counting; Statistical Analysis; Results; SSAO and AÝ Vessels Immunostaining; SSAO-Positive Vessels and Neuronal Damage; SSAO-Positive Vessels and Glial Activation. | |
| 505 | 8 | |a SSAO-Positive Vessels and Vascular DamageConclusion; Acknowledgments; References; Chapter 2: Amyloid Precursor Protein in Central and Peripheral Cholinergic Synaptopathies; Chapter 2: Amyloid Precursor Protein in Central and Peripheral Cholinergic Synaptopathies; Abstract; Introduction; Functional Role and Metabolism of APP and Derived Fragments; APP Intracellular C-Terminal Domain (AICD); APP Extracellular Domain; Amyloid Peptide; APP and Cholinergic Transmission; APP and Cholinergic Synaptopathies; Conclusion; Acknowledgments; References. | |
| 505 | 8 | |a Chapter 3: In Vivo Analysis Using a Presenilin -1-Specific Inhibitor: Presenilin1-Containing y-Secretase Complexes Mediate the Majority of CNS AB Production in the MouseAbstract; Introduction; Materials and Methods; Synthesis of ZI-10; Cell Free -Secretase Assay; Cell-based Assay for -Secretase Mediated A Production; Animal Handling and Drug Administration; Determination of A 40 Levels in Brain Homogenates and Plasma; Brain and Plasma Drug Exposure Analysis; Brain Slice Uptake Experiment and Sample Preparation; Determination of Fu, plasma by Equilibrium Dialysis Experiment; Results. | |
| 505 | 8 | |a ZI-10 Inhibits A 40 Production in a Cell-free Assay for -Secretase ActivityZI-10 Inhibits A Production in Cultured Cells; ZI-10 Preferentially Inhibits PS1-Mediated A 40 Production; ZI-10 Reduces A 40 Levels in the Mouse Brain but not in the Plasma; Discussion; Acknowledgments; References; Chapter 4: Insight into 'Synaptopathy' in Alzheimer's Disease: From Lifestyle to PS1/N-Cadherin Interaction; Abstract; Introduction; 1) Evidence for 'Synaptopathy' in AD; 2) Implications of Diverse Lifestyles for AD; 3) Molecular Mechanisms of 'Synaptopathy' in AD: Potential Roles of PS1. | |
| 505 | 8 | |a 4) Towards Synapse-targeting Approaches for Prevention and Therapeutics of ADReferences; Chapter 5: Interaction and Stimulation through a Computer: A Program Specially Designed for Mild to Moderate Alzheimer's Patients; Abstract; Introduction; Methodology; Program Concept; 1) Web Conferencing: (Figure 2); 2) Help with Taking Medications; 3) Cognitive Stimulation Program (Figures 3 to 5); Goals; Subjects; Procedure; Outcome Measures; 1) Pre-defined Clinical Questionnaire to Evaluate; 2) Mood; Results; I.1. a) Patients' Social-professional Status and Performance Speed (See Table 1) | |
| 590 | |a eBooks on EBSCOhost |b EBSCO eBook Subscription Academic Collection - Worldwide | ||
| 650 | 0 | |a Alzheimer's disease. | |
| 650 | 2 | |a Alzheimer Disease | |
| 650 | 6 | |a Maladie d'Alzheimer. | |
| 650 | 7 | |a HEALTH & FITNESS |x Diseases |x Alzheimer's & Dementia. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Neurology. |2 bisacsh | |
| 650 | 7 | |a Alzheimer's disease |2 fast | |
| 700 | 1 | |a Sun, Miao-Kun, |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Alzheimer's disease research compendium. |d New York : Nova Biomedical, [2013] |z 9781622575107 |w (DLC) 2012540905 |
| 856 | 4 | 0 | |u https://ebsco.uam.elogim.com/login.aspx?direct=true&scope=site&db=nlebk&AN=548905 |z Texto completo |
| 938 | |a ProQuest Ebook Central |b EBLB |n EBL3020469 | ||
| 938 | |a EBSCOhost |b EBSC |n 548905 | ||
| 994 | |a 92 |b IZTAP | ||